These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

205 related articles for article (PubMed ID: 28576766)

  • 1. Comparative Evaluation of Plasma Bile Acids, Dehydroepiandrosterone Sulfate, Hexadecanedioate, and Tetradecanedioate with Coproporphyrins I and III as Markers of OATP Inhibition in Healthy Subjects.
    Shen H; Chen W; Drexler DM; Mandlekar S; Holenarsipur VK; Shields EE; Langish R; Sidik K; Gan J; Humphreys WG; Marathe P; Lai Y
    Drug Metab Dispos; 2017 Aug; 45(8):908-919. PubMed ID: 28576766
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Coproporphyrins in Plasma and Urine Can Be Appropriate Clinical Biomarkers to Recapitulate Drug-Drug Interactions Mediated by Organic Anion Transporting Polypeptide Inhibition.
    Lai Y; Mandlekar S; Shen H; Holenarsipur VK; Langish R; Rajanna P; Murugesan S; Gaud N; Selvam S; Date O; Cheng Y; Shipkova P; Dai J; Humphreys WG; Marathe P
    J Pharmacol Exp Ther; 2016 Sep; 358(3):397-404. PubMed ID: 27317801
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comprehensive Evaluation of the Utility of 20 Endogenous Molecules as Biomarkers of OATP1B Inhibition Compared with Rosuvastatin and Coproporphyrin I.
    Barnett S; Ogungbenro K; Ménochet K; Shen H; Humphreys WG; Galetin A
    J Pharmacol Exp Ther; 2019 Jan; 368(1):125-135. PubMed ID: 30314992
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Coproporphyrins I and III as Functional Markers of OATP1B Activity: In Vitro and In Vivo Evaluation in Preclinical Species.
    Shen H; Dai J; Liu T; Cheng Y; Chen W; Freeden C; Zhang Y; Humphreys WG; Marathe P; Lai Y
    J Pharmacol Exp Ther; 2016 May; 357(2):382-93. PubMed ID: 26907622
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug-Drug Interaction and Associated Biomarker Levels in Healthy Volunteers.
    Yee SW; Giacomini MM; Shen H; Humphreys WG; Horng H; Brian W; Lai Y; Kroetz DL; Giacomini KM
    Clin Transl Sci; 2019 Jul; 12(4):388-399. PubMed ID: 30982223
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dehydroepiandrosterone sulfate, a useful endogenous probe for evaluation of drug-drug interaction on hepatic organic anion transporting polypeptide (OATP) in cynomolgus monkeys.
    Watanabe M; Watanabe T; Yabuki M; Tamai I
    Drug Metab Pharmacokinet; 2015 Apr; 30(2):198-204. PubMed ID: 25989893
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Detection of Weak Organic Anion-Transporting Polypeptide 1B Inhibition by Probenecid with Plasma-Based Coproporphyrin in Humans.
    Zhang Y; Holenarsipur VK; Kandoussi H; Zeng J; Mariappan TT; Sinz M; Shen H
    Drug Metab Dispos; 2020 Oct; 48(10):841-848. PubMed ID: 32723847
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Further Studies to Support the Use of Coproporphyrin I and III as Novel Clinical Biomarkers for Evaluating the Potential for Organic Anion Transporting Polypeptide 1B1 and OATP1B3 Inhibition.
    Shen H; Christopher L; Lai Y; Gong J; Kandoussi H; Garonzik S; Perera V; Garimella T; Humphreys WG
    Drug Metab Dispos; 2018 Aug; 46(8):1075-1082. PubMed ID: 29777022
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparative Evaluation of Dehydroepiandrosterone Sulfate Potential to Predict Hepatic Organic Anion Transporting Polypeptide Transporter-Based Drug-Drug Interactions.
    Nishizawa K; Nakanishi T; Tamai I
    Drug Metab Dispos; 2017 Feb; 45(2):224-227. PubMed ID: 27934638
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Role of Coproporphyrins As Endogenous Biomarkers for Organic Anion Transporting Polypeptide 1B Inhibition-Progress from 2016 to 2023.
    Lai Y
    Drug Metab Dispos; 2023 Aug; 51(8):950-961. PubMed ID: 37407093
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In Vivo.
