108 related articles for article (PubMed ID: 28603989)
1. α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors.
Wu Y; Zhangsun D; Zhu X; Kaas Q; Zhangsun M; Harvey PJ; Craik DJ; McIntosh JM; Luo S
J Med Chem; 2017 Jul; 60(13):5826-5833. PubMed ID: 28603989
[TBL] [Abstract][Full Text] [Related]
2. Computational and Functional Mapping of Human and Rat α6β4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs.
Hone AJ; Kaas Q; Kearns I; Hararah F; Gajewiak J; Christensen S; Craik DJ; McIntosh JM
J Med Chem; 2021 Feb; 64(3):1685-1700. PubMed ID: 33523678
[TBL] [Abstract][Full Text] [Related]
3. Using Constellation Pharmacology to Characterize a Novel α-Conotoxin from
Neves JLB; Urcino C; Chase K; Dowell C; Hone AJ; Morgenstern D; Chua VM; Ramiro IBL; Imperial JS; Leavitt LS; Phan J; Fisher FA; Watkins M; Raghuraman S; Tun JO; Ueberheide BM; McIntosh JM; Vasconcelos V; Olivera BM; Gajewiak J
Mar Drugs; 2024 Feb; 22(3):. PubMed ID: 38535458
[TBL] [Abstract][Full Text] [Related]
4. Potency- and Selectivity-Enhancing Mutations of Conotoxins for Nicotinic Acetylcholine Receptors Can Be Predicted Using Accurate Free-Energy Calculations.
Katz D; DiMattia MA; Sindhikara D; Li H; Abraham N; Leffler AE
Mar Drugs; 2021 Jun; 19(7):. PubMed ID: 34202022
[TBL] [Abstract][Full Text] [Related]
5. Synthesis, Activity, and Application of Fluorescent Analogs of [D1G, Δ14Q]LvIC Targeting α6β4 Nicotinic Acetylcholine Receptor.
Pei S; Xu C; Tan Y; Wang M; Yu J; Zhangsun D; Zhu X; Luo S
Bioconjug Chem; 2023 Dec; 34(12):2194-2204. PubMed ID: 37748043
[TBL] [Abstract][Full Text] [Related]
6. αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype.
Zhangsun D; Zhu X; Kaas Q; Wu Y; Craik DJ; McIntosh JM; Luo S
Neuropharmacology; 2017 Dec; 127():243-252. PubMed ID: 28416445
[TBL] [Abstract][Full Text] [Related]
7. Basic Residues at Position 11 of α-Conotoxin LvIA Influence Subtype Selectivity between α3β2 and α3β4 Nicotinic Receptors via an Electrostatic Mechanism.
Haufe Y; Kuruva V; Samanani Z; Lokaj G; Kamnesky G; Shadamarshan P; Shahoei R; Katz D; Sampson JM; Pusch M; Brik A; Nicke A; Leffler AE
ACS Chem Neurosci; 2023 Dec; 14(24):4311-4322. PubMed ID: 38051211
[TBL] [Abstract][Full Text] [Related]
8. Effects of Cyclization on Activity and Stability of α-Conotoxin TxIB.
Li X; Wang S; Zhu X; Zhangsun D; Wu Y; Luo S
Mar Drugs; 2020 Mar; 18(4):. PubMed ID: 32235388
[TBL] [Abstract][Full Text] [Related]
9. Critical residue properties for potency and selectivity of α-Conotoxin RgIA towards α9α10 nicotinic acetylcholine receptors.
