203 related articles for article (PubMed ID: 28596000)
1. The Nrf2/GCH1/BH4 Axis Ameliorates Radiation-Induced Skin Injury by Modulating the ROS Cascade.
Xue J; Yu C; Sheng W; Zhu W; Luo J; Zhang Q; Yang H; Cao H; Wang W; Zhou J; Wu J; Cao P; Chen M; Ding WQ; Cao J; Zhang S
J Invest Dermatol; 2017 Oct; 137(10):2059-2068. PubMed ID: 28596000
[TBL] [Abstract][Full Text] [Related]
2. Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation.
McNeill E; Crabtree MJ; Sahgal N; Patel J; Chuaiphichai S; Iqbal AJ; Hale AB; Greaves DR; Channon KM
Free Radic Biol Med; 2015 Feb; 79():206-16. PubMed ID: 25451639
[TBL] [Abstract][Full Text] [Related]
3. A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice.
Chuaiphichai S; Crabtree MJ; Mcneill E; Hale AB; Trelfa L; Channon KM; Douglas G
Br J Pharmacol; 2017 Apr; 174(8):657-671. PubMed ID: 28128438
[TBL] [Abstract][Full Text] [Related]
4. Mast cell tetrahydrobiopterin contributes to itch in mice.
Zschiebsch K; Fischer C; Wilken-Schmitz A; Geisslinger G; Channon K; Watschinger K; Tegeder I
J Cell Mol Med; 2019 Feb; 23(2):985-1000. PubMed ID: 30450838
[TBL] [Abstract][Full Text] [Related]
5. Ionizing radiation induces BH
Yan T; Zhang T; Mu W; Qi Y; Guo S; Hu N; Zhao W; Zhang S; Wang Q; Shi L; Liu L
Biochem Pharmacol; 2020 Oct; 180():114102. PubMed ID: 32562786
[TBL] [Abstract][Full Text] [Related]
6. Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression.
Douglas G; Hale AB; Patel J; Chuaiphichai S; Al Haj Zen A; Rashbrook VS; Trelfa L; Crabtree MJ; McNeill E; Channon KM
Cardiovasc Res; 2018 Aug; 114(10):1385-1399. PubMed ID: 29596571
[TBL] [Abstract][Full Text] [Related]
7. Induction of vascular GTP-cyclohydrolase I and endogenous tetrahydrobiopterin synthesis protect against inflammation-induced endothelial dysfunction in human atherosclerosis.
Antoniades C; Cunnington C; Antonopoulos A; Neville M; Margaritis M; Demosthenous M; Bendall J; Hale A; Cerrato R; Tousoulis D; Bakogiannis C; Marinou K; Toutouza M; Vlachopoulos C; Leeson P; Stefanadis C; Karpe F; Channon KM
Circulation; 2011 Oct; 124(17):1860-70. PubMed ID: 21969008
[TBL] [Abstract][Full Text] [Related]
8. GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.
Tegeder I; Costigan M; Griffin RS; Abele A; Belfer I; Schmidt H; Ehnert C; Nejim J; Marian C; Scholz J; Wu T; Allchorne A; Diatchenko L; Binshtok AM; Goldman D; Adolph J; Sama S; Atlas SJ; Carlezon WA; Parsegian A; Lötsch J; Fillingim RB; Maixner W; Geisslinger G; Max MB; Woolf CJ
Nat Med; 2006 Nov; 12(11):1269-77. PubMed ID: 17057711
[TBL] [Abstract][Full Text] [Related]
9. Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
Alp NJ; McAteer MA; Khoo J; Choudhury RP; Channon KM
Arterioscler Thromb Vasc Biol; 2004 Mar; 24(3):445-50. PubMed ID: 14707037
[TBL] [Abstract][Full Text] [Related]
10. Endothelial cell-specific roles for tetrahydrobiopterin in myocardial function, cardiac hypertrophy, and response to myocardial ischemia-reperfusion injury.
