917 related articles for article (PubMed ID: 28608850)
21. Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer.
Kovacovicova K; Skolnaja M; Heinmaa M; Mistrik M; Pata P; Pata I; Bartek J; Vinciguerra M
Front Oncol; 2018; 8():459. PubMed ID: 30425964
[TBL] [Abstract][Full Text] [Related]
22. CCN1 promotes hepatic steatosis and inflammation in non-alcoholic steatohepatitis.
Ju L; Sun Y; Xue H; Chen L; Gu C; Shao J; Lu R; Luo X; Wei J; Ma X; Bian Z
Sci Rep; 2020 Feb; 10(1):3201. PubMed ID: 32081971
[TBL] [Abstract][Full Text] [Related]
23. Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors.
Zhu Y; Tchkonia T; Fuhrmann-Stroissnigg H; Dai HM; Ling YY; Stout MB; Pirtskhalava T; Giorgadze N; Johnson KO; Giles CB; Wren JD; Niedernhofer LJ; Robbins PD; Kirkland JL
Aging Cell; 2016 Jun; 15(3):428-35. PubMed ID: 26711051
[TBL] [Abstract][Full Text] [Related]
24. Involvement of G protein-coupled receptor kinase 2 (GRK2) in the development of non-alcoholic steatosis and steatohepatitis in mice and humans.
Cruces-Sande M; Vila-Bedmar R; Arcones AC; González-Rodríguez Á; Rada P; Gutiérrez-de-Juan V; Vargas-Castrillón J; Iruzubieta P; Sánchez-González C; Formentini L; Crespo J; García-Monzón C; Martínez-Chantar ML; Valverde ÁM; Mayor F; Murga C
Biochim Biophys Acta Mol Basis Dis; 2018 Dec; 1864(12):3655-3667. PubMed ID: 30261289
[TBL] [Abstract][Full Text] [Related]
25. Quercetin Enhances Ligand-induced Apoptosis in Senescent Idiopathic Pulmonary Fibrosis Fibroblasts and Reduces Lung Fibrosis In Vivo.
Hohmann MS; Habiel DM; Coelho AL; Verri WA; Hogaboam CM
Am J Respir Cell Mol Biol; 2019 Jan; 60(1):28-40. PubMed ID: 30109946
[TBL] [Abstract][Full Text] [Related]
26. The chemotherapeutic drug doxorubicin does not exacerbate p16
Postmus AC; Kruit JK; Eilers RE; Havinga R; Koster MH; Johmura Y; Nakanishi M; van de Sluis B; Jonker JW
Toxicol Appl Pharmacol; 2023 Jun; 468():116531. PubMed ID: 37088304
[TBL] [Abstract][Full Text] [Related]
27. Human Rotator Cuff Tears Reveal an Age-Dependent Increase in Markers of Cellular Senescence and Selective Removal of Senescent Cells With Dasatinib + Quercetin Increases Genetic Expression of COL1A1 In Vitro.
Hawthorne BC; Wellington IJ; Sabitsky JT; Murphy KV; Karsmarski OP; Thomas RO; LeVasseur MR; Mancini MR; Trudeau MT; Gulati S; McCarthy MBR; Cote MP; Xu M; Mazzocca AD
Arthroscopy; 2024 Jan; 40(1):34-44. PubMed ID: 37356505
[TBL] [Abstract][Full Text] [Related]
28. Cellular senescence mediates fibrotic pulmonary disease.
Schafer MJ; White TA; Iijima K; Haak AJ; Ligresti G; Atkinson EJ; Oberg AL; Birch J; Salmonowicz H; Zhu Y; Mazula DL; Brooks RW; Fuhrmann-Stroissnigg H; Pirtskhalava T; Prakash YS; Tchkonia T; Robbins PD; Aubry MC; Passos JF; Kirkland JL; Tschumperlin DJ; Kita H; LeBrasseur NK
Nat Commun; 2017 Feb; 8():14532. PubMed ID: 28230051
[TBL] [Abstract][Full Text] [Related]
29. Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype.