Huynh PN; Harvey PJ; Gajewiak J; Craik DJ; Michael McIntosh J
Biochem Pharmacol; 2020 Nov; 181():114124. PubMed ID: 32593612
[TBL] [Abstract][Full Text] [Related]
10. Ribbon α-Conotoxin KTM Exhibits Potent Inhibition of Nicotinic Acetylcholine Receptors.
Marquart LA; Turner MW; Warner LR; King MD; Groome JR; McDougal OM
Mar Drugs; 2019 Nov; 17(12):. PubMed ID: 31795126
[TBL] [Abstract][Full Text] [Related]
11. Molecular Regulation of α3β4 Nicotinic Acetylcholine Receptors by Lupeol in Cardiovascular System.
Eom S; Kim C; Yeom HD; Lee J; Lee S; Baek YB; Na J; Park SI; Kim GY; Lee CM; Lee JH
Int J Mol Sci; 2020 Jun; 21(12):. PubMed ID: 32570692
[TBL] [Abstract][Full Text] [Related]
12. Computational Design of α-Conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes.
Wu X; Hone AJ; Huang YH; Clark RJ; McIntosh JM; Kaas Q; Craik DJ
Chemistry; 2024 Feb; 30(7):e202302909. PubMed ID: 37910861
[TBL] [Abstract][Full Text] [Related]
13. Selective Penicillamine Substitution Enables Development of a Potent Analgesic Peptide that Acts through a Non-Opioid-Based Mechanism.
Gajewiak J; Christensen SB; Dowell C; Hararah F; Fisher F; Huynh PN; Olivera BM; McIntosh JM
J Med Chem; 2021 Jul; 64(13):9271-9278. PubMed ID: 34142837
[TBL] [Abstract][Full Text] [Related]
14. Synthetic α-conotoxin mutants as probes for studying nicotinic acetylcholine receptors and in the development of novel drug leads.
Armishaw CJ
Toxins (Basel); 2010 Jun; 2(6):1471-99. PubMed ID: 22069647
[TBL] [Abstract][Full Text] [Related]
15. Molecular Regulation of Betulinic Acid on α3β4 Nicotinic Acetylcholine Receptors.
Lee S; Jung W; Eom S; Yeom HD; Park HD; Lee JH
Molecules; 2021 May; 26(9):. PubMed ID: 34062829
[TBL] [Abstract][Full Text] [Related]
16. α-Conotoxins Enhance both the In Vivo Suppression of Ehrlich carcinoma Growth and In Vitro Reduction in Cell Viability Elicited by Cyclooxygenase and Lipoxygenase Inhibitors.
Osipov AV; Terpinskaya TI; Yanchanka T; Balashevich T; Zhmak MN; Tsetlin VI; Utkin YN
Mar Drugs; 2020 Apr; 18(4):. PubMed ID: 32272633
[TBL] [Abstract][Full Text] [Related]
17. Discovery of benzamide analogs as negative allosteric modulators of human neuronal nicotinic receptors: pharmacophore modeling and structure-activity relationship studies.
Yi B; Long S; González-Cestari TF; Henderson BJ; Pavlovicz RE; Werbovetz K; Li C; McKay DB
Bioorg Med Chem; 2013 Aug; 21(15):4730-43. PubMed ID: 23757208
[TBL] [Abstract][Full Text] [Related]
18. Cell surface localization of α3β4 nicotinic acetylcholine receptors is regulated by N-cadherin homotypic binding and actomyosin contractility.
Brusés JL
PLoS One; 2013; 8(4):e62435. PubMed ID: 23626818
[TBL] [Abstract][Full Text] [Related]
19. Dual Antagonism of α9α10 nAChR and GABA
Li X; Tae HS; Chen S; Yousuf A; Huang L; Zhang J; Jiang T; Adams DJ; Yu R
J Med Chem; 2024 Jan; 67(2):971-987. PubMed ID: 38217860
[TBL] [Abstract][Full Text] [Related]
20. Rational Design of Potent α-Conotoxin PeIA Analogues with Non-Natural Amino Acids for the Inhibition of Human α9α10 Nicotinic Acetylcholine Receptors.
Li T; Tae HS; Liang J; Zhang Z; Li X; Jiang T; Adams DJ; Yu R
Mar Drugs; 2024 Feb; 22(3):. PubMed ID: 38535451
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
