189 related articles for article (PubMed ID: 28591512)
1. Discovery of a Highly Selective Tankyrase Inhibitor Displaying Growth Inhibition Effects against a Diverse Range of Tumor Derived Cell Lines.
Thomson DW; Wagner AJ; Bantscheff M; Benson RE; Dittus L; Duempelfeld B; Drewes G; Krause J; Moore JT; Mueller K; Poeckel D; Rau C; Salzer E; Shewchuk L; Hopf C; Emery JG; Muelbaier M
J Med Chem; 2017 Jul; 60(13):5455-5471. PubMed ID: 28591512
[TBL] [Abstract][Full Text] [Related]
2. Development of novel dual binders as potent, selective, and orally bioavailable tankyrase inhibitors.
Hua Z; Bregman H; Buchanan JL; Chakka N; Guzman-Perez A; Gunaydin H; Huang X; Gu Y; Berry V; Liu J; Teffera Y; Huang L; Egge B; Emkey R; Mullady EL; Schneider S; Andrews PS; Acquaviva L; Dovey J; Mishra A; Newcomb J; Saffran D; Serafino R; Strathdee CA; Turci SM; Stanton M; Wilson C; Dimauro EF
J Med Chem; 2013 Dec; 56(24):10003-15. PubMed ID: 24294969
[TBL] [Abstract][Full Text] [Related]
3. Optimization of a Screening Hit toward M2912, an Oral Tankyrase Inhibitor with Antitumor Activity in Colorectal Cancer Models.
Buchstaller HP; Anlauf U; Dorsch D; Kögler S; Kuhn D; Lehmann M; Leuthner B; Lodholz S; Musil D; Radtki D; Rettig C; Ritzert C; Rohdich F; Schneider R; Wegener A; Weigt S; Wilkinson K; Esdar C
J Med Chem; 2021 Jul; 64(14):10371-10392. PubMed ID: 34255518
[TBL] [Abstract][Full Text] [Related]
4. Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors.
Di Micco S; Pulvirenti L; Bruno I; Terracciano S; Russo A; Vaccaro MC; Ruggiero D; Muccilli V; Cardullo N; Tringali C; Riccio R; Bifulco G
Bioorg Med Chem; 2018 Aug; 26(14):3953-3957. PubMed ID: 29934219
[TBL] [Abstract][Full Text] [Related]
5. Discovery and Optimization of 2-Arylquinazolin-4-ones into a Potent and Selective Tankyrase Inhibitor Modulating Wnt Pathway Activity.
Buchstaller HP; Anlauf U; Dorsch D; Kuhn D; Lehmann M; Leuthner B; Musil D; Radtki D; Ritzert C; Rohdich F; Schneider R; Esdar C
J Med Chem; 2019 Sep; 62(17):7897-7909. PubMed ID: 31381853
[TBL] [Abstract][Full Text] [Related]
6. Discovery of novel 2-piperidinol-3-(arylsulfonyl)quinoxalines as phosphoinositide 3-kinase α (PI3Kα) inhibitors.
Wu P; Su Y; Liu X; Yang B; He Q; Hu Y
Bioorg Med Chem; 2012 May; 20(9):2837-44. PubMed ID: 22480851
[TBL] [Abstract][Full Text] [Related]
7. AlCl3-mediated hydroarylation-heteroarylation in a single pot: a direct access to densely functionalized olefins of pharmacological interest.
Nakhi A; Archana S; Seerapu GP; Chennubhotla KS; Kumar KL; Kulkarni P; Haldar D; Pal M
Chem Commun (Camb); 2013 Jul; 49(56):6268-70. PubMed ID: 23732749
[TBL] [Abstract][Full Text] [Related]
8. Discovery of a class of novel tankyrase inhibitors that bind to both the nicotinamide pocket and the induced pocket.
Bregman H; Gunaydin H; Gu Y; Schneider S; Wilson C; DiMauro EF; Huang X
J Med Chem; 2013 Feb; 56(3):1341-5. PubMed ID: 23316926
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis and molecular docking study of novel quinoxalin-2(1H)-ones as anti-tumor active agents with inhibition of tyrosine kinase receptor and studying their cyclooxygenase-2 activity.