Coppé JP; Rodier F; Patil CK; Freund A; Desprez PY; Campisi J
J Biol Chem; 2011 Oct; 286(42):36396-403. PubMed ID: 21880712
[TBL] [Abstract][Full Text] [Related]
30. M2 kupffer cells promote hepatocyte senescence: an IL-6-dependent protective mechanism against alcoholic liver disease.
Wan J; Benkdane M; Alons E; Lotersztajn S; Pavoine C
Am J Pathol; 2014 Jun; 184(6):1763-72. PubMed ID: 24713392
[TBL] [Abstract][Full Text] [Related]
31. NIK links inflammation to hepatic steatosis by suppressing PPARα in alcoholic liver disease.
Li Y; Chen M; Zhou Y; Tang C; Zhang W; Zhong Y; Chen Y; Zhou H; Sheng L
Theranostics; 2020; 10(8):3579-3593. PubMed ID: 32206109
[No Abstract] [Full Text] [Related]
32. Cellular senescence in hepatocytes contributes to metabolic disturbances in NASH.
Bonnet L; Alexandersson I; Baboota RK; Kroon T; Oscarsson J; Smith U; Boucher J
Front Endocrinol (Lausanne); 2022; 13():957616. PubMed ID: 36072934
[TBL] [Abstract][Full Text] [Related]
33. Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy-Related Bone Loss.
Chandra A; Lagnado AB; Farr JN; Monroe DG; Park S; Hachfeld C; Tchkonia T; Kirkland JL; Khosla S; Passos JF; Pignolo RJ
J Bone Miner Res; 2020 Jun; 35(6):1119-1131. PubMed ID: 32023351
[TBL] [Abstract][Full Text] [Related]
34. Procyanidin B2 ameliorates free fatty acids-induced hepatic steatosis through regulating TFEB-mediated lysosomal pathway and redox state.
Su H; Li Y; Hu D; Xie L; Ke H; Zheng X; Chen W
Free Radic Biol Med; 2018 Oct; 126():269-286. PubMed ID: 30142454
[TBL] [Abstract][Full Text] [Related]
35. Dasatinib Plus Quercetin Alleviates Choroid Neovascularization by Reducing the Cellular Senescence Burden in the RPE-Choroid.
Wang Y; Tseng Y; Chen K; Chen K; Chen K; Huang Z; Mao Z; Li X
Invest Ophthalmol Vis Sci; 2023 Sep; 64(12):39. PubMed ID: 37750741
[TBL] [Abstract][Full Text] [Related]
36. CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis.
Capparelli C; Chiavarina B; Whitaker-Menezes D; Pestell TG; Pestell RG; Hulit J; Andò S; Howell A; Martinez-Outschoorn UE; Sotgia F; Lisanti MP
Cell Cycle; 2012 Oct; 11(19):3599-610. PubMed ID: 22935696
[TBL] [Abstract][Full Text] [Related]
37. Differential roles for cyclin-dependent kinase inhibitors p21 and p16 in the mechanisms of senescence and differentiation in human fibroblasts.
Stein GH; Drullinger LF; Soulard A; Dulić V
Mol Cell Biol; 1999 Mar; 19(3):2109-17. PubMed ID: 10022898
[TBL] [Abstract][Full Text] [Related]
38. Senolytic drugs, dasatinib and quercetin, attenuate adipose tissue inflammation, and ameliorate metabolic function in old age.
Islam MT; Tuday E; Allen S; Kim J; Trott DW; Holland WL; Donato AJ; Lesniewski LA
Aging Cell; 2023 Feb; 22(2):e13767. PubMed ID: 36637079
[TBL] [Abstract][Full Text] [Related]
39. Adipogenic changes of hepatocytes in a high-fat diet-induced fatty liver mice model and non-alcoholic fatty liver disease patients.
Pan X; Wang P; Luo J; Wang Z; Song Y; Ye J; Hou X
Endocrine; 2015 Apr; 48(3):834-47. PubMed ID: 25138963
[TBL] [Abstract][Full Text] [Related]
40. The role of hepassocin in the development of non-alcoholic fatty liver disease.
Wu HT; Lu FH; Ou HY; Su YC; Hung HC; Wu JS; Yang YC; Wu CL; Chang CJ
J Hepatol; 2013 Nov; 59(5):1065-72. PubMed ID: 23792031
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]