Chuaiphichai S; Chu SM; Carnicer R; Kelly M; Bendall JK; Simon JN; Douglas G; Crabtree MJ; Casadei B; Channon KM
Am J Physiol Heart Circ Physiol; 2023 Apr; 324(4):H430-H442. PubMed ID: 36735402
[TBL] [Abstract][Full Text] [Related]
11. Cytokine-stimulated GTP cyclohydrolase I expression in endothelial cells requires coordinated activation of nuclear factor-kappaB and Stat1/Stat3.
Huang A; Zhang YY; Chen K; Hatakeyama K; Keaney JF
Circ Res; 2005 Feb; 96(2):164-71. PubMed ID: 15604419
[TBL] [Abstract][Full Text] [Related]
12. Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches.
Hussein D; Starr A; Heikal L; McNeill E; Channon KM; Brown PR; Sutton BJ; McDonnell JM; Nandi M
Br J Pharmacol; 2015 Aug; 172(16):4146-57. PubMed ID: 26014146
[TBL] [Abstract][Full Text] [Related]
13. Analgesia by inhibiting tetrahydrobiopterin synthesis.
Costigan M; Latremoliere A; Woolf CJ
Curr Opin Pharmacol; 2012 Feb; 12(1):92-9. PubMed ID: 22178186
[TBL] [Abstract][Full Text] [Related]
14. GCH1 attenuates cardiac autonomic nervous remodeling in canines with atrial-tachypacing via tetrahydrobiopterin pathway regulated by microRNA-206.
Wei J; Zhang Y; Li Z; Wang X; Chen L; Du J; Liu J; Liu J; Hou Y
Pacing Clin Electrophysiol; 2018 May; 41(5):459-471. PubMed ID: 29436714
[TBL] [Abstract][Full Text] [Related]
15. Oral administration of tetrahydrobiopterin attenuates testicular damage by reducing nitric oxide synthase activity in a cryptorchid mouse model.
Kondo Y; Ishikawa T; Yamaguchi K; Yada T; Fujisawa M
J Androl; 2008; 29(2):153-63. PubMed ID: 17978343
[TBL] [Abstract][Full Text] [Related]
16. Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
Adlam D; Herring N; Douglas G; De Bono JP; Li D; Danson EJ; Tatham A; Lu CJ; Jennings KA; Cragg SJ; Casadei B; Paterson DJ; Channon KM
Cardiovasc Res; 2012 Mar; 93(4):694-701. PubMed ID: 22241166
[TBL] [Abstract][Full Text] [Related]
17. GCH1, BH4 and pain.
Latremoliere A; Costigan M
Curr Pharm Biotechnol; 2011 Oct; 12(10):1728-41. PubMed ID: 21466440
[TBL] [Abstract][Full Text] [Related]
18. Tetrahydrobiopterin Attenuates DSS-evoked Colitis in Mice by Rebalancing Redox and Lipid Signalling.
Zschiebsch K; Fischer C; Pickert G; Häussler A; Radeke H; Grösch S; Ferreirós N; Geisslinger G; Werner ER; Tegeder I
J Crohns Colitis; 2016 Aug; 10(8):965-78. PubMed ID: 26928964
[TBL] [Abstract][Full Text] [Related]
19. Role of nuclear factor kappa B in cytokine-induced nitric oxide and tetrahydrobiopterin synthesis in rat neonatal cardiac myocytes.
Hattori Y; Nakanishi N; Kasai K
J Mol Cell Cardiol; 1997 Jun; 29(6):1585-92. PubMed ID: 9220344
[TBL] [Abstract][Full Text] [Related]
20. Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation.
Carnicer R; Hale AB; Suffredini S; Liu X; Reilly S; Zhang MH; Surdo NC; Bendall JK; Crabtree MJ; Lim GB; Alp NJ; Channon KM; Casadei B
Circ Res; 2012 Aug; 111(6):718-27. PubMed ID: 22798524
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]