BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

355 related articles for article (PubMed ID: 28575672)

  • 1. A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability.
    Tan SLW; Chadha S; Liu Y; Gabasova E; Perera D; Ahmed K; Constantinou S; Renaudin X; Lee M; Aebersold R; Venkitaraman AR
    Cell; 2017 Jun; 169(6):1105-1118.e15. PubMed ID: 28575672
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
    Kim TM; Son MY; Dodds S; Hu L; Hasty P
    Mutat Res; 2014; 766-767():66-72. PubMed ID: 25847274
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Smarcal1-Mediated Fork Reversal Triggers Mre11-Dependent Degradation of Nascent DNA in the Absence of Brca2 and Stable Rad51 Nucleofilaments.
    Kolinjivadi AM; Sannino V; De Antoni A; Zadorozhny K; Kilkenny M; Técher H; Baldi G; Shen R; Ciccia A; Pellegrini L; Krejci L; Costanzo V
    Mol Cell; 2017 Sep; 67(5):867-881.e7. PubMed ID: 28757209
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deletion of BRCA2 exon 27 causes defects in response to both stalled and collapsed replication forks.
    Kim TM; Son MY; Dodds S; Hu L; Hasty P
    Mutat Res; 2014; 766-767():66-72. PubMed ID: 25773776
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.
    Schlacher K; Christ N; Siaud N; Egashira A; Wu H; Jasin M
    Cell; 2011 May; 145(4):529-42. PubMed ID: 21565612
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers.
    Taglialatela A; Alvarez S; Leuzzi G; Sannino V; Ranjha L; Huang JW; Madubata C; Anand R; Levy B; Rabadan R; Cejka P; Costanzo V; Ciccia A
    Mol Cell; 2017 Oct; 68(2):414-430.e8. PubMed ID: 29053959
    [TBL] [Abstract][Full Text] [Related]  

  • 7. BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2.
    Bhatia V; Barroso SI; García-Rubio ML; Tumini E; Herrera-Moyano E; Aguilera A
    Nature; 2014 Jul; 511(7509):362-5. PubMed ID: 24896180
    [TBL] [Abstract][Full Text] [Related]  

  • 8. E3 ligase RFWD3 is a novel modulator of stalled fork stability in BRCA2-deficient cells.
    Duan H; Mansour S; Reed R; Gillis MK; Parent B; Liu B; Sztupinszki Z; Birkbak N; Szallasi Z; Elia AEH; Garber JE; Pathania S
    J Cell Biol; 2020 Jun; 219(6):. PubMed ID: 32391871
    [TBL] [Abstract][Full Text] [Related]  

  • 9. WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells.
    Datta A; Biswas K; Sommers JA; Thompson H; Awate S; Nicolae CM; Thakar T; Moldovan GL; Shoemaker RH; Sharan SK; Brosh RM
    Nat Commun; 2021 Nov; 12(1):6561. PubMed ID: 34772932
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Replication fork reversal triggers fork degradation in BRCA2-defective cells.
    Mijic S; Zellweger R; Chappidi N; Berti M; Jacobs K; Mutreja K; Ursich S; Ray Chaudhuri A; Nussenzweig A; Janscak P; Lopes M
    Nat Commun; 2017 Oct; 8(1):859. PubMed ID: 29038466
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Brca2, Rad51 and Mre11: performing balancing acts on replication forks.
    Costanzo V
    DNA Repair (Amst); 2011 Oct; 10(10):1060-5. PubMed ID: 21900052
    [TBL] [Abstract][Full Text] [Related]  

  • 12. BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.
    Kang Z; Fu P; Alcivar AL; Fu H; Redon C; Foo TK; Zuo Y; Ye C; Baxley R; Madireddy A; Buisson R; Bielinsky AK; Zou L; Shen Z; Aladjem MI; Xia B
    Nat Commun; 2021 Oct; 12(1):5966. PubMed ID: 34645815
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Heterozygous mutations in PALB2 cause DNA replication and damage response defects.
    Nikkilä J; Parplys AC; Pylkäs K; Bose M; Huo Y; Borgmann K; Rapakko K; Nieminen P; Xia B; Pospiech H; Winqvist R
    Nat Commun; 2013; 4():2578. PubMed ID: 24153426
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The BRCA2 and CDKN1A-interacting protein (BCCIP) stabilizes stalled replication forks and prevents degradation of nascent DNA.
    Singh B; Roy Chowdhury S; Mansuri MS; Pillai SJ; Mehrotra S
    FEBS Lett; 2022 Aug; 596(16):2041-2055. PubMed ID: 35592921
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aneuploidy and a deregulated DNA damage response suggest haploinsufficiency in breast tissues of
    Karaayvaz-Yildirim M; Silberman RE; Langenbucher A; Saladi SV; Ross KN; Zarcaro E; Desmond A; Yildirim M; Vivekanandan V; Ravichandran H; Mylavagnanam R; Specht MC; Ramaswamy S; Lawrence M; Amon A; Ellisen LW
    Sci Adv; 2020 Jan; 6(5):eaay2611. PubMed ID: 32064343
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.
    Tacconi EM; Lai X; Folio C; Porru M; Zonderland G; Badie S; Michl J; Sechi I; Rogier M; Matía García V; Batra AS; Rueda OM; Bouwman P; Jonkers J; Ryan A; Reina-San-Martin B; Hui J; Tang N; Bruna A; Biroccio A; Tarsounas M
    EMBO Mol Med; 2017 Oct; 9(10):1398-1414. PubMed ID: 28729482
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Abro1 maintains genome stability and limits replication stress by protecting replication fork stability.
    Xu S; Wu X; Wu L; Castillo A; Liu J; Atkinson E; Paul A; Su D; Schlacher K; Komatsu Y; You MJ; Wang B
    Genes Dev; 2017 Jul; 31(14):1469-1482. PubMed ID: 28860160
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MRE11 and EXO1 nucleases degrade reversed forks and elicit MUS81-dependent fork rescue in BRCA2-deficient cells.
    Lemaçon D; Jackson J; Quinet A; Brickner JR; Li S; Yazinski S; You Z; Ira G; Zou L; Mosammaparast N; Vindigni A
    Nat Commun; 2017 Oct; 8(1):860. PubMed ID: 29038425
    [TBL] [Abstract][Full Text] [Related]  

  • 19. BRCA2 deficiency reveals that oxidative stress impairs RNaseH1 function to cripple mitochondrial DNA maintenance.
    Renaudin X; Lee M; Shehata M; Surmann EM; Venkitaraman AR
    Cell Rep; 2021 Aug; 36(5):109478. PubMed ID: 34348152
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Perturbing cohesin dynamics drives MRE11 nuclease-dependent replication fork slowing.
    Carvajal-Maldonado D; Byrum AK; Jackson J; Wessel S; Lemaçon D; Guitton-Sert L; Quinet A; Tirman S; Graziano S; Masson JY; Cortez D; Gonzalo S; Mosammaparast N; Vindigni A
    Nucleic Acids Res; 2019 Feb; 47(3):1294-1310. PubMed ID: 29917110
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.