BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

340 related articles for article (PubMed ID: 28585384)

  • 1. Modeling the C9ORF72 repeat expansion mutation using human induced pluripotent stem cells.
    Selvaraj BT; Livesey MR; Chandran S
    Brain Pathol; 2017 Jul; 27(4):518-524. PubMed ID: 28585384
    [TBL] [Abstract][Full Text] [Related]  

  • 2. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
    Beckers J; Tharkeshwar AK; Van Damme P
    Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
    [TBL] [Abstract][Full Text] [Related]  

  • 3. C9orf72 Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
    Dafinca R; Scaber J; Ababneh N; Lalic T; Weir G; Christian H; Vowles J; Douglas AG; Fletcher-Jones A; Browne C; Nakanishi M; Turner MR; Wade-Martins R; Cowley SA; Talbot K
    Stem Cells; 2016 Aug; 34(8):2063-78. PubMed ID: 27097283
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Generation of a human induced pluripotent stem cell (iPSC) line (IBMS-iPSC-048-05) from a patient with ALS and parkinsonism having a hexanucleotide repeat expansion mutation in C9orf72 gene.
    Lin HY; Tsai LK; Cheng YC; Lu HE; Huang CY; Hsieh PCH; Lin CH
    Stem Cell Res; 2020 Apr; 44():101734. PubMed ID: 32151952
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD.
    Esanov R; Cabrera GT; Andrade NS; Gendron TF; Brown RH; Benatar M; Wahlestedt C; Mueller C; Zeier Z
    Mol Neurodegener; 2017 Jun; 12(1):46. PubMed ID: 28606110
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Generation of five induced pluripotent stem cells lines from four members of the same family carrying a C9orf72 repeat expansion and one wild-type member.
    Lattuada C; Santangelo S; Peverelli S; McGoldrick P; Rogaeva E; Zinman L; Haase G; Géli V; Silani V; Robertson J; Ratti A; Bossolasco P
    Stem Cell Res; 2023 Feb; 66():102998. PubMed ID: 36528014
    [TBL] [Abstract][Full Text] [Related]  

