223 related articles for article (PubMed ID: 28571538)
1. High Throughput Screening Assay to Identify Modulators of IL-17 Expression.
Boudjelal M; Ruiz-Avendano AM; Colmenarejo G; Senar-Sancho SA; Barnes A; Harrison SA
Comb Chem High Throughput Screen; 2017; 20(9):804-819. PubMed ID: 28571538
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of RORγt activity and Th17 differentiation by a set of novel compounds.
Ding Q; Zhao M; Bai C; Yu B; Huang Z
BMC Immunol; 2015 May; 16():32. PubMed ID: 26021566
[TBL] [Abstract][Full Text] [Related]
3. Identification of Tetraazacyclic Compounds as Novel Potent Inhibitors Antagonizing RORγt Activity and Suppressing Th17 Cell Differentiation.
Ding Q; Zhao M; Yu B; Bai C; Huang Z
PLoS One; 2015; 10(9):e0137711. PubMed ID: 26368822
[TBL] [Abstract][Full Text] [Related]
4. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo.
Skepner J; Ramesh R; Trocha M; Schmidt D; Baloglu E; Lobera M; Carlson T; Hill J; Orband-Miller LA; Barnes A; Boudjelal M; Sundrud M; Ghosh S; Yang J
J Immunol; 2014 Mar; 192(6):2564-75. PubMed ID: 24516202
[TBL] [Abstract][Full Text] [Related]
5. Development of a Topical Treatment for Psoriasis Targeting RORγ: From Bench to Skin.
Smith SH; Peredo CE; Takeda Y; Bui T; Neil J; Rickard D; Millerman E; Therrien JP; Nicodeme E; Brusq JM; Birault V; Viviani F; Hofland H; Jetten AM; Cote-Sierra J
PLoS One; 2016; 11(2):e0147979. PubMed ID: 26870941
[TBL] [Abstract][Full Text] [Related]
6. The evolution paths of some reprehensive scaffolds of RORγt modulators, a perspective from medicinal chemistry.
Li Z; Liu T; He X; Bai C
Eur J Med Chem; 2022 Jan; 228():113962. PubMed ID: 34776280
[TBL] [Abstract][Full Text] [Related]
7. Oral administration of a novel RORγt antagonist attenuates psoriasis-like skin lesion of two independent mouse models through neutralization of IL-17.
Takaishi M; Ishizaki M; Suzuki K; Isobe T; Shimozato T; Sano S
J Dermatol Sci; 2017 Jan; 85(1):12-19. PubMed ID: 27726924
[TBL] [Abstract][Full Text] [Related]
8. Inhibiting RORγt/Th17 axis for autoimmune disorders.
Isono F; Fujita-Sato S; Ito S
Drug Discov Today; 2014 Aug; 19(8):1205-11. PubMed ID: 24792721
[TBL] [Abstract][Full Text] [Related]
9. Pharmacological inhibition of RORγt suppresses the Th17 pathway and alleviates arthritis in vivo.
Guendisch U; Weiss J; Ecoeur F; Riker JC; Kaupmann K; Kallen J; Hintermann S; Orain D; Dawson J; Billich A; Guntermann C
PLoS One; 2017; 12(11):e0188391. PubMed ID: 29155882
[TBL] [Abstract][Full Text] [Related]
10. Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt.
Gege C; Albers M; Kinzel O; Kleymann G; Schlüter T; Steeneck C; Hoffmann T; Xue X; Cummings MD; Spurlino J; Milligan C; Fourie AM; Edwards JP; Leonard K; Coe K; Scott B; Pippel D; Goldberg SD
Bioorg Med Chem Lett; 2020 Jun; 30(12):127205. PubMed ID: 32336498
[TBL] [Abstract][Full Text] [Related]
11. 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives as inhibitors of full-length RORγt.
