120 related articles for article (PubMed ID: 28603987)
1. Pharmacophore Identification and Scaffold Exploration to Discover Novel, Potent, and Chemically Stable Inhibitors of Acid Ceramidase in Melanoma Cells.
Ortega JA; Arencibia JM; La Sala G; Borgogno M; Bauer I; Bono L; Braccia C; Armirotti A; Girotto S; Ganesan A; De Vivo M
J Med Chem; 2017 Jul; 60(13):5800-5815. PubMed ID: 28603987
[TBL] [Abstract][Full Text] [Related]
2. Novel off-target effect of tamoxifen--inhibition of acid ceramidase activity in cancer cells.
Morad SA; Levin JC; Tan SF; Fox TE; Feith DJ; Cabot MC
Biochim Biophys Acta; 2013 Dec; 1831(12):1657-64. PubMed ID: 23939396
[TBL] [Abstract][Full Text] [Related]
3. Acid Ceramidase in Melanoma: EXPRESSION, LOCALIZATION, AND EFFECTS OF PHARMACOLOGICAL INHIBITION.
Realini N; Palese F; Pizzirani D; Pontis S; Basit A; Bach A; Ganesan A; Piomelli D
J Biol Chem; 2016 Jan; 291(5):2422-34. PubMed ID: 26553872
[TBL] [Abstract][Full Text] [Related]
4. Benzoxazolone Carboxamides as Potent Acid Ceramidase Inhibitors: Synthesis and Structure-Activity Relationship (SAR) Studies.
Bach A; Pizzirani D; Realini N; Vozella V; Russo D; Penna I; Melzig L; Scarpelli R; Piomelli D
J Med Chem; 2015 Dec; 58(23):9258-72. PubMed ID: 26560855
[TBL] [Abstract][Full Text] [Related]
5. Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity.
Realini N; Solorzano C; Pagliuca C; Pizzirani D; Armirotti A; Luciani R; Costi MP; Bandiera T; Piomelli D
Sci Rep; 2013; 3():1035. PubMed ID: 23301156
[TBL] [Abstract][Full Text] [Related]
6. Acid ceramidase, an emerging target for anti-cancer and anti-angiogenesis.
Cho SM; Kwon HJ
Arch Pharm Res; 2019 Mar; 42(3):232-243. PubMed ID: 30661200
[TBL] [Abstract][Full Text] [Related]
7. Acid Ceramidase: A Novel Therapeutic Target in Cancer.
Vijayan Y; Lankadasari MB; Harikumar KB
Curr Top Med Chem; 2019; 19(17):1512-1520. PubMed ID: 30827244
[TBL] [Abstract][Full Text] [Related]
8. N-Metallocenoylsphingosines as targeted ceramidase inhibitors: Syntheses and antitumoral effects.
Rothemund M; Bär A; Klatt F; Weidler S; Köhler L; Unverzagt C; Kuhn CD; Schobert R
Bioorg Chem; 2020 Apr; 97():103703. PubMed ID: 32143017
[TBL] [Abstract][Full Text] [Related]
9. Activity-Based Imaging of Acid Ceramidase in Living Cells.
Ordóñez YF; Abad JL; Aseeri M; Casas J; Garcia V; Casasampere M; Schuchman EH; Levade T; Delgado A; Triola G; Fabrias G
J Am Chem Soc; 2019 May; 141(19):7736-7742. PubMed ID: 31030513
[TBL] [Abstract][Full Text] [Related]
10. Potential role of acid ceramidase in conversion of cytostatic to cytotoxic end-point in pancreatic cancer cells.
Morad SA; Messner MC; Levin JC; Abdelmageed N; Park H; Merrill AH; Cabot MC
Cancer Chemother Pharmacol; 2013 Mar; 71(3):635-45. PubMed ID: 23263160
[TBL] [Abstract][Full Text] [Related]
11. Discovery of a new class of highly potent inhibitors of acid ceramidase: synthesis and structure-activity relationship (SAR).
