BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

446 related articles for article (PubMed ID: 28584141)

  • 1. Multimechanistic Monoclonal Antibodies (MAbs) Targeting Staphylococcus aureus Alpha-Toxin and Clumping Factor A: Activity and Efficacy Comparisons of a MAb Combination and an Engineered Bispecific Antibody Approach.
    Tkaczyk C; Kasturirangan S; Minola A; Jones-Nelson O; Gunter V; Shi YY; Rosenthal K; Aleti V; Semenova E; Warrener P; Tabor D; Stover CK; Corti D; Rainey G; Sellman BR
    Antimicrob Agents Chemother; 2017 Aug; 61(8):. PubMed ID: 28584141
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting Alpha Toxin and ClfA with a Multimechanistic Monoclonal-Antibody-Based Approach for Prophylaxis of Serious Staphylococcus aureus Disease.
    Tkaczyk C; Hamilton MM; Sadowska A; Shi Y; Chang CS; Chowdhury P; Buonapane R; Xiao X; Warrener P; Mediavilla J; Kreiswirth B; Suzich J; Stover CK; Sellman BR
    mBio; 2016 Jun; 7(3):. PubMed ID: 27353753
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Characterization of alpha-toxin hla gene variants, alpha-toxin expression levels, and levels of antibody to alpha-toxin in hemodialysis and postsurgical patients with Staphylococcus aureus bacteremia.
    Sharma-Kuinkel BK; Wu Y; Tabor DE; Mok H; Sellman BR; Jenkins A; Yu L; Jafri HS; Rude TH; Ruffin F; Schell WA; Park LP; Yan Q; Thaden JT; Messina JA; Fowler VG; Esser MT
    J Clin Microbiol; 2015 Jan; 53(1):227-36. PubMed ID: 25392350
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Efficacy of a Multimechanistic Monoclonal Antibody Combination against Staphylococcus aureus Surgical Site Infections in Mice.
    Ortines RV; Wang Y; Liu H; Dikeman DA; Pinsker BL; Miller RJ; Kim SE; Ackerman NE; Rizkallah JF; Marcello LT; Cohen TS; Tkaczyk C; Sellman BR; Miller LS
    Antimicrob Agents Chemother; 2019 Aug; 63(8):. PubMed ID: 31138566
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of a protective monoclonal antibody recognizing Staphylococcus aureus MSCRAMM protein clumping factor A.
    Hall AE; Domanski PJ; Patel PR; Vernachio JH; Syribeys PJ; Gorovits EL; Johnson MA; Ross JM; Hutchins JT; Patti JM
    Infect Immun; 2003 Dec; 71(12):6864-70. PubMed ID: 14638774
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Preclinical Efficacy of Clumping Factor A in Prevention of Staphylococcus aureus Infection.
    Li X; Wang X; Thompson CD; Park S; Park WB; Lee JC
    mBio; 2016 Feb; 7(1):e02232-15. PubMed ID: 26838725
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protection of mice against Staphylococcus aureus infection by a recombinant protein ClfA-IsdB-Hlg as a vaccine candidate.
    Delfani S; Mohabati Mobarez A; Imani Fooladi AA; Amani J; Emaneini M
    Med Microbiol Immunol; 2016 Feb; 205(1):47-55. PubMed ID: 26155981
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Demonstration of the preclinical correlate of protection for Staphylococcus aureus clumping factor A in a murine model of infection.
    Scully IL; Timofeyeva Y; Keeney D; Matsuka YV; Severina E; McNeil LK; Nanra J; Hu G; Liberator PA; Jansen KU; Anderson AS
    Vaccine; 2015 Oct; 33(41):5452-5457. PubMed ID: 26319743
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Monoclonal antibodies neutralizing alpha-hemolysin, bicomponent leukocidins, and clumping factor A protected against
    Nguyen NTQ; Doan TNM; Sato K; Tkaczyk C; Sellman BR; Diep BA
    Front Immunol; 2023; 14():1260627. PubMed ID: 37781371
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Alanine Scanning Mutagenesis of the MEDI4893 (Suvratoxumab) Epitope Reduces Alpha Toxin Lytic Activity
    Tkaczyk C; Semenova E; Shi YY; Rosenthal K; Oganesyan V; Warrener P; Stover CK; Sellman BR
    Antimicrob Agents Chemother; 2018 Nov; 62(11):. PubMed ID: 30150481
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Staphylococcus aureus Alpha-Toxin Is Conserved among Diverse Hospital Respiratory Isolates Collected from a Global Surveillance Study and Is Neutralized by Monoclonal Antibody MEDI4893.
    Tabor DE; Yu L; Mok H; Tkaczyk C; Sellman BR; Wu Y; Oganesyan V; Slidel T; Jafri H; McCarthy M; Bradford P; Esser MT
    Antimicrob Agents Chemother; 2016 Sep; 60(9):5312-21. PubMed ID: 27324766
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Critical Role of Alpha-Toxin and Protective Effects of Its Neutralization by a Human Antibody in Acute Bacterial Skin and Skin Structure Infections.
    Le VT; Tkaczyk C; Chau S; Rao RL; Dip EC; Pereira-Franchi EP; Cheng L; Lee S; Koelkebeck H; Hilliard JJ; Yu XQ; Datta V; Nguyen V; Weiss W; Prokai L; O'Day T; Stover CK; Sellman BR; Diep BA
    Antimicrob Agents Chemother; 2016 Oct; 60(10):5640-8. PubMed ID: 27401576
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Improved Protection in a Rabbit Model of Community-Associated Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia upon Neutralization of Leukocidins in Addition to Alpha-Hemolysin.
    Diep BA; Le VT; Visram ZC; Rouha H; Stulik L; Dip EC; Nagy G; Nagy E
    Antimicrob Agents Chemother; 2016 Oct; 60(10):6333-40. PubMed ID: 27527081
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and evaluation of a conjugate vaccine composed of Staphylococcus aureus poly-N-acetyl-glucosamine and clumping factor A.
    Maira-Litrán T; Bentancor LV; Bozkurt-Guzel C; O'Malley JM; Cywes-Bentley C; Pier GB
    PLoS One; 2012; 7(9):e43813. PubMed ID: 22970144
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vivo mapping of a protective linear neutralizing epitope at the N-terminus of alpha hemolysin from Staphylococcus aureus.
    Oscherwitz J; Muñoz-Planillo R; Yu F; Núñez G; Cease KB
    Mol Immunol; 2014 Jul; 60(1):62-71. PubMed ID: 24769493
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A human monoclonal antibody targeting the conserved staphylococcal antigen IsaA protects mice against Staphylococcus aureus bacteremia.
    van den Berg S; Bonarius HP; van Kessel KP; Elsinga GS; Kooi N; Westra H; Bosma T; van der Kooi-Pol MM; Koedijk DG; Groen H; van Dijl JM; Buist G; Bakker-Woudenberg IA
    Int J Med Microbiol; 2015 Jan; 305(1):55-64. PubMed ID: 25466204
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Convergent Evolution of Neutralizing Antibodies to Staphylococcus aureus γ-Hemolysin C That Recognize an Immunodominant Primary Sequence-Dependent B-Cell Epitope.
    Hernandez DN; Tam K; Shopsin B; Radke EE; Law K; Cardozo T; Torres VJ; Silverman GJ
    mBio; 2020 Jun; 11(3):. PubMed ID: 32546616
    [No Abstract]   [Full Text] [Related]  