Lao C; Zhou X; Chen H; Wei F; Huang Z; Bai C
Bioorg Chem; 2019 Sep; 90():103077. PubMed ID: 31323598
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of Interleukin-23-Mediated Inflammation with a Novel Small Molecule Inverse Agonist of ROR
Gauld SB; Jacquet S; Gauvin D; Wallace C; Wang Y; McCarthy R; Goess C; Leys L; Huang S; Su Z; Edelmayer R; Wetter J; Salte K; McGaraughty SP; Argiriadi MA; Honore P; Luccarini JM; Bressac D; Desino K; Breinlinger E; Cusack K; Potin D; Kort ME; Masson PJ
J Pharmacol Exp Ther; 2019 Oct; 371(1):208-218. PubMed ID: 31375639
[TBL] [Abstract][Full Text] [Related]
13. High-Throughput Screening Using a Whole-Cell Virus Replication Reporter Gene Assay to Identify Inhibitory Compounds against Rift Valley Fever Virus Infection.
Islam MK; Baudin M; Eriksson J; Öberg C; Habjan M; Weber F; Överby AK; Ahlm C; Evander M
J Biomol Screen; 2016 Apr; 21(4):354-62. PubMed ID: 26762502
[TBL] [Abstract][Full Text] [Related]
14. Identification and structure activity relationships of quinoline tertiary alcohol modulators of RORγt.
Kummer DA; Cummings MD; Abad M; Barbay J; Castro G; Wolin R; Kreutter KD; Maharoof U; Milligan C; Nishimura R; Pierce J; Schalk-Hihi C; Spurlino J; Urbanski M; Venkatesan H; Wang A; Woods C; Xue X; Edwards JP; Fourie AM; Leonard K
Bioorg Med Chem Lett; 2017 May; 27(9):2047-2057. PubMed ID: 28318945
[TBL] [Abstract][Full Text] [Related]
15. Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Agonists as Potential Small Molecule Therapeutics for Cancer Immunotherapy.
Qiu R; Wang Y
J Med Chem; 2018 Jul; 61(14):5794-5804. PubMed ID: 29412659
[TBL] [Abstract][Full Text] [Related]
16. The expression change of RORγt, BATF, and IL-17 in Chinese vitiligo patients with 308 nanometers excimer laser treatment.
Wang LM; Zhang B; Li JJ; Zhou YC; Wang DX
Dermatol Ther; 2018 May; 31(3):e12598. PubMed ID: 29642271
[TBL] [Abstract][Full Text] [Related]
17. [Generation of engineering Th17 cells and its function evaluation].
Zhang HX; Chen C; Zeng LY; Zhang Y; Xu KL
Zhonghua Xue Ye Xue Za Zhi; 2011 Dec; 32(12):825-9. PubMed ID: 22339955
[TBL] [Abstract][Full Text] [Related]
18. Identification of novel quinazolinedione derivatives as RORγt inverse agonist.
Fukase Y; Sato A; Tomata Y; Ochida A; Kono M; Yonemori K; Koga K; Okui T; Yamasaki M; Fujitani Y; Nakagawa H; Koyama R; Nakayama M; Skene R; Sang BC; Hoffman I; Shirai J; Yamamoto S
Bioorg Med Chem; 2018 Feb; 26(3):721-736. PubMed ID: 29342416
[TBL] [Abstract][Full Text] [Related]
19. Expression of human gene coding RORγT receptor depends on the Sp2 transcription factor.
Ratajewski M; Walczak-Drzewiecka A; Gorzkiewicz M; Sałkowska A; Dastych J
J Leukoc Biol; 2016 Nov; 100(5):1213-1223. PubMed ID: 27256574
[TBL] [Abstract][Full Text] [Related]
20. Targeting Th17 Cells with Small Molecules and Small Interference RNA.
Lin H; Song P; Zhao Y; Xue LJ; Liu Y; Chu CQ
Mediators Inflamm; 2015; 2015():290657. PubMed ID: 26792955
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]