BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 28611043)

  • 21. Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1.
    Lu J; Chen M; Ren XR; Wang J; Lyerly HK; Barak L; Chen W
    PLoS One; 2013; 8(5):e63353. PubMed ID: 23671675
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hedgehog-stimulated chemotaxis is mediated by smoothened located outside the primary cilium.
    Bijlsma MF; Damhofer H; Roelink H
    Sci Signal; 2012 Aug; 5(238):ra60. PubMed ID: 22912493
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation.
    Jung B; Padula D; Burtscher I; Landerer C; Lutter D; Theis F; Messias AC; Geerlof A; Sattler M; Kremmer E; Boldt K; Ueffing M; Lickert H
    PLoS One; 2016; 11(2):e0149477. PubMed ID: 26901434
    [TBL] [Abstract][Full Text] [Related]  

  • 24. ARL13B promotes angiogenesis and glioma growth by activating VEGFA-VEGFR2 signaling.
    Chen L; Xie X; Wang T; Xu L; Zhai Z; Wu H; Deng L; Lu Q; Chen Z; Yang X; Lu H; Chen YG; Luo S
    Neuro Oncol; 2023 May; 25(5):871-885. PubMed ID: 36322624
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A novel protein encoded by circular SMO RNA is essential for Hedgehog signaling activation and glioblastoma tumorigenicity.
    Wu X; Xiao S; Zhang M; Yang L; Zhong J; Li B; Li F; Xia X; Li X; Zhou H; Liu D; Huang N; Yang X; Xiao F; Zhang N
    Genome Biol; 2021 Jan; 22(1):33. PubMed ID: 33446260
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Targeting class I histone deacetylases by the novel small molecule inhibitor 4SC-202 blocks oncogenic hedgehog-GLI signaling and overcomes smoothened inhibitor resistance.
    Gruber W; Peer E; Elmer DP; Sternberg C; Tesanovic S; Del Burgo P; Coni S; Canettieri G; Neureiter D; Bartz R; Kohlhof H; Vitt D; Aberger F
    Int J Cancer; 2018 Mar; 142(5):968-975. PubMed ID: 29055107
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Targeting Smoothened Sensitizes Gastric Cancer to Chemotherapy in Experimental Models.
    Ma H; Tian Y; Yu X
    Med Sci Monit; 2017 Mar; 23():1493-1500. PubMed ID: 28350784
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Mechanisms of Smoothened Regulation in Hedgehog Signaling.
    Zhang J; Liu Z; Jia J
    Cells; 2021 Aug; 10(8):. PubMed ID: 34440907
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The role of hedgehog signaling in gastric cancer: molecular mechanisms, clinical potential, and perspective.
    Xu Y; Song S; Wang Z; Ajani JA
    Cell Commun Signal; 2019 Nov; 17(1):157. PubMed ID: 31775795
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Impact of the Smoothened inhibitor, IPI-926, on smoothened ciliary localization and Hedgehog pathway activity.
    Peluso MO; Campbell VT; Harari JA; Tibbitts TT; Proctor JL; Whitebread N; Conley JM; White KF; Kutok JL; Read MA; McGovern K; Faia KL
    PLoS One; 2014; 9(3):e90534. PubMed ID: 24608250
    [TBL] [Abstract][Full Text] [Related]  

  • 31. MIRLET7BHG promotes hepatocellular carcinoma progression by activating hepatic stellate cells through exosomal SMO to trigger Hedgehog pathway.
    Xia Y; Zhen L; Li H; Wang S; Chen S; Wang C; Yang X
    Cell Death Dis; 2021 Mar; 12(4):326. PubMed ID: 33771969
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Discovery of [1,2,4]triazolo[4,3-a]pyridines as potent Smoothened inhibitors targeting the Hedgehog pathway with improved antitumor activity in vivo.
    Tian N; Wu H; Zhang H; Yang D; Lv L; Yang Z; Zhang T; Quan D; Zhou L; Xie Y; Xu Y; Wei N; Zhang J; Chen M; Schmitz JC; Tian Y; Wu S
    Bioorg Med Chem; 2020 Aug; 28(16):115584. PubMed ID: 32690258
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Cholesterol Modification of Smoothened Is Required for Hedgehog Signaling.
    Xiao X; Tang JJ; Peng C; Wang Y; Fu L; Qiu ZP; Xiong Y; Yang LF; Cui HW; He XL; Yin L; Qi W; Wong CC; Zhao Y; Li BL; Qiu WW; Song BL
    Mol Cell; 2017 Apr; 66(1):154-162.e10. PubMed ID: 28344083
    [TBL] [Abstract][Full Text] [Related]  

  • 34. ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic.
    Wang J; Zhang Y; Huang WJ; Yang J; Tang WG; Huang TM; Tan WF
    Acta Pharmacol Sin; 2021 Jun; 42(6):1005-1013. PubMed ID: 32855528
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Smoothened loss is a characteristic of neuroendocrine prostate cancer.
    Wang L; Li H; Li Z; Li M; Tang Q; Wu C; Lu Z
    Prostate; 2021 Jun; 81(9):508-520. PubMed ID: 33955576
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Smoothened oligomerization/higher order clustering in lipid rafts is essential for high Hedgehog activity transduction.
    Shi D; Lv X; Zhang Z; Yang X; Zhou Z; Zhang L; Zhao Y
    J Biol Chem; 2013 May; 288(18):12605-14. PubMed ID: 23532857
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Drosophila Vps36 regulates Smo trafficking in Hedgehog signaling.
    Yang X; Mao F; Lv X; Zhang Z; Fu L; Lu Y; Wu W; Zhou Z; Zhang L; Zhao Y
    J Cell Sci; 2013 Sep; 126(Pt 18):4230-8. PubMed ID: 23843610
    [TBL] [Abstract][Full Text] [Related]  

  • 38. PAR1 participates in the ability of multidrug resistance and tumorigenesis by controlling Hippo-YAP pathway.
    Fujimoto D; Ueda Y; Hirono Y; Goi T; Yamaguchi A
    Oncotarget; 2015 Oct; 6(33):34788-99. PubMed ID: 26431277
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Ciliary smoothened-mediated noncanonical hedgehog signaling promotes tubulin acetylation.
    Lee H; Ko HW
    Biochem Biophys Res Commun; 2016 Nov; 480(4):574-579. PubMed ID: 27793670
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila.
    Li S; Chen Y; Shi Q; Yue T; Wang B; Jiang J
    PLoS Biol; 2012 Jan; 10(1):e1001239. PubMed ID: 22253574
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.