These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 28619760)

  • 1.
    Tong J; Tan S; Nikolovska-Coleska Z; Yu J; Zou F; Zhang L
    Mol Cancer Ther; 2017 Sep; 16(9):1979-1988. PubMed ID: 28619760
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.
    Tong J; Tan S; Zou F; Yu J; Zhang L
    Oncogene; 2017 Feb; 36(6):787-796. PubMed ID: 27399335
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Trametinib potentiates TRAIL-induced apoptosis via FBW7-dependent Mcl-1 degradation in colorectal cancer cells.
    Lin L; Ding D; Xiao X; Li B; Cao P; Li S
    J Cell Mol Med; 2020 Jun; 24(12):6822-6832. PubMed ID: 32352219
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mcl-1 Degradation Is Required for Targeted Therapeutics to Eradicate Colon Cancer Cells.
    Tong J; Wang P; Tan S; Chen D; Nikolovska-Coleska Z; Zou F; Yu J; Zhang L
    Cancer Res; 2017 May; 77(9):2512-2521. PubMed ID: 28202514
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Deguelin suppresses non-small cell lung cancer by inhibiting EGFR signaling and promoting GSK3β/FBW7-mediated Mcl-1 destabilization.
    Gao F; Yu X; Li M; Zhou L; Liu W; Li W; Liu H
    Cell Death Dis; 2020 Feb; 11(2):143. PubMed ID: 32081857
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mcl-1 inhibition overcomes intrinsic and acquired regorafenib resistance in colorectal cancer.
    Song X; Shen L; Tong J; Kuang C; Zeng S; Schoen RE; Yu J; Pei H; Zhang L
    Theranostics; 2020; 10(18):8098-8110. PubMed ID: 32724460
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation.
    Wang J; Jo U; Joo SY; Kim H
    Oncotarget; 2016 Jun; 7(24):35724-35740. PubMed ID: 27232758
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
    J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12.
    Khan OM; Almagro J; Nelson JK; Horswell S; Encheva V; Keyan KS; Clurman BE; Snijders AP; Behrens A
    Nat Commun; 2021 Apr; 12(1):2043. PubMed ID: 33824312
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting FBW7 as a Strategy to Overcome Resistance to Targeted Therapy in Non-Small Cell Lung Cancer.
    Ye M; Zhang Y; Zhang X; Zhang J; Jing P; Cao L; Li N; Li X; Yao L; Zhang J; Zhang J
    Cancer Res; 2017 Jul; 77(13):3527-3539. PubMed ID: 28522751
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mcl-1 Phosphorylation without Degradation Mediates Sensitivity to HDAC Inhibitors by Liberating BH3-Only Proteins.
    Tong J; Zheng X; Tan X; Fletcher R; Nikolovska-Coleska Z; Yu J; Zhang L
    Cancer Res; 2018 Aug; 78(16):4704-4715. PubMed ID: 29895675
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3).
    Kannan MB; Dodard-Friedman I; Blank V
    J Biol Chem; 2015 Oct; 290(43):26292-302. PubMed ID: 26306035
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The stress protein BAG3 stabilizes Mcl-1 protein and promotes survival of cancer cells and resistance to antagonist ABT-737.
    Boiani M; Daniel C; Liu X; Hogarty MD; Marnett LJ
    J Biol Chem; 2013 Mar; 288(10):6980-90. PubMed ID: 23341456
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen dysregulates expression of MCL-1 by targeting FBW7.
    Kim YJ; Kim Y; Kumar A; Kim CW; Toth Z; Cho NH; Lee HR
    PLoS Pathog; 2021 Jan; 17(1):e1009179. PubMed ID: 33471866
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of FBXW7-mediated degradation of BRAF elicits resistance to BET inhibitors in adult T cell leukemia cells.
    Yeh CH; Bellon M; Wang F; Zhang H; Fu L; Nicot C
    Mol Cancer; 2020 Sep; 19(1):139. PubMed ID: 32907612
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Zinc finger protein 746 promotes colorectal cancer progression via c-Myc stability mediated by glycogen synthase kinase 3β and F-box and WD repeat domain-containing 7.
    Jung JH; Jung DB; Kim H; Lee H; Kang SE; Srivastava SK; Yun M; Kim SH
    Oncogene; 2018 Jul; 37(27):3715-3728. PubMed ID: 29628506
    [TBL] [Abstract][Full Text] [Related]  

  • 17. E3 ubiquitin ligase Fbw7 negatively regulates granulocytic differentiation by targeting G-CSFR for degradation.
    Lochab S; Pal P; Kapoor I; Kanaujiya JK; Sanyal S; Behre G; Trivedi AK
    Biochim Biophys Acta; 2013 Dec; 1833(12):2639-2652. PubMed ID: 23820376
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ubiquitin Ligase, Fbw7, Targets CDX2 for Degradation via Two Phosphodegron Motifs in a GSK3β-Dependent Manner.
    Kumar Y; Shukla N; Thacker G; Kapoor I; Lochab S; Bhatt ML; Chattopadhyay N; Sanyal S; Trivedi AK
    Mol Cancer Res; 2016 Nov; 14(11):1097-1109. PubMed ID: 27470268
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
    Wertz IE; Kusam S; Lam C; Okamoto T; Sandoval W; Anderson DJ; Helgason E; Ernst JA; Eby M; Liu J; Belmont LD; Kaminker JS; O'Rourke KM; Pujara K; Kohli PB; Johnson AR; Chiu ML; Lill JR; Jackson PK; Fairbrother WJ; Seshagiri S; Ludlam MJ; Leong KG; Dueber EC; Maecker H; Huang DC; Dixit VM
    Nature; 2011 Mar; 471(7336):110-4. PubMed ID: 21368834
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Atypical APC/C-dependent degradation of Mcl-1 provides an apoptotic timer during mitotic arrest.
    Allan LA; Skowyra A; Rogers KI; Zeller D; Clarke PR
    EMBO J; 2018 Sep; 37(17):. PubMed ID: 29987118
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.