298 related articles for article (PubMed ID: 28592587)
1. Linaclotide activates guanylate cyclase-C/cGMP/protein kinase-II-dependent trafficking of CFTR in the intestine.
Ahsan MK; Tchernychev B; Kessler MM; Solinga RM; Arthur D; Linde CI; Silos-Santiago I; Hannig G; Ameen NA
Physiol Rep; 2017 Jun; 5(11):. PubMed ID: 28592587
[TBL] [Abstract][Full Text] [Related]
2. STa and cGMP stimulate CFTR translocation to the surface of villus enterocytes in rat jejunum and is regulated by protein kinase G.
Golin-Bisello F; Bradbury N; Ameen N
Am J Physiol Cell Physiol; 2005 Sep; 289(3):C708-16. PubMed ID: 15872007
[TBL] [Abstract][Full Text] [Related]
3. MRP4 Modulation of the Guanylate Cyclase-C/cGMP Pathway: Effects on Linaclotide-Induced Electrolyte Secretion and cGMP Efflux.
Tchernychev B; Ge P; Kessler MM; Solinga RM; Wachtel D; Tobin JV; Thomas SR; Lunte CE; Fretzen A; Hannig G; Bryant AP; Kurtz CB; Currie MG; Silos-Santiago I
J Pharmacol Exp Ther; 2015 Oct; 355(1):48-56. PubMed ID: 26216942
[TBL] [Abstract][Full Text] [Related]
4. Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit.
Busby RW; Bryant AP; Bartolini WP; Cordero EA; Hannig G; Kessler MM; Mahajan-Miklos S; Pierce CM; Solinga RM; Sun LJ; Tobin JV; Kurtz CB; Currie MG
Eur J Pharmacol; 2010 Dec; 649(1-3):328-35. PubMed ID: 20863829
[TBL] [Abstract][Full Text] [Related]
5. Linaclotide-a novel secretagogue in the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation.
Sharma S; Sharma T; Dhingra R; Tomar P; Singh S; Malhotra M; Bhardwaj TR
Mini Rev Med Chem; 2013 Oct; 13(11):1685-90. PubMed ID: 24001336
[TBL] [Abstract][Full Text] [Related]
6. Linaclotide inhibits colonic nociceptors and relieves abdominal pain via guanylate cyclase-C and extracellular cyclic guanosine 3',5'-monophosphate.
Castro J; Harrington AM; Hughes PA; Martin CM; Ge P; Shea CM; Jin H; Jacobson S; Hannig G; Mann E; Cohen MB; MacDougall JE; Lavins BJ; Kurtz CB; Silos-Santiago I; Johnston JM; Currie MG; Blackshaw LA; Brierley SM
Gastroenterology; 2013 Dec; 145(6):1334-46.e1-11. PubMed ID: 23958540
[TBL] [Abstract][Full Text] [Related]
7. Deciphering ion transporters, kinases and PDZ-adaptor molecules that mediate guanylate cyclase C agonist-dependent intestinal fluid loss in vivo.
Liu Y; Tan Q; Riederer B; di Stefano G; Römermann D; Qian J; Reiner J; Seidler U
Biochem Pharmacol; 2020 Aug; 178():114040. PubMed ID: 32422138
[TBL] [Abstract][Full Text] [Related]
8. Evidence for the presence of cGMP-dependent protein kinase-II in human distal colon and in T84, the colonic cell line.
Selvaraj NG; Prasad R; Goldstein JL; Rao MC
Biochim Biophys Acta; 2000 Oct; 1498(1):32-43. PubMed ID: 11042348
[TBL] [Abstract][Full Text] [Related]
9. Guanylin in the human pancreas: a novel luminocrine regulatory pathway of electrolyte secretion via cGMP and CFTR in the ductal system.
Kulaksiz H; Schmid A; Hönscheid M; Eissele R; Klempnauer J; Cetin Y
Histochem Cell Biol; 2001 Feb; 115(2):131-45. PubMed ID: 11444148
[TBL] [Abstract][Full Text] [Related]
10. cGMP inhibition of type 3 phosphodiesterase is the major mechanism by which C-type natriuretic peptide activates CFTR in the shark rectal gland.
