These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 28595015)

  • 21. Discovery of fused tricyclic core containing HCV NS5A inhibitors with pan-genotype activity.
    Yu W; Coburn CA; Yang DY; Meinke PT; Wong M; Rosenblum SB; Chen KX; Njoroge GF; Chen L; Dwyer MP; Jiang Y; Nair AG; Selyutin O; Tong L; Zeng Q; Zhong B; Ji T; Hu B; Agrawal S; Xia E; Zhai Y; Liu R; Kong R; Ingravallo P; Asante-Appiah E; Nomeir A; Fells J; Kozlowski JA
    Bioorg Med Chem Lett; 2016 Jul; 26(13):3158-3162. PubMed ID: 27180013
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Preparation and biological evaluation of 1'-cyano-2'-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors.
    Mish MR; Cho A; Kirschberg T; Xu J; Zonte CS; Fenaux M; Park Y; Babusis D; Feng JY; Ray AS; Kim CU
    Bioorg Med Chem Lett; 2014 Jul; 24(14):3092-5. PubMed ID: 24907145
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Discovery of silyl proline containing HCV NS5A inhibitors with pan-genotype activity: SAR development.
    Nair AG; Zeng Q; Selyutin O; Rosenblum SB; Jiang Y; Yang DY; Keertikar K; Zhou G; Dwyer MP; Kim SH; Shankar B; Yu W; Tong L; Chen L; Mazzola R; Caldwell J; Tang H; Allard ML; Buckle RN; Gauuan PJ; Holst CL; Martin GS; Naicker KP; Vellekoop S; Agrawal S; Liu R; Kong R; Ingravallo P; Xia E; Zhai Y; Nomeir A; Kozlowski JA
    Bioorg Med Chem Lett; 2016 Mar; 26(5):1475-9. PubMed ID: 26850003
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and anti-HCV activity of β-d-2'-deoxy-2'-α-chloro-2'-β-fluoro and β-d-2'-deoxy-2'-α-bromo-2'-β-fluoro nucleosides and their phosphoramidate prodrugs.
    Ovadia R; Khalil A; Li H; De Schutter C; Mengshetti S; Zhou S; Bassit L; Coats SJ; Amblard F; Schinazi RF
    Bioorg Med Chem; 2019 Feb; 27(4):664-676. PubMed ID: 30655167
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Discovery of velpatasvir (GS-5816): A potent pan-genotypic HCV NS5A inhibitor in the single-tablet regimens Vosevi
    Link JO; Taylor JG; Trejo-Martin A; Kato D; Katana AA; Krygowski ES; Yang ZY; Zipfel S; Cottell JJ; Bacon EM; Tran CV; Yang CY; Wang Y; Wang KW; Zhao G; Cheng G; Tian Y; Gong R; Lee YJ; Yu M; Gorman E; Mogalian E; Perry JK
    Bioorg Med Chem Lett; 2019 Aug; 29(16):2415-2427. PubMed ID: 31230974
    [TBL] [Abstract][Full Text] [Related]  

