These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

453 related articles for article (PubMed ID: 28607487)

  • 61. Coupling ligand structure to specific conformational switches in the beta2-adrenoceptor.
    Yao X; Parnot C; Deupi X; Ratnala VR; Swaminath G; Farrens D; Kobilka B
    Nat Chem Biol; 2006 Aug; 2(8):417-22. PubMed ID: 16799554
    [TBL] [Abstract][Full Text] [Related]  

  • 62. Conformation guides molecular efficacy in docking screens of activated β-2 adrenergic G protein coupled receptor.
    Weiss DR; Ahn S; Sassano MF; Kleist A; Zhu X; Strachan R; Roth BL; Lefkowitz RJ; Shoichet BK
    ACS Chem Biol; 2013 May; 8(5):1018-26. PubMed ID: 23485065
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Ligand-specific interactions modulate kinetic, energetic, and mechanical properties of the human β2 adrenergic receptor.
    Zocher M; Fung JJ; Kobilka BK; Müller DJ
    Structure; 2012 Aug; 20(8):1391-402. PubMed ID: 22748765
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.
    Rasmussen SG; Choi HJ; Fung JJ; Pardon E; Casarosa P; Chae PS; Devree BT; Rosenbaum DM; Thian FS; Kobilka TS; Schnapp A; Konetzki I; Sunahara RK; Gellman SH; Pautsch A; Steyaert J; Weis WI; Kobilka BK
    Nature; 2011 Jan; 469(7329):175-80. PubMed ID: 21228869
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Structure-based simulations reveal concerted dynamics of GPCR activation.
    Leioatts N; Suresh P; Romo TD; Grossfield A
    Proteins; 2014 Oct; 82(10):2538-51. PubMed ID: 24889093
    [TBL] [Abstract][Full Text] [Related]  

  • 66. CHIP-MYTH: a novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β₂-adrenergic receptor.
    Kittanakom S; Barrios-Rodiles M; Petschnigg J; Arnoldo A; Wong V; Kotlyar M; Heisler LE; Jurisica I; Wrana JL; Nislow C; Stagljar I
    Biochem Biophys Res Commun; 2014 Mar; 445(4):746-56. PubMed ID: 24561123
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism.
    Dalton JA; Lans I; Giraldo J
    BMC Bioinformatics; 2015 Apr; 16(1):124. PubMed ID: 25902715
    [TBL] [Abstract][Full Text] [Related]  

  • 68. Ligand-dependent perturbation of the conformational ensemble for the GPCR β2 adrenergic receptor revealed by HDX.
    West GM; Chien EY; Katritch V; Gatchalian J; Chalmers MJ; Stevens RC; Griffin PR
    Structure; 2011 Oct; 19(10):1424-32. PubMed ID: 21889352
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Mechanism of β
    Liu X; Masoudi A; Kahsai AW; Huang LY; Pani B; Staus DP; Shim PJ; Hirata K; Simhal RK; Schwalb AM; Rambarat PK; Ahn S; Lefkowitz RJ; Kobilka B
    Science; 2019 Jun; 364(6447):1283-1287. PubMed ID: 31249059
    [TBL] [Abstract][Full Text] [Related]  

  • 70. S111N mutation in the helical domain of human Gs(alpha) reduces its GDP/GTP exchange rate.
    Brito M; Guzmán L; Romo X; Soto X; Hinrichs MV; Olate J
    J Cell Biochem; 2002; 85(3):615-20. PubMed ID: 11968001
    [TBL] [Abstract][Full Text] [Related]  

  • 71. GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.
    Rosenbaum DM; Cherezov V; Hanson MA; Rasmussen SG; Thian FS; Kobilka TS; Choi HJ; Yao XJ; Weis WI; Stevens RC; Kobilka BK
    Science; 2007 Nov; 318(5854):1266-73. PubMed ID: 17962519
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Detergent- and phospholipid-based reconstitution systems have differential effects on constitutive activity of G-protein-coupled receptors.
    Staus DP; Wingler LM; Pichugin D; Prosser RS; Lefkowitz RJ
    J Biol Chem; 2019 Sep; 294(36):13218-13223. PubMed ID: 31362983
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Agonist-induced conformational changes in bovine rhodopsin: insight into activation of G-protein-coupled receptors.
    Bhattacharya S; Hall SE; Vaidehi N
    J Mol Biol; 2008 Oct; 382(2):539-55. PubMed ID: 18638482
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Energy Landscapes Reveal Agonist Control of G Protein-Coupled Receptor Activation via Microswitches.
    Fleetwood O; Matricon P; Carlsson J; Delemotte L
    Biochemistry; 2020 Feb; 59(7):880-891. PubMed ID: 31999436
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Position of transmembrane helix 6 determines receptor G protein coupling specificity.
    Rose AS; Elgeti M; Zachariae U; Grubmüller H; Hofmann KP; Scheerer P; Hildebrand PW
    J Am Chem Soc; 2014 Aug; 136(32):11244-7. PubMed ID: 25046433
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Molecular dynamics simulations of the effect of the G-protein and diffusible ligands on the β2-adrenergic receptor.
    Goetz A; Lanig H; Gmeiner P; Clark T
    J Mol Biol; 2011 Dec; 414(4):611-23. PubMed ID: 22037586
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Structural insights into binding specificity, efficacy and bias of a β
    Masureel M; Zou Y; Picard LP; van der Westhuizen E; Mahoney JP; Rodrigues JPGLM; Mildorf TJ; Dror RO; Shaw DE; Bouvier M; Pardon E; Steyaert J; Sunahara RK; Weis WI; Zhang C; Kobilka BK
    Nat Chem Biol; 2018 Nov; 14(11):1059-1066. PubMed ID: 30327561
    [TBL] [Abstract][Full Text] [Related]  

  • 78. The effect of ligand efficacy on the formation and stability of a GPCR-G protein complex.
    Yao XJ; Vélez Ruiz G; Whorton MR; Rasmussen SG; DeVree BT; Deupi X; Sunahara RK; Kobilka B
    Proc Natl Acad Sci U S A; 2009 Jun; 106(23):9501-6. PubMed ID: 19470481
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Efficacy of the β₂-adrenergic receptor is determined by conformational equilibrium in the transmembrane region.
    Kofuku Y; Ueda T; Okude J; Shiraishi Y; Kondo K; Maeda M; Tsujishita H; Shimada I
    Nat Commun; 2012; 3():1045. PubMed ID: 22948827
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Allosteric Effect of Nanobody Binding on Ligand-Specific Active States of the β2 Adrenergic Receptor.
    Chen Y; Fleetwood O; Pérez-Conesa S; Delemotte L
    J Chem Inf Model; 2021 Dec; 61(12):6024-6037. PubMed ID: 34780174
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 23.