    Niu C; Wang Y; Zhao X; Tep S; Murakami E; Subramanian R; Smith B; Lai Y
    Drug Metab Dispos; 2019 Dec; 47(12):1433-1442. PubMed ID: 31582395
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A fully automated and validated human plasma LC-MS/MS assay for endogenous OATP biomarkers coproporphyrin-I and coproporphyrin-III.
    King-Ahmad A; Clemens S; Ramanathan R; Zhang Y; Raha N; Zhang Y; Holliman C; Rodrigues AD; Li F
    Bioanalysis; 2018 May; 10(9):691-701. PubMed ID: 29747517
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluation of cynomolgus monkeys for the identification of endogenous biomarkers for hepatic transporter inhibition and as a translatable model to predict pharmacokinetic interactions with statins in humans.
    Chu X; Shih SJ; Shaw R; Hentze H; Chan GH; Owens K; Wang S; Cai X; Newton D; Castro-Perez J; Salituro G; Palamanda J; Fernandis A; Ng CK; Liaw A; Savage MJ; Evers R
    Drug Metab Dispos; 2015 Jun; 43(6):851-63. PubMed ID: 25813937
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Absence of OATP1B (Organic Anion-Transporting Polypeptide) Induction by Rifampin in Cynomolgus Monkeys: Determination Using the Endogenous OATP1B Marker Coproporphyrin and Tissue Gene Expression.
    Zhang Y; Chen C; Chen SJ; Chen XQ; Shuster DJ; Puszczalo PD; Fancher RM; Yang Z; Sinz M; Shen H
    J Pharmacol Exp Ther; 2020 Oct; 375(1):139-151. PubMed ID: 32719071
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Organic anion transporting polypeptide (OATP)-mediated transport of coproporphyrins I and III.
    Bednarczyk D; Boiselle C
    Xenobiotica; 2016; 46(5):457-66. PubMed ID: 26383540
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Coproporphyrin-I as a Selective OATP1B Biomarker Can Be Used to Delineate the Mechanisms of Complex Drug-Drug Interactions: Cedirogant Case Study.
    Kikuchi R; Qian Y; Badawi M; Savaryn JP; Gannu S; Eldred A; Hao S; Salem AH; Liu W; Klein CE; Mohamed MF
    Clin Pharmacol Ther; 2024 Nov; 116(5):1334-1342. PubMed ID: 39102854
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Repression of Organic Anion Transporting Polypeptide (OATP) 1B Expression and Increase of Plasma Coproporphyrin Level as Evidence for OATP1B Downregulation in Cynomolgus Monkeys Treated with Chenodeoxycholic Acid.
    Zhang Y; Chen SJ; Chen C; Chen XQ; Chatterjee S; Shuster DJ; Dexter H; Armstrong L; Joshi EM; Yang Z; Shen H
    Drug Metab Dispos; 2022 Aug; 50(8):1077-1086. PubMed ID: 35636769
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Leveraging of Rifampicin-Dosed Cynomolgus Monkeys to Identify Bile Acid 3-O-Sulfate Conjugates as Potential Novel Biomarkers for Organic Anion-Transporting Polypeptides.
    Thakare R; Gao H; Kosa RE; Bi YA; Varma MVS; Cerny MA; Sharma R; Kuhn M; Huang B; Liu Y; Yu A; Walker GS; Niosi M; Tremaine L; Alnouti Y; Rodrigues AD
    Drug Metab Dispos; 2017 Jul; 45(7):721-733. PubMed ID: 28396527
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biomarker-Informed Model-Based Risk Assessment of Organic Anion Transporting Polypeptide 1B Mediated Drug-Drug Interactions.
    Kimoto E; Costales C; West MA; Bi YA; Vourvahis M; David Rodrigues A; Varma MVS
    Clin Pharmacol Ther; 2022 Feb; 111(2):404-415. PubMed ID: 34605015
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Further Evaluation of Coproporphyrins as Clinical Endogenous Markers for OATP1B.
    Feng S; Bo Q; Coleman HA; Charoin JE; Zhu M; Xiao J; Jin Y
    J Clin Pharmacol; 2021 Aug; 61(8):1027-1034. PubMed ID: 33460165
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.