501 related articles for article (PubMed ID: 28614718)
1. SIRT5 Desuccinylates and Activates Pyruvate Kinase M2 to Block Macrophage IL-1β Production and to Prevent DSS-Induced Colitis in Mice.
Wang F; Wang K; Xu W; Zhao S; Ye D; Wang Y; Xu Y; Zhou L; Chu Y; Zhang C; Qin X; Yang P; Yu H
Cell Rep; 2017 Jun; 19(11):2331-2344. PubMed ID: 28614718
[TBL] [Abstract][Full Text] [Related]
2. Desuccinylation of pyruvate kinase M2 by SIRT5 contributes to antioxidant response and tumor growth.
Xiangyun Y; Xiaomin N; Linping G; Yunhua X; Ziming L; Yongfeng Y; Zhiwei C; Shun L
Oncotarget; 2017 Jan; 8(4):6984-6993. PubMed ID: 28036303
[TBL] [Abstract][Full Text] [Related]
3. Pyruvate kinase M2 regulates Hif-1α activity and IL-1β induction and is a critical determinant of the warburg effect in LPS-activated macrophages.
Palsson-McDermott EM; Curtis AM; Goel G; Lauterbach MA; Sheedy FJ; Gleeson LE; van den Bosch MW; Quinn SR; Domingo-Fernandez R; Johnston DG; Jiang JK; Israelsen WJ; Keane J; Thomas C; Clish C; Vander Heiden M; Xavier RJ; O'Neill LA
Cell Metab; 2015 Jan; 21(1):65-80. PubMed ID: 25565206
[TBL] [Abstract][Full Text] [Related]
4. PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation.
Xie M; Yu Y; Kang R; Zhu S; Yang L; Zeng L; Sun X; Yang M; Billiar TR; Wang H; Cao L; Jiang J; Tang D
Nat Commun; 2016 Oct; 7():13280. PubMed ID: 27779186
[TBL] [Abstract][Full Text] [Related]
5. Functional skewing of TRIM21-SIRT5 interplay dictates IL-1β production in DSS-induced colitis.
Yao P; Chen T; Jiang P; Li L; Du W
EMBO Rep; 2022 Sep; 23(9):e54391. PubMed ID: 35770730
[TBL] [Abstract][Full Text] [Related]
6. Deoxyelephantopin decreases the release of inflammatory cytokines in macrophage associated with attenuation of aerobic glycolysis via modulation of PKM2.
Pan L; Hu L; Zhang L; Xu H; Chen Y; Bian Q; Zhu A; Wu H
Int Immunopharmacol; 2020 Feb; 79():106048. PubMed ID: 31863924
[TBL] [Abstract][Full Text] [Related]
7. Malt1 blocks IL-1β production by macrophages in vitro and limits dextran sodium sulfate-induced intestinal inflammation in vivo.
Monajemi M; Pang YCF; Bjornson S; Menzies SC; van Rooijen N; Sly LM
J Leukoc Biol; 2018 Sep; 104(3):557-572. PubMed ID: 29901822
[TBL] [Abstract][Full Text] [Related]
8. Sulforaphane diminishes moonlighting of pyruvate kinase M2 and interleukin 1β expression in M1 (LPS) macrophages.
Bahiraii S; Brenner M; Yan F; Weckwerth W; Heiss EH
Front Immunol; 2022; 13():935692. PubMed ID: 35983049
[TBL] [Abstract][Full Text] [Related]
9. Lactylation of PKM2 Suppresses Inflammatory Metabolic Adaptation in Pro-inflammatory Macrophages.
Wang J; Yang P; Yu T; Gao M; Liu D; Zhang J; Lu C; Chen X; Zhang X; Liu Y
Int J Biol Sci; 2022; 18(16):6210-6225. PubMed ID: 36439872
[TBL] [Abstract][Full Text] [Related]
10. Activator-Mediated Pyruvate Kinase M2 Activation Contributes to Endotoxin Tolerance by Promoting Mitochondrial Biogenesis.
Yi Z; Wu Y; Zhang W; Wang T; Gong J; Cheng Y; Miao C
Front Immunol; 2020; 11():595316. PubMed ID: 33542713
[TBL] [Abstract][Full Text] [Related]
11. Pyruvate kinase M2 accelerates pro-inflammatory cytokine secretion and cell proliferation induced by lipopolysaccharide in colorectal cancer.
