These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 28613814)

  • 1. 2-Chloropropionamide As a Low-Reactivity Electrophile for Irreversible Small-Molecule Probe Identification.
    Allimuthu D; Adams DJ
    ACS Chem Biol; 2017 Aug; 12(8):2124-2131. PubMed ID: 28613814
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase.
    Ge J; Zhang CJ; Li L; Chong LM; Wu X; Hao P; Sze SK; Yao SQ
    ACS Chem Biol; 2013 Nov; 8(11):2577-85. PubMed ID: 24070012
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel Protein Disulfide Isomerase Inhibitor with Anticancer Activity in Multiple Myeloma.
    Vatolin S; Phillips JG; Jha BK; Govindgari S; Hu J; Grabowski D; Parker Y; Lindner DJ; Zhong F; Distelhorst CW; Smith MR; Cotta C; Xu Y; Chilakala S; Kuang RR; Tall S; Reu FJ
    Cancer Res; 2016 Jun; 76(11):3340-50. PubMed ID: 27197150
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 1,3,5-Triazine as a modular scaffold for covalent inhibitors with streamlined target identification.
    Banerjee R; Pace NJ; Brown DR; Weerapana E
    J Am Chem Soc; 2013 Feb; 135(7):2497-500. PubMed ID: 23379904
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment.
    Xu S; Butkevich AN; Yamada R; Zhou Y; Debnath B; Duncan R; Zandi E; Petasis NA; Neamati N
    Proc Natl Acad Sci U S A; 2012 Oct; 109(40):16348-53. PubMed ID: 22988091
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A small molecule inhibits protein disulfide isomerase and triggers the chemosensitization of cancer cells.
    Eirich J; Braig S; Schyschka L; Servatius P; Hoffmann J; Hecht S; Fulda S; Zahler S; Antes I; Kazmaier U; Sieber SA; Vollmar AM
    Angew Chem Int Ed Engl; 2014 Nov; 53(47):12960-5. PubMed ID: 25256790
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of new peptide amides as selective cathepsin L inhibitors: the first step towards selective irreversible inhibitors?
    Torkar A; Lenarčič B; Lah T; Dive V; Devel L
    Bioorg Med Chem Lett; 2013 May; 23(10):2968-73. PubMed ID: 23562595
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An Oculus to Profile and Probe Target Engagement In Vivo: How T-REX Was Born and Its Evolution into G-REX.
    Long MJC; Rogg C; Aye Y
    Acc Chem Res; 2021 Feb; 54(3):618-631. PubMed ID: 33228351
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of 4,4'-Dipyridylsulfide Analogs as "Switchable Electrophiles" for Covalent Inhibition.
    Ahn YC; May VK; Bedford GC; Tuley AA; Fast W
    ACS Chem Biol; 2021 Feb; 16(2):264-269. PubMed ID: 33492128
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of sesquiterpene-inspired derivatives designed for covalent binding and their inhibition of the NF-κB pathway.
    Duplan V; Serba C; Garcia J; Valot G; Barluenga S; Hoerlé M; Cuendet M; Winssinger N
    Org Biomol Chem; 2014 Jan; 12(2):370-5. PubMed ID: 24263232
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Covalent Inhibition by a Natural Product-Inspired Latent Electrophile.
    Byun DP; Ritchie J; Jung Y; Holewinski R; Kim HR; Tagirasa R; Ivanic J; Weekley CM; Parker MW; Andresson T; Yoo E
    J Am Chem Soc; 2023 May; 145(20):11097-11109. PubMed ID: 37183434
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IRAK-4 inhibitors. Part 1: a series of amides.
    Buckley GM; Gowers L; Higueruelo AP; Jenkins K; Mack SR; Morgan T; Parry DM; Pitt WR; Rausch O; Richard MD; Sabin V; Fraser JL
    Bioorg Med Chem Lett; 2008 Jun; 18(11):3211-4. PubMed ID: 18474425
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Confirming target engagement for reversible inhibitors in vivo by kinetically tuned activity-based probes.
    Adibekian A; Martin BR; Chang JW; Hsu KL; Tsuboi K; Bachovchin DA; Speers AE; Brown SJ; Spicer T; Fernandez-Vega V; Ferguson J; Hodder PS; Rosen H; Cravatt BF
    J Am Chem Soc; 2012 Jun; 134(25):10345-8. PubMed ID: 22690931
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A high-throughput turbidometric assay for screening inhibitors of Leishmania major protein disulfide isomerase.
    Ben Khalaf N; De Muylder G; Ratnam J; Kean-Hooi Ang K; Arkin M; McKerrow J; Chenik M
    J Biomol Screen; 2011 Jun; 16(5):545-51. PubMed ID: 21441416
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of a small molecule PDI inhibitor that inhibits reduction of HIV-1 envelope glycoprotein gp120.
    Khan MM; Simizu S; Lai NS; Kawatani M; Shimizu T; Osada H
    ACS Chem Biol; 2011 Mar; 6(3):245-51. PubMed ID: 21121641
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and structure-activity relationship of indole-3-glyoxylamide libraries possessing highly potent activity in a cell line model of prion disease.
    Thompson MJ; Borsenberger V; Louth JC; Judd KE; Chen B
    J Med Chem; 2009 Dec; 52(23):7503-11. PubMed ID: 19842664
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of small molecules targeting the pseudokinase Her3.
    Lim SM; Xie T; Westover KD; Ficarro SB; Tae HS; Gurbani D; Sim T; Marto JA; Jänne PA; Crews CM; Gray NS
    Bioorg Med Chem Lett; 2015 Aug; 25(16):3382-9. PubMed ID: 26094118
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aryl amide small-molecule inhibitors of microRNA miR-21 function.
    Naro Y; Thomas M; Stephens MD; Connelly CM; Deiters A
    Bioorg Med Chem Lett; 2015 Nov; 25(21):4793-4796. PubMed ID: 26220158
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein disulfide isomerase as a novel target for cyclopentenone prostaglandins: implications for hypoxic ischemic injury.
    Liu H; Chen J; Li W; Rose ME; Shinde SN; Balasubramani M; Uechi GT; Mutus B; Graham SH; Hickey RW
    FEBS J; 2015 May; 282(10):2045-59. PubMed ID: 25754985
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Challenges in the evaluation of thiol-reactive inhibitors of human protein disulfide Isomerase.
    Foster CK; Thorpe C
    Free Radic Biol Med; 2017 Jul; 108():741-749. PubMed ID: 28465261
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.