  • 7. UBQLN2-HSP70 axis reduces poly-Gly-Ala aggregates and alleviates behavioral defects in the C9ORF72 animal model.
    Zhang K; Wang A; Zhong K; Qi S; Wei C; Shu X; Tu WY; Xu W; Xia C; Xiao Y; Chen A; Bai L; Zhang J; Luo B; Wang W; Shen C
    Neuron; 2021 Jun; 109(12):1949-1962.e6. PubMed ID: 33991504
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stable transgenic C9orf72 zebrafish model key aspects of the ALS/FTD phenotype and reveal novel pathological features.
    Shaw MP; Higginbottom A; McGown A; Castelli LM; James E; Hautbergue GM; Shaw PJ; Ramesh TM
    Acta Neuropathol Commun; 2018 Nov; 6(1):125. PubMed ID: 30454072
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modeling key pathological features of frontotemporal dementia with C9ORF72 repeat expansion in iPSC-derived human neurons.
    Almeida S; Gascon E; Tran H; Chou HJ; Gendron TF; Degroot S; Tapper AR; Sellier C; Charlet-Berguerand N; Karydas A; Seeley WW; Boxer AL; Petrucelli L; Miller BL; Gao FB
    Acta Neuropathol; 2013 Sep; 126(3):385-99. PubMed ID: 23836290
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Human C9ORF72 Hexanucleotide Expansion Reproduces RNA Foci and Dipeptide Repeat Proteins but Not Neurodegeneration in BAC Transgenic Mice.
    Peters OM; Cabrera GT; Tran H; Gendron TF; McKeon JE; Metterville J; Weiss A; Wightman N; Salameh J; Kim J; Sun H; Boylan KB; Dickson D; Kennedy Z; Lin Z; Zhang YJ; Daughrity L; Jung C; Gao FB; Sapp PC; Horvitz HR; Bosco DA; Brown SP; de Jong P; Petrucelli L; Mueller C; Brown RH
    Neuron; 2015 Dec; 88(5):902-909. PubMed ID: 26637797
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction.
    Perkins EM; Burr K; Banerjee P; Mehta AR; Dando O; Selvaraj BT; Suminaite D; Nanda J; Henstridge CM; Gillingwater TH; Hardingham GE; Wyllie DJA; Chandran S; Livesey MR
    Mol Neurodegener; 2021 Mar; 16(1):13. PubMed ID: 33663561
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insights into C9ORF72-Related ALS/FTD from Drosophila and iPSC Models.
    Yuva-Aydemir Y; Almeida S; Gao FB
    Trends Neurosci; 2018 Jul; 41(7):457-469. PubMed ID: 29729808
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.
    Hao Z; Wang R; Ren H; Wang G
    Neurosci Bull; 2020 Sep; 36(9):1057-1070. PubMed ID: 32860626
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pathogenic Mechanisms and Therapy Development for C9orf72 Amyotrophic Lateral Sclerosis/Frontotemporal Dementia.
    Jiang J; Ravits J
    Neurotherapeutics; 2019 Oct; 16(4):1115-1132. PubMed ID: 31667754
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
    Shi Y; Lin S; Staats KA; Li Y; Chang WH; Hung ST; Hendricks E; Linares GR; Wang Y; Son EY; Wen X; Kisler K; Wilkinson B; Menendez L; Sugawara T; Woolwine P; Huang M; Cowan MJ; Ge B; Koutsodendris N; Sandor KP; Komberg J; Vangoor VR; Senthilkumar K; Hennes V; Seah C; Nelson AR; Cheng TY; Lee SJ; August PR; Chen JA; Wisniewski N; Hanson-Smith V; Belgard TG; Zhang A; Coba M; Grunseich C; Ward ME; van den Berg LH; Pasterkamp RJ; Trotti D; Zlokovic BV; Ichida JK
    Nat Med; 2018 Mar; 24(3):313-325. PubMed ID: 29400714
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD.
    Moore S; Alsop E; Lorenzini I; Starr A; Rabichow BE; Mendez E; Levy JL; Burciu C; Reiman R; Chew J; Belzil VV; W Dickson D; Robertson J; Staats KA; Ichida JK; Petrucelli L; Van Keuren-Jensen K; Sattler R
    Acta Neuropathol; 2019 Jul; 138(1):49-65. PubMed ID: 30945056
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair.
    Ababneh NA; Scaber J; Flynn R; Douglas A; Barbagallo P; Candalija A; Turner MR; Sims D; Dafinca R; Cowley SA; Talbot K
    Hum Mol Genet; 2020 Aug; 29(13):2200-2217. PubMed ID: 32504093
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Screening for the C9ORF72 repeat expansion in a greek frontotemporal dementia cohort.
    Kartanou C; Karadima G; Koutsis G; Breza M; Papageorgiou SG; Paraskevas GP; Kapaki E; Panas M
    Amyotroph Lateral Scler Frontotemporal Degener; 2018 Feb; 19(1-2):152-154. PubMed ID: 29166782
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The frequency of the C9orf72 expansion in a Brazilian population.
    Cintra VP; Bonadia LC; Andrade HMT; de Albuquerque M; Eusébio MF; de Oliveira DS; Claudino R; Gonçalves MVM; Teixeira AL; de Godoy Rousseff Prado L; de Souza LC; Dourado MET; Oliveira ASB; Tumas V; França MC; Marques W
    Neurobiol Aging; 2018 Jun; 66():179.e1-179.e4. PubMed ID: 29449030
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dipeptide repeat protein and TDP-43 pathology along the hypothalamic-pituitary axis in C9orf72 and non-C9orf72 ALS and FTLD-TDP cases.
    Dedeene L; Van Schoor E; Ospitalieri S; Ronisz A; Weishaupt JH; Otto M; Ludolph AC; Scheuerle A; Vandenberghe R; Van Damme P; Poesen K; Thal DR
    Acta Neuropathol; 2020 Nov; 140(5):777-781. PubMed ID: 32862270
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 17.