345 related articles for article (PubMed ID: 28570028)
1. Transthyretin stability is critical in assisting beta amyloid clearance- Relevance of transthyretin stabilization in Alzheimer's disease.
Alemi M; Silva SC; Santana I; Cardoso I
CNS Neurosci Ther; 2017 Jul; 23(7):605-619. PubMed ID: 28570028
[TBL] [Abstract][Full Text] [Related]
2. Transthyretin stabilization by iododiflunisal promotes amyloid-β peptide clearance, decreases its deposition, and ameliorates cognitive deficits in an Alzheimer's disease mouse model.
Ribeiro CA; Oliveira SM; Guido LF; Magalhães A; Valencia G; Arsequell G; Saraiva MJ; Cardoso I
J Alzheimers Dis; 2014; 39(2):357-70. PubMed ID: 24169237
[TBL] [Abstract][Full Text] [Related]
3. Transthyretin participates in beta-amyloid transport from the brain to the liver--involvement of the low-density lipoprotein receptor-related protein 1?
Alemi M; Gaiteiro C; Ribeiro CA; Santos LM; Gomes JR; Oliveira SM; Couraud PO; Weksler B; Romero I; Saraiva MJ; Cardoso I
Sci Rep; 2016 Feb; 6():20164. PubMed ID: 26837706
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.
Shackleton B; Crawford F; Bachmeier C
Fluids Barriers CNS; 2016 Aug; 13(1):14. PubMed ID: 27503326
[TBL] [Abstract][Full Text] [Related]
5. Insights on the Interaction between Transthyretin and Aβ in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal.
Gimeno A; Santos LM; Alemi M; Rivas J; Blasi D; Cotrina EY; Llop J; Valencia G; Cardoso I; Quintana J; Arsequell G; Jiménez-Barbero J
J Med Chem; 2017 Jul; 60(13):5749-5758. PubMed ID: 28587455
[TBL] [Abstract][Full Text] [Related]
6. Stability of the transthyretin molecule as a key factor in the interaction with a-beta peptide--relevance in Alzheimer's disease.
Ribeiro CA; Saraiva MJ; Cardoso I
PLoS One; 2012; 7(9):e45368. PubMed ID: 23028965
[TBL] [Abstract][Full Text] [Related]
7. LRP1 in brain vascular smooth muscle cells mediates local clearance of Alzheimer's amyloid-β.
Kanekiyo T; Liu CC; Shinohara M; Li J; Bu G
J Neurosci; 2012 Nov; 32(46):16458-65. PubMed ID: 23152628
[TBL] [Abstract][Full Text] [Related]
8. 1,25-Dihydroxyvitamin D3 regulates expression of LRP1 and RAGE in vitro and in vivo, enhancing Aβ1-40 brain-to-blood efflux and peripheral uptake transport.
Guo YX; He LY; Zhang M; Wang F; Liu F; Peng WX
Neuroscience; 2016 May; 322():28-38. PubMed ID: 26820600
[TBL] [Abstract][Full Text] [Related]
9. Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in vivo Molecular Imaging Study1.
Rejc L; Gómez-Vallejo V; Rios X; Cossío U; Baz Z; Mujica E; Gião T; Cotrina EY; Jiménez-Barbero J; Quintana J; Arsequell G; Cardoso I; Llop J
J Alzheimers Dis; 2020; 77(1):99-112. PubMed ID: 32804152
[TBL] [Abstract][Full Text] [Related]
10. Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD.
Rios X; Gómez-Vallejo V; Martín A; Cossío U; Morcillo MÁ; Alemi M; Cardoso I; Quintana J; Jiménez-Barbero J; Cotrina EY; Valencia G; Arsequell G; Llop J
Sci Rep; 2019 Sep; 9(1):13672. PubMed ID: 31541162
[TBL] [Abstract][Full Text] [Related]
11. Neuronal production of transthyretin in human and murine Alzheimer's disease: is it protective?
Li X; Masliah E; Reixach N; Buxbaum JN
J Neurosci; 2011 Aug; 31(35):12483-90. PubMed ID: 21880910
[TBL] [Abstract][Full Text] [Related]
12. Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism.
Ma Q; Zhao Z; Sagare AP; Wu Y; Wang M; Owens NC; Verghese PB; Herz J; Holtzman DM; Zlokovic BV
Mol Neurodegener; 2018 Oct; 13(1):57. PubMed ID: 30340601
[TBL] [Abstract][Full Text] [Related]
13. Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, Aβ Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer's Disease Drug Discovery.
Cotrina EY; Gimeno A; Llop J; Jiménez-Barbero J; Quintana J; Valencia G; Cardoso I; Prohens R; Arsequell G
J Med Chem; 2020 Mar; 63(6):3205-3214. PubMed ID: 32124607
[TBL] [Abstract][Full Text] [Related]
14. Mechanisms of transthyretin inhibition of β-amyloid aggregation in vitro.
Li X; Zhang X; Ladiwala AR; Du D; Yadav JK; Tessier PM; Wright PE; Kelly JW; Buxbaum JN
J Neurosci; 2013 Dec; 33(50):19423-33. PubMed ID: 24336709
[TBL] [Abstract][Full Text] [Related]
15. Accelerated Abeta deposition in APPswe/PS1deltaE9 mice with hemizygous deletions of TTR (transthyretin).
Choi SH; Leight SN; Lee VM; Li T; Wong PC; Johnson JA; Saraiva MJ; Sisodia SS
J Neurosci; 2007 Jun; 27(26):7006-10. PubMed ID: 17596449
[TBL] [Abstract][Full Text] [Related]
16. Differences in amyloid-β clearance across mouse and human blood-brain barrier models: kinetic analysis and mechanistic modeling.
Qosa H; Abuasal BS; Romero IA; Weksler B; Couraud PO; Keller JN; Kaddoumi A
Neuropharmacology; 2014 Apr; 79():668-78. PubMed ID: 24467845
[TBL] [Abstract][Full Text] [Related]
17. Transthyretin neuroprotection in Alzheimer's disease is dependent on proteolysis.
Silva CS; Eira J; Ribeiro CA; Oliveira Â; Sousa MM; Cardoso I; Liz MA
Neurobiol Aging; 2017 Nov; 59():10-14. PubMed ID: 28780366
[TBL] [Abstract][Full Text] [Related]
18. The concerted amyloid-beta clearance of LRP1 and ABCB1/P-gp across the blood-brain barrier is linked by PICALM.
Storck SE; Hartz AMS; Bernard J; Wolf A; Kachlmeier A; Mahringer A; Weggen S; Pahnke J; Pietrzik CU
Brain Behav Immun; 2018 Oct; 73():21-33. PubMed ID: 30041013
[TBL] [Abstract][Full Text] [Related]
19. Chronic cerebral hypoperfusion alters amyloid-β transport related proteins in the cortical blood vessels of Alzheimer's disease model mouse.
Shang J; Yamashita T; Tian F; Li X; Liu X; Shi X; Nakano Y; Tsunoda K; Nomura E; Sasaki R; Tadokoro K; Sato K; Takemoto M; Hishikawa N; Ohta Y; Abe K
Brain Res; 2019 Nov; 1723():146379. PubMed ID: 31415766
[TBL] [Abstract][Full Text] [Related]
20. Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer.
Cotrina EY; Oliveira Â; Leite JP; Llop J; Gales L; Quintana J; Cardoso I; Arsequell G
Int J Mol Sci; 2020 Sep; 21(19):. PubMed ID: 32998442
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