De Jonge HR; Tilly BC; Hogema BM; Pfau DJ; Kelley CA; Kelley MH; Melita AM; Morris MT; Viola RM; Forrest JN
Am J Physiol Cell Physiol; 2014 Feb; 306(4):C343-53. PubMed ID: 24259420
[TBL] [Abstract][Full Text] [Related]
11. Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins.
Pattison AM; Blomain ES; Merlino DJ; Wang F; Crissey MA; Kraft CL; Rappaport JA; Snook AE; Lynch JP; Waldman SA
Infect Immun; 2016 Oct; 84(10):3083-91. PubMed ID: 27481254
[TBL] [Abstract][Full Text] [Related]
12. Gastrointestinal pain: unraveling a novel endogenous pathway through uroguanylin/guanylate cyclase-C/cGMP activation.
Silos-Santiago I; Hannig G; Eutamene H; Ustinova EE; Bernier SG; Ge P; Graul C; Jacobson S; Jin H; Liong E; Kessler MM; Reza T; Rivers S; Shea C; Tchernychev B; Bryant AP; Kurtz CB; Bueno L; Pezzone MA; Currie MG
Pain; 2013 Sep; 154(9):1820-1830. PubMed ID: 23748116
[TBL] [Abstract][Full Text] [Related]
13. [Pharmacological and clinical profile of linaclotide (Linzess
Keto Y; Kosako M
Nihon Yakurigaku Zasshi; 2019; 153(6):289-298. PubMed ID: 31178535
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of Na
Tan Q; di Stefano G; Tan X; Renjie X; Römermann D; Talbot SR; Seidler UE
Br J Pharmacol; 2021 Mar; 178(5):1018-1036. PubMed ID: 33179259
[TBL] [Abstract][Full Text] [Related]
15. Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation.
Busby RW; Kessler MM; Bartolini WP; Bryant AP; Hannig G; Higgins CS; Solinga RM; Tobin JV; Wakefield JD; Kurtz CB; Currie MG
J Pharmacol Exp Ther; 2013 Jan; 344(1):196-206. PubMed ID: 23090647
[TBL] [Abstract][Full Text] [Related]
16. Bioactivity of Oral Linaclotide in Human Colorectum for Cancer Chemoprevention.
Weinberg DS; Lin JE; Foster NR; Della'Zanna G; Umar A; Seisler D; Kraft WK; Kastenberg DM; Katz LC; Limburg PJ; Waldman SA
Cancer Prev Res (Phila); 2017 Jun; 10(6):345-354. PubMed ID: 28396341
[TBL] [Abstract][Full Text] [Related]
17. Expression of the receptor guanylyl cyclase C and its ligands in reproductive tissues of the rat: a potential role for a novel signaling pathway in the epididymis.
Jaleel M; London RM; Eber SL; Forte LR; Visweswariah SS
Biol Reprod; 2002 Dec; 67(6):1975-80. PubMed ID: 12444076
[TBL] [Abstract][Full Text] [Related]
18. Chenodeoxycholic acid stimulates Cl(-) secretion via cAMP signaling and increases cystic fibrosis transmembrane conductance regulator phosphorylation in T84 cells.
Ao M; Sarathy J; Domingue J; Alrefai WA; Rao MC
Am J Physiol Cell Physiol; 2013 Aug; 305(4):C447-56. PubMed ID: 23761628
[TBL] [Abstract][Full Text] [Related]
19. The electrolyte/fluid secretion stimulatory peptides guanylin and uroguanylin and their common functional coupling proteins in the rat pancreas: a correlative study of expression and cell-specific localization.
Kulaksiz H; Cetin Y
Pancreas; 2002 Aug; 25(2):170-5. PubMed ID: 12142741
[TBL] [Abstract][Full Text] [Related]
20. Linaclotide improves gastrointestinal transit in cystic fibrosis mice by inhibiting sodium/hydrogen exchanger 3.
McHugh DR; Cotton CU; Moss FJ; Vitko M; Valerio DM; Kelley TJ; Hao S; Jafri A; Drumm ML; Boron WF; Stern RC; McBennett K; Hodges CA
Am J Physiol Gastrointest Liver Physiol; 2018 Nov; 315(5):G868-G878. PubMed ID: 30118317
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