Galal SA; Khairat SH; Ragab FA; Abdelsamie AS; Ali MM; Soliman SM; Mortier J; Wolber G; El Diwani HI
Eur J Med Chem; 2014 Oct; 86():122-32. PubMed ID: 25147154
[TBL] [Abstract][Full Text] [Related]
10. Discovery of potent and selective nonplanar tankyrase inhibiting nicotinamide mimics.
Nkizinkiko Y; Suneel Kumar BVS; Jeankumar VU; Haikarainen T; Koivunen J; Madhuri C; Yogeeswari P; Venkannagari H; Obaji E; Pihlajaniemi T; Sriram D; Lehtiö L
Bioorg Med Chem; 2015 Aug; 23(15):4139-4149. PubMed ID: 26183543
[TBL] [Abstract][Full Text] [Related]
11. Design, synthesis and biological evaluation of dihydroquinoxalinone derivatives as BRD4 inhibitors.
Yang Y; Zhao L; Xu B; Yang L; Zhang J; Zhang H; Zhou J
Bioorg Chem; 2016 Oct; 68():236-44. PubMed ID: 27580186
[TBL] [Abstract][Full Text] [Related]
12. Targeting Wnt-driven cancers: Discovery of novel tankyrase inhibitors.
Ferri M; Liscio P; Carotti A; Asciutti S; Sardella R; Macchiarulo A; Camaioni E
Eur J Med Chem; 2017 Dec; 142():506-522. PubMed ID: 29107427
[TBL] [Abstract][Full Text] [Related]
13. Discovery of a Novel Triazolopyridine Derivative as a Tankyrase Inhibitor.
Ryu H; Nam KY; Kim HJ; Song JY; Hwang SG; Kim JS; Kim J; Ahn J
Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34298950
[TBL] [Abstract][Full Text] [Related]
14. Development and structural analysis of adenosine site binding tankyrase inhibitors.
Haikarainen T; Waaler J; Ignatev A; Nkizinkiko Y; Venkannagari H; Obaji E; Krauss S; Lehtiö L
Bioorg Med Chem Lett; 2016 Jan; 26(2):328-333. PubMed ID: 26706174
[TBL] [Abstract][Full Text] [Related]
15. Structure-based design and discovery of potent and selective KDM5 inhibitors.
Nie Z; Shi L; Lai C; O'Connell SM; Xu J; Stansfield RK; Hosfield DJ; Veal JM; Stafford JA
Bioorg Med Chem Lett; 2018 May; 28(9):1490-1494. PubMed ID: 29627262
[TBL] [Abstract][Full Text] [Related]
16. Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor.
Hu J; Wang Y; Li Y; Xu L; Cao D; Song S; Damaneh MS; Wang X; Meng T; Chen YL; Shen J; Miao Z; Xiong B
Eur J Med Chem; 2017 Sep; 137():176-195. PubMed ID: 28586718
[TBL] [Abstract][Full Text] [Related]
17. Discovery of potent DOT1L inhibitors by AlphaLISA based High Throughput Screening assay.
Song Y; Li L; Chen Y; Liu J; Xiao S; Lian F; Zhang N; Ding H; Zhang Y; Chen K; Jiang H; Zhang C; Liu YC; Chen S; Luo C
Bioorg Med Chem; 2018 May; 26(8):1751-1758. PubMed ID: 29534934
[TBL] [Abstract][Full Text] [Related]
18. Discovery of pyrrolospirooxindole derivatives as novel cyclin dependent kinase 4 (CDK4) inhibitors by catalyst-free, green approach.
Kamal A; Mahesh R; Nayak VL; Babu KS; Kumar GB; Shaik AB; Kapure JS; Alarifi A
Eur J Med Chem; 2016 Jan; 108():476-485. PubMed ID: 26708114
[TBL] [Abstract][Full Text] [Related]
19. A novel tankyrase small-molecule inhibitor suppresses APC mutation-driven colorectal tumor growth.
Lau T; Chan E; Callow M; Waaler J; Boggs J; Blake RA; Magnuson S; Sambrone A; Schutten M; Firestein R; Machon O; Korinek V; Choo E; Diaz D; Merchant M; Polakis P; Holsworth DD; Krauss S; Costa M
Cancer Res; 2013 May; 73(10):3132-44. PubMed ID: 23539443
[TBL] [Abstract][Full Text] [Related]
20. A novel yeast cell-based screen identifies flavone as a tankyrase inhibitor.
Yashiroda Y; Okamoto R; Hatsugai K; Takemoto Y; Goshima N; Saito T; Hamamoto M; Sugimoto Y; Osada H; Seimiya H; Yoshida M
Biochem Biophys Res Commun; 2010 Apr; 394(3):569-73. PubMed ID: 20214890
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]