Yang P; Li Z; Li H; Lu Y; Wu H; Li Z
Cell Signal; 2015 Jul; 27(7):1525-32. PubMed ID: 25778902
[TBL] [Abstract][Full Text] [Related]
12. Pyruvate Kinase M2 Promotes Expression of Proinflammatory Mediators in House Dust Mite-Induced Allergic Airways Disease.
van de Wetering C; Aboushousha R; Manuel AM; Chia SB; Erickson C; MacPherson MB; van der Velden JL; Anathy V; Dixon AE; Irvin CG; Poynter ME; van der Vliet A; Wouters EFM; Reynaert NL; Janssen-Heininger YMW
J Immunol; 2020 Feb; 204(4):763-774. PubMed ID: 31924651
[TBL] [Abstract][Full Text] [Related]
13. Shikonin ameliorated mice colitis by inhibiting dimerization and tetramerization of PKM2 in macrophages.
Huang B; Wang Q; Jiang L; Lu S; Li C; Xu C; Wang C; Zhang E; Zhang X
Front Pharmacol; 2022; 13():926945. PubMed ID: 36059938
[TBL] [Abstract][Full Text] [Related]
14. Galectin-3 Plays an Important Pro-inflammatory Role in the Induction Phase of Acute Colitis by Promoting Activation of NLRP3 Inflammasome and Production of IL-1β in Macrophages.
Simovic Markovic B; Nikolic A; Gazdic M; Bojic S; Vucicevic L; Kosic M; Mitrovic S; Milosavljevic M; Besra G; Trajkovic V; Arsenijevic N; Lukic ML; Volarevic V
J Crohns Colitis; 2016 May; 10(5):593-606. PubMed ID: 26786981
[TBL] [Abstract][Full Text] [Related]
15. Lycium barbarum Polysaccharide Antagonizes LPS-Induced Inflammation by Altering the Glycolysis and Differentiation of Macrophages by Triggering the Degradation of PKM2.
Ding H; Wang JJ; Zhang XY; Yin L; Feng T
Biol Pharm Bull; 2021 Mar; 44(3):379-388. PubMed ID: 33390389
[TBL] [Abstract][Full Text] [Related]
16. Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.
Bauer C; Duewell P; Mayer C; Lehr HA; Fitzgerald KA; Dauer M; Tschopp J; Endres S; Latz E; Schnurr M
Gut; 2010 Sep; 59(9):1192-9. PubMed ID: 20442201
[TBL] [Abstract][Full Text] [Related]
17. Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia.
Li M; Lu H; Wang X; Duan C; Zhu X; Zhang Y; Ge X; Ji F; Wang X; Su J; Zhang D
Mol Immunol; 2021 Dec; 140():250-266. PubMed ID: 34798593
[TBL] [Abstract][Full Text] [Related]
18. The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease.
Shirai T; Nazarewicz RR; Wallis BB; Yanes RE; Watanabe R; Hilhorst M; Tian L; Harrison DG; Giacomini JC; Assimes TL; Goronzy JJ; Weyand CM
J Exp Med; 2016 Mar; 213(3):337-54. PubMed ID: 26926996
[TBL] [Abstract][Full Text] [Related]
19. Glutamine mitigates murine burn sepsis by supporting macrophage M2 polarization through repressing the SIRT5-mediated desuccinylation of pyruvate dehydrogenase.
Zhu Y; Chen X; Lu Y; Xia L; Fan S; Huang Q; Liu X; Peng X
Burns Trauma; 2022; 10():tkac041. PubMed ID: 36601059
[TBL] [Abstract][Full Text] [Related]
20. Sirtuin 5-Mediated Lysine Desuccinylation Protects Mitochondrial Metabolism Following Subarachnoid Hemorrhage in Mice.
Xiao ZP; Lv T; Hou PP; Manaenko A; Liu Y; Jin Y; Gao L; Jia F; Tian Y; Li P; Zhang JH; Hu Q; Zhang X
Stroke; 2021 Dec; 52(12):4043-4053. PubMed ID: 34807744
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