Pizzirani D; Pagliuca C; Realini N; Branduardi D; Bottegoni G; Mor M; Bertozzi F; Scarpelli R; Piomelli D; Bandiera T
J Med Chem; 2013 May; 56(9):3518-30. PubMed ID: 23614460
[TBL] [Abstract][Full Text] [Related]
12. Acid ceramidase controls apoptosis and increases autophagy in human melanoma cells treated with doxorubicin.
Lai M; Amato R; La Rocca V; Bilgin M; Freer G; Spezia P; Quaranta P; Piomelli D; Pistello M
Sci Rep; 2021 May; 11(1):11221. PubMed ID: 34045496
[TBL] [Abstract][Full Text] [Related]
13. The emergence of acid ceramidase as a therapeutic target for acute myeloid leukemia.
Tan SF; Pearson JM; Feith DJ; Loughran TP
Expert Opin Ther Targets; 2017 Jun; 21(6):583-590. PubMed ID: 28434262
[TBL] [Abstract][Full Text] [Related]
14. Identification of cystatin SA as a novel inhibitor of acid ceramidase.
Eliyahu E; Shtraizent N; He X; Chen D; Shalgi R; Schuchman EH
J Biol Chem; 2011 Oct; 286(41):35624-35633. PubMed ID: 21846728
[TBL] [Abstract][Full Text] [Related]
15. C6-ceramide and targeted inhibition of acid ceramidase induce synergistic decreases in breast cancer cell growth.
Flowers M; Fabriás G; Delgado A; Casas J; Abad JL; Cabot MC
Breast Cancer Res Treat; 2012 Jun; 133(2):447-58. PubMed ID: 21935601
[TBL] [Abstract][Full Text] [Related]
16. Molecular Mechanism of Inhibition of Acid Ceramidase by Carmofur.
Dementiev A; Joachimiak A; Nguyen H; Gorelik A; Illes K; Shabani S; Gelsomino M; Ahn EE; Nagar B; Doan N
J Med Chem; 2019 Jan; 62(2):987-992. PubMed ID: 30525581
[TBL] [Abstract][Full Text] [Related]
17. Benzoxazolone carboxamides: potent and systemically active inhibitors of intracellular acid ceramidase.
Pizzirani D; Bach A; Realini N; Armirotti A; Mengatto L; Bauer I; Girotto S; Pagliuca C; De Vivo M; Summa M; Ribeiro A; Piomelli D
Angew Chem Int Ed Engl; 2015 Jan; 54(2):485-9. PubMed ID: 25395373
[TBL] [Abstract][Full Text] [Related]
18. Ablation of Acid Ceramidase Impairs Autophagy and Mitochondria Activity in Melanoma Cells.
Lai M; La Rocca V; Amato R; Freer G; Costa M; Spezia PG; Quaranta P; Lombardo G; Piomelli D; Pistello M
Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33806766
[TBL] [Abstract][Full Text] [Related]
19. Design, Synthesis, and Biological Evaluation of a Series of Oxazolone Carboxamides as a Novel Class of Acid Ceramidase Inhibitors.
Caputo S; Di Martino S; Cilibrasi V; Tardia P; Mazzonna M; Russo D; Penna I; Summa M; Bertozzi SM; Realini N; Margaroli N; Migliore M; Ottonello G; Liu M; Lansbury P; Armirotti A; Bertorelli R; Ray SS; Skerlj R; Scarpelli R
J Med Chem; 2020 Dec; 63(24):15821-15851. PubMed ID: 33290061
[TBL] [Abstract][Full Text] [Related]
20. Cytotoxicity and acid ceramidase inhibitory activity of 2-substituted aminoethanol amides.
Bedia C; Canals D; Matabosch X; Harrak Y; Casas J; Llebaria A; Delgado A; Fabriás G
Chem Phys Lipids; 2008 Nov; 156(1-2):33-40. PubMed ID: 18760267
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