  • 26. 2-Heteroarylimino-5-arylidene-4-thiazolidinones as a new class of non-nucleoside inhibitors of HCV NS5B polymerase.
    Küçükgüzel I; Satılmış G; Gurukumar KR; Basu A; Tatar E; Nichols DB; Talele TT; Kaushik-Basu N
    Eur J Med Chem; 2013 Nov; 69():931-41. PubMed ID: 24161679
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Anti-hepatitis C virus activity of novel beta-d-2'-C-methyl-4'-azido pyrimidine nucleoside phosphoramidate prodrugs.
    Rondla R; Coats SJ; McBrayer TR; Grier J; Johns M; Tharnish PM; Whitaker T; Zhou L; Schinazi RF
    Antivir Chem Chemother; 2009 Oct; 20(2):99-106. PubMed ID: 19843980
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis and anti-HCV activity of a series of β-d-2'-deoxy-2'-dibromo nucleosides and their corresponding phosphoramidate prodrugs.
    Chen Z; Cox BD; Garnier-Amblard EC; McBrayer TR; Coats SJ; Schinazi RF; Amblard F
    Bioorg Med Chem Lett; 2017 Dec; 27(23):5296-5299. PubMed ID: 29066308
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl-7-deazapurine nucleosides, their phosphoramidate prodrugs and 5'-triphosphates.
    Shi J; Zhou L; Zhang H; McBrayer TR; Detorio MA; Johns M; Bassit L; Powdrill MH; Whitaker T; Coats SJ; Götte M; Schinazi RF
    Bioorg Med Chem Lett; 2011 Dec; 21(23):7094-8. PubMed ID: 22014549
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Discovery of 4'-azido-2'-deoxy-2'-C-methyl cytidine and prodrugs thereof: a potent inhibitor of Hepatitis C virus replication.
    Nilsson M; Kalayanov G; Winqvist A; Pinho P; Sund C; Zhou XX; Wähling H; Belfrage AK; Pelcman M; Agback T; Benckestock K; Wikström K; Boothee M; Lindqvist A; Rydegård C; Jonckers TH; Vandyck K; Raboisson P; Lin TI; Lachau-Durand S; de Kock H; Smith DB; Martin JA; Klumpp K; Simmen K; Vrang L; Terelius Y; Samuelsson B; Rosenquist S; Johansson NG
    Bioorg Med Chem Lett; 2012 May; 22(9):3265-8. PubMed ID: 22472694
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Discovery of the pan-genotypic hepatitis C virus NS3/4A protease inhibitor voxilaprevir (GS-9857): A component of Vosevi
    Taylor JG; Zipfel S; Ramey K; Vivian R; Schrier A; Karki KK; Katana A; Kato D; Kobayashi T; Martinez R; Sangi M; Siegel D; Tran CV; Yang ZY; Zablocki J; Yang CY; Wang Y; Wang K; Chan K; Barauskas O; Cheng G; Jin D; Schultz BE; Appleby T; Villaseñor AG; Link JO
    Bioorg Med Chem Lett; 2019 Aug; 29(16):2428-2436. PubMed ID: 31133531
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles.
    Court JJ; Poisson C; Ardzinski A; Bilimoria D; Chan L; Chandupatla K; Chauret N; Collier PN; Das SK; Denis F; Dorsch W; Iyer G; Lauffer D; L'Heureux L; Li P; Luisi BS; Mani N; Nanthakumar S; Nicolas O; Rao BG; Ronkin S; Selliah S; Shawgo RS; Tang Q; Waal ND; Yannopoulos CG; Green J
    J Med Chem; 2016 Jul; 59(13):6293-302. PubMed ID: 27366941
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Synthesis and biological evaluation of a novel β-D-2'-deoxy-2'-α-fluoro-2'-β-C-(fluoromethyl)uridine phosphoramidate prodrug for the treatment of hepatitis C virus infection.
    Li E; Wang Y; Yu W; Lv Z; Peng Y; Liu B; Li S; Ho W; Wang Q; Li H; Chang J
    Eur J Med Chem; 2018 Jan; 143():107-113. PubMed ID: 29172078
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Recent advances on the synthesis of hepatitis C virus NS5B RNA-dependent RNA-polymerase inhibitors.
    Zhao C; Wang Y; Ma S
    Eur J Med Chem; 2015 Sep; 102():188-214. PubMed ID: 26276434
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Nucleotide prodrugs of 2'-deoxy-2'-spirooxetane ribonucleosides as novel inhibitors of the HCV NS5B polymerase.
    Jonckers TH; Vandyck K; Vandekerckhove L; Hu L; Tahri A; Van Hoof S; Lin TI; Vijgen L; Berke JM; Lachau-Durand S; Stoops B; Leclercq L; Fanning G; Samuelsson B; Nilsson M; Rosenquist Å; Simmen K; Raboisson P
    J Med Chem; 2014 Mar; 57(5):1836-44. PubMed ID: 24345201
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Progress in the development of anti-hepatitis C virus nucleoside and nucleotide prodrugs.
    Madela K; McGuigan C
    Future Med Chem; 2012 Apr; 4(5):625-50. PubMed ID: 22458682
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Base-modified ribonucleosides as potential anti-hepatitis C virus agents.
    Ivanov AV; Smirnova OA; Golubeva NA; Ivanov MA; Tunitskaya VL; Shipitsyn AV; Alexandrova LA
    Nucleic Acids Symp Ser (Oxf); 2008; (52):619-20. PubMed ID: 18776532
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis and antiviral properties of novel 7-heterocyclic substituted 7-deaza-adenine nucleoside inhibitors of Hepatitis C NS5B polymerase.
    Di Francesco ME; Avolio S; Pompei M; Pesci S; Monteagudo E; Pucci V; Giuliano C; Fiore F; Rowley M; Summa V
    Bioorg Med Chem; 2012 Aug; 20(15):4801-11. PubMed ID: 22770556
    [TBL] [Abstract][Full Text] [Related]  

  • 39. 3'-Deoxy phosphoramidate dinucleosides as improved inhibitors of hepatitis C virus subgenomic replicon and NS5B polymerase activity.
    Priet S; Zlatev I; Barvik I; Geerts K; Leyssen P; Neyts J; Dutartre H; Canard B; Vasseur JJ; Morvan F; Alvarez K
    J Med Chem; 2010 Sep; 53(18):6608-17. PubMed ID: 20799693
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Hepatitis C virus nucleotide inhibitors PSI-352938 and PSI-353661 exhibit a novel mechanism of resistance requiring multiple mutations within replicon RNA.
    Lam AM; Espiritu C; Bansal S; Micolochick Steuer HM; Zennou V; Otto MJ; Furman PA
    J Virol; 2011 Dec; 85(23):12334-42. PubMed ID: 21957306
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.