BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 28615518)

  • 1. Estrogen-activated MDM2 disrupts mammary tissue architecture through a p53-independent pathway.
    Kundu N; Brekman A; Kim JY; Xiao G; Gao C; Bargonetti J
    Oncotarget; 2017 Jul; 8(29):47916-47930. PubMed ID: 28615518
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A p53-independent role of Mdm2 in estrogen-mediated activation of breast cancer cell proliferation.
    Brekman A; Singh KE; Polotskaia A; Kundu N; Bargonetti J
    Breast Cancer Res; 2011 Jan; 13(1):R3. PubMed ID: 21223569
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Epithelial cell-derived periostin functions as a tumor suppressor in gastric cancer through stabilizing p53 and E-cadherin proteins via the Rb/E2F1/p14ARF/Mdm2 signaling pathway.
    Lv H; Liu R; Fu J; Yang Q; Shi J; Chen P; Ji M; Shi B; Hou P
    Cell Cycle; 2014; 13(18):2962-74. PubMed ID: 25486483
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Context-dependent roles of MDMX (MDM4) and MDM2 in breast cancer proliferation and circulating tumor cells.
    Gao C; Xiao G; Piersigilli A; Gou J; Ogunwobi O; Bargonetti J
    Breast Cancer Res; 2019 Jan; 21(1):5. PubMed ID: 30642351
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The cholesterol metabolite 27-hydroxycholesterol regulates p53 activity and increases cell proliferation via MDM2 in breast cancer cells.
    Raza S; Ohm JE; Dhasarathy A; Schommer J; Roche C; Hammer KD; Ghribi O
    Mol Cell Biochem; 2015 Dec; 410(1-2):187-95. PubMed ID: 26350565
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1.
    Reuther C; Heinzle V; Nölting S; Herterich S; Hahner S; Halilovic E; Jeay S; Wuerthner JU; Aristizabal Prada ET; Spöttl G; Maurer J; Auernhammer CJ
    Neuroendocrinology; 2018; 106(1):1-19. PubMed ID: 27871087
    [TBL] [Abstract][Full Text] [Related]  

  • 7. E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines.
    Kitagawa M; Aonuma M; Lee SH; Fukutake S; McCormick F
    Oncogene; 2008 Sep; 27(40):5303-14. PubMed ID: 18521084
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer.
    Swetzig WM; Wang J; Das GM
    Oncotarget; 2016 Mar; 7(13):16049-69. PubMed ID: 26909605
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mdm2 inhibition of p53 induces E2F1 transactivation via p21.
    Wunderlich M; Berberich SJ
    Oncogene; 2002 Jun; 21(28):4414-21. PubMed ID: 12080472
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nutlin-3 affects expression and function of retinoblastoma protein: role of retinoblastoma protein in cellular response to nutlin-3.
    Du W; Wu J; Walsh EM; Zhang Y; Chen CY; Xiao ZX
    J Biol Chem; 2009 Sep; 284(39):26315-21. PubMed ID: 19648117
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cyclin G2 promotes cell cycle arrest in breast cancer cells responding to fulvestrant and metformin and correlates with patient survival.
    Zimmermann M; Arachchige-Don AP; Donaldson MS; Patriarchi T; Horne MC
    Cell Cycle; 2016 Dec; 15(23):3278-3295. PubMed ID: 27753529
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mouse double minute antagonist Nutlin-3a enhances chemotherapy-induced apoptosis in cancer cells with mutant p53 by activating E2F1.
    Ambrosini G; Sambol EB; Carvajal D; Vassilev LT; Singer S; Schwartz GK
    Oncogene; 2007 May; 26(24):3473-81. PubMed ID: 17146434
    [TBL] [Abstract][Full Text] [Related]  

  • 13. E2F1 inhibits MDM2 expression in a p53-dependent manner.
    Tian X; Chen Y; Hu W; Wu M
    Cell Signal; 2011 Jan; 23(1):193-200. PubMed ID: 20837136
    [TBL] [Abstract][Full Text] [Related]  

  • 14. p53-independent activation of the hdm2-P2 promoter through multiple transcription factor response elements results in elevated hdm2 expression in estrogen receptor alpha-positive breast cancer cells.
    Phelps M; Darley M; Primrose JN; Blaydes JP
    Cancer Res; 2003 May; 63(10):2616-23. PubMed ID: 12750288
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The E2F1/Rb and p53/MDM2 pathways in DNA repair and apoptosis: understanding the crosstalk to develop novel strategies for prostate cancer radiotherapy.
    Udayakumar T; Shareef MM; Diaz DA; Ahmed MM; Pollack A
    Semin Radiat Oncol; 2010 Oct; 20(4):258-66. PubMed ID: 20832018
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The oncoprotein HBXIP promotes human breast cancer growth through down-regulating p53 via miR-18b/MDM2 and pAKT/MDM2 pathways.
    Li H; Wang Z; Jiang M; Fang RP; Shi H; Shen Y; Cai XL; Liu Q; Ye K; Fan SJ; Zhang WY; Ye LH
    Acta Pharmacol Sin; 2018 Nov; 39(11):1787-1796. PubMed ID: 30181579
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The oncoprotein HBXIP modulates the feedback loop of MDM2/p53 to enhance the growth of breast cancer.
    Li H; Liu Q; Wang Z; Fang R; Shen Y; Cai X; Gao Y; Li Y; Zhang X; Ye L
    J Biol Chem; 2015 Sep; 290(37):22649-61. PubMed ID: 26229107
    [TBL] [Abstract][Full Text] [Related]  

  • 18. An inhibitory effect on cell proliferation by blockage of the MAPK/estrogen receptor/MDM2 signal pathway in gynecologic cancer.
    Suga S; Kato K; Ohgami T; Yamayoshi A; Adachi S; Asanoma K; Yamaguchi S; Arima T; Kinoshita K; Wake N
    Gynecol Oncol; 2007 May; 105(2):341-50. PubMed ID: 17306348
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential regulation of estrogen receptor alpha turnover and transactivation by Mdm2 and stress-inducing agents.
    Duong V; Boulle N; Daujat S; Chauvet J; Bonnet S; Neel H; Cavaillès V
    Cancer Res; 2007 Jun; 67(11):5513-21. PubMed ID: 17545634
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stabilization of E2F1 protein by MDM2 through the E2F1 ubiquitination pathway.
    Zhang Z; Wang H; Li M; Rayburn ER; Agrawal S; Zhang R
    Oncogene; 2005 Nov; 24(48):7238-47. PubMed ID: 16170383
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.