183 related articles for article (PubMed ID: 28621229)
1. The role of Nrf2-Keap1 axis in colorectal cancer, progression, and chemoresistance.
Sadeghi MR; Jeddi F; Soozangar N; Somi MH; Samadi N
Tumour Biol; 2017 Jun; 39(6):1010428317705510. PubMed ID: 28621229
[TBL] [Abstract][Full Text] [Related]
2. Immunohistochemical study of the Nrf2 pathway in colorectal cancer: Nrf2 expression is closely correlated to Keap1 in the tumor and Bach1 in the normal tissue.
Chang LC; Fan CW; Tseng WK; Chen JR; Chein HP; Hwang CC; Hua CC
Appl Immunohistochem Mol Morphol; 2013 Dec; 21(6):511-7. PubMed ID: 23455180
[TBL] [Abstract][Full Text] [Related]
3. Overexpression of miR-200a protects cardiomyocytes against hypoxia-induced apoptosis by modulating the kelch-like ECH-associated protein 1-nuclear factor erythroid 2-related factor 2 signaling axis.
Sun X; Zuo H; Liu C; Yang Y
Int J Mol Med; 2016 Oct; 38(4):1303-11. PubMed ID: 27573160
[TBL] [Abstract][Full Text] [Related]
4. Upregulation of nuclear factor (erythroid-derived 2)-like 2 protein level in the human colorectal adenocarcinoma cell line DLD-1 by a heterocyclic organobismuth(III) compound: Effect of organobismuth(III) compound on NRF2 signaling.
Iuchi K; Tasaki Y; Shirai S; Hisatomi H
Biomed Pharmacother; 2020 May; 125():109928. PubMed ID: 32004978
[TBL] [Abstract][Full Text] [Related]
5. Gene-expression signature regulated by the KEAP1-NRF2-CUL3 axis is associated with a poor prognosis in head and neck squamous cell cancer.
Namani A; Matiur Rahaman M; Chen M; Tang X
BMC Cancer; 2018 Jan; 18(1):46. PubMed ID: 29306329
[TBL] [Abstract][Full Text] [Related]
6. Epigenetic modifications but not genetic polymorphisms regulate KEAP1 expression in colorectal cancer.
Gao L; Yuan F; Che G; Xiao X; Nie X; Wang Y; Jia J; Kong AN; Zhang L
J Cell Biochem; 2019 Aug; 120(8):12311-12320. PubMed ID: 30825237
[TBL] [Abstract][Full Text] [Related]
7. Role of the Keap1-Nrf2 pathway in cancer.
Leinonen HM; Kansanen E; Pölönen P; Heinäniemi M; Levonen AL
Adv Cancer Res; 2014; 122():281-320. PubMed ID: 24974185
[TBL] [Abstract][Full Text] [Related]
8. Molecular mechanisms for the regulation of Nrf2-mediated cell proliferation in non-small-cell lung cancers.
Yamadori T; Ishii Y; Homma S; Morishima Y; Kurishima K; Itoh K; Yamamoto M; Minami Y; Noguchi M; Hizawa N
Oncogene; 2012 Nov; 31(45):4768-77. PubMed ID: 22249257
[TBL] [Abstract][Full Text] [Related]
9. FoxO3 reverses 5-fluorouracil resistance in human colorectal cancer cells by inhibiting the Nrf2/TR1 signaling pathway.
Liu C; Zhao Y; Wang J; Yang Y; Zhang Y; Qu X; Peng S; Yao Z; Zhao S; He B; Mi Q; Zhu Y; Liu X; Zou J; Zhang X; Du Q
Cancer Lett; 2020 Feb; 470():29-42. PubMed ID: 31811910
[TBL] [Abstract][Full Text] [Related]
10. Andrographolide protects chondrocytes from oxidative stress injury by activation of the Keap1-Nrf2-Are signaling pathway.
Li B; Jiang T; Liu H; Miao Z; Fang D; Zheng L; Zhao J
J Cell Physiol; 2018 Jan; 234(1):561-571. PubMed ID: 30071128
[TBL] [Abstract][Full Text] [Related]
11. Contradictory roles of Nrf2/Keap1 signaling pathway in cancer prevention/promotion and chemoresistance.
Jeddi F; Soozangar N; Sadeghi MR; Somi MH; Samadi N
DNA Repair (Amst); 2017 Jun; 54():13-21. PubMed ID: 28415030
[TBL] [Abstract][Full Text] [Related]
12. Nrf2/P-glycoprotein axis is associated with clinicopathological characteristics in colorectal cancer.
Sadeghi MR; Jeddi F; Soozangar N; Somi MH; Shirmohamadi M; Khaze V; Samadi N
Biomed Pharmacother; 2018 Aug; 104():458-464. PubMed ID: 29793178
[TBL] [Abstract][Full Text] [Related]
13. Dysregulation of the Keap1-Nrf2 pathway in cancer.
Leinonen HM; Kansanen E; Pölönen P; Heinäniemi M; Levonen AL
Biochem Soc Trans; 2015 Aug; 43(4):645-9. PubMed ID: 26551706
[TBL] [Abstract][Full Text] [Related]
14. Increased nuclear factor-erythroid 2 p45-related factor 2 activity protects SH-SY5Y cells against oxidative damage.
Cao TT; Ma L; Kandpal G; Warren L; Hess JF; Seabrook GR
J Neurochem; 2005 Oct; 95(2):406-17. PubMed ID: 16092930
[TBL] [Abstract][Full Text] [Related]
15. An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy.
Zhu J; Wang H; Chen F; Fu J; Xu Y; Hou Y; Kou HH; Zhai C; Nelson MB; Zhang Q; Andersen ME; Pi J
Free Radic Biol Med; 2016 Oct; 99():544-556. PubMed ID: 27634172
[TBL] [Abstract][Full Text] [Related]
16. Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405.
Probst BL; McCauley L; Trevino I; Wigley WC; Ferguson DA
PLoS One; 2015; 10(8):e0135257. PubMed ID: 26301506
[TBL] [Abstract][Full Text] [Related]
17. Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway.
Leone A; Roca MS; Ciardiello C; Terranova-Barberio M; Vitagliano C; Ciliberto G; Mancini R; Di Gennaro E; Bruzzese F; Budillon A
Free Radic Biol Med; 2015 Dec; 89():287-99. PubMed ID: 26409771
[TBL] [Abstract][Full Text] [Related]
18. RNAi-mediated silencing of nuclear factor erythroid-2-related factor 2 gene expression in non-small cell lung cancer inhibits tumor growth and increases efficacy of chemotherapy.
Singh A; Boldin-Adamsky S; Thimmulappa RK; Rath SK; Ashush H; Coulter J; Blackford A; Goodman SN; Bunz F; Watson WH; Gabrielson