BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

96 related articles for article (PubMed ID: 28574711)

  • 1. General Procedures for the Lithiation/Trapping of N-Boc Piperazines.
    Firth JD; O'Brien P; Ferris L
    J Org Chem; 2017 Jul; 82(13):7023-7031. PubMed ID: 28574711
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of Enantiopure Piperazines via Asymmetric Lithiation-Trapping of N-Boc Piperazines: Unexpected Role of the Electrophile and Distal N-Substituent.
    Firth JD; O'Brien P; Ferris L
    J Am Chem Soc; 2016 Jan; 138(2):651-9. PubMed ID: 26683825
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An experimental and in situ IR spectroscopic study of the lithiation-substitution of N-Boc-2-phenylpyrrolidine and -piperidine: controlling the formation of quaternary stereocenters.
    Sheikh NS; Leonori D; Barker G; Firth JD; Campos KR; Meijer AJ; O'Brien P; Coldham I
    J Am Chem Soc; 2012 Mar; 134(11):5300-8. PubMed ID: 22339321
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Diamine-free lithiation-trapping of N-Boc heterocycles using s-BuLi in THF.
    Barker G; O'Brien P; Campos KR
    Org Lett; 2010 Sep; 12(18):4176-9. PubMed ID: 20718476
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Asymmetric lithiation trapping of N-Boc heterocycles at temperatures above -78 °C.
    Gelardi G; Barker G; O'Brien P; Blakemore DC
    Org Lett; 2013 Nov; 15(21):5424-7. PubMed ID: 24180685
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enantioselective, palladium-catalyzed α-arylation of N-Boc pyrrolidine: in situ react IR spectroscopic monitoring, scope, and synthetic applications.
    Barker G; McGrath JL; Klapars A; Stead D; Zhou G; Campos KR; O'Brien P
    J Org Chem; 2011 Aug; 76(15):5936-53. PubMed ID: 21714542
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of 1-substituted tetrahydroisoquinolines by lithiation and electrophilic quenching guided by in situ IR and NMR spectroscopy and application to the synthesis of salsolidine, carnegine and laudanosine.
    Li X; Leonori D; Sheikh NS; Coldham I
    Chemistry; 2013 Jun; 19(24):7724-30. PubMed ID: 23677770
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of substituted tetrahydroisoquinolines by lithiation then electrophilic quench.
    Talk RA; Duperray A; Li X; Coldham I
    Org Biomol Chem; 2016 Jun; 14(21):4908-17. PubMed ID: 27169500
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and kinetic resolution of substituted tetrahydroquinolines by lithiation then electrophilic quench.
    Carter N; Li X; Reavey L; Meijer AJHM; Coldham I
    Chem Sci; 2018 Feb; 9(5):1352-1357. PubMed ID: 29675183
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reactivity series for s-BuLi/diamine-mediated lithiation of N-Boc pyrrolidine: applications in catalysis and lithiation of N-Boc piperidine.
    McGrath MJ; Bilke JL; O'Brien P
    Chem Commun (Camb); 2006 Jun; (24):2607-9. PubMed ID: 16779493
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preparation and Regioselective Magnesiation or Lithiation of Bis(trimethylsilyl)methyl-Substituted Heteroaryls for the Generation of Highly Functionalized Heterocycles.
    Klatt T; Werner V; Maximova MG; Didier D; Apeloig Y; Knochel P
    Chemistry; 2015 May; 21(21):7830-4. PubMed ID: 25864885
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enantioselective α-Arylation of O-Carbamates via Sparteine-Mediated Lithiation and Negishi Cross-Coupling.
    Royal T; Baumgartner Y; Baudoin O
    Org Lett; 2017 Jan; 19(1):166-169. PubMed ID: 27995794
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Preparation of 1-Substituted Tetrahydro-β-carbolines by Lithiation-Substitution.
    Cochrane EJ; Hassall LA; Coldham I
    J Org Chem; 2015 Jun; 80(11):5964-9. PubMed ID: 25974712
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ligand-controlled α- and β-arylation of acyclic N-Boc amines.
    Millet A; Dailler D; Larini P; Baudoin O
    Angew Chem Int Ed Engl; 2014 Mar; 53(10):2678-82. PubMed ID: 24504659
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Asymmetric lithiation-substitution sequences of substituted allylamines.
    Kim DD; Lee SJ; Beak P
    J Org Chem; 2005 Jul; 70(14):5376-86. PubMed ID: 15989316
    [TBL] [Abstract][Full Text] [Related]  

  • 16. α-Functionalisation of Cyclic Sulfides Enabled by Lithiation Trapping.
    Seling N; Atobe M; Kasten K; Firth JD; Karadakov PB; Goldberg FW; O'Brien P
    Angew Chem Int Ed Engl; 2024 Jan; 63(2):e202314423. PubMed ID: 37984884
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Regiodivergent enantioselective C-H functionalization of Boc-1,3-oxazinanes and application to the synthesis of β
    Lin W; Zhang KF; Baudoin O
    Nat Catal; 2019 Oct; 2(10):882-888. PubMed ID: 31620675
    [TBL] [Abstract][Full Text] [Related]  

  • 18. On the synthesis of α-amino sulfoxides.
    Rayner PJ; Gelardi G; O'Brien P; Horan RA; Blakemore DC
    Org Biomol Chem; 2014 Jun; 12(21):3499-512. PubMed ID: 24759885
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stereocontrolled lithiation/trapping of chiral 2-alkylideneaziridines: investigation into the role of the aziridine nitrogen stereodynamics.
    Mansueto R; Degennaro L; Brière JF; Griffin K; Shipman M; Florio S; Luisi R
    Org Biomol Chem; 2014 Nov; 12(42):8505-11. PubMed ID: 25232795
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis of 1,1-disubstituted tetrahydroisoquinolines by lithiation and substitution, with in situ IR spectroscopy and configurational stability studies.
    Li X; Coldham I
    J Am Chem Soc; 2014 Apr; 136(15):5551-4. PubMed ID: 24707968
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.