  • 18. c-di-GMP as a vaccine adjuvant enhances protection against systemic methicillin-resistant Staphylococcus aureus (MRSA) infection.
    Hu DL; Narita K; Hyodo M; Hayakawa Y; Nakane A; Karaolis DK
    Vaccine; 2009 Jul; 27(35):4867-73. PubMed ID: 19406185
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Five birds, one stone: neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody.
    Rouha H; Badarau A; Visram ZC; Battles MB; Prinz B; Magyarics Z; Nagy G; Mirkina I; Stulik L; Zerbs M; Jägerhofer M; Maierhofer B; Teubenbacher A; Dolezilkova I; Gross K; Banerjee S; Zauner G; Malafa S; Zmajkovic J; Maier S; Mabry R; Krauland E; Wittrup KD; Gerngross TU; Nagy E
    MAbs; 2015; 7(1):243-54. PubMed ID: 25523282
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Anti-alpha-toxin monoclonal antibody and antibiotic combination therapy improves disease outcome and accelerates healing in a Staphylococcus aureus dermonecrosis model.
    Hilliard JJ; Datta V; Tkaczyk C; Hamilton M; Sadowska A; Jones-Nelson O; O'Day T; Weiss WJ; Szarka S; Nguyen V; Prokai L; Suzich J; Stover CK; Sellman BR
    Antimicrob Agents Chemother; 2015 Jan; 59(1):299-309. PubMed ID: 25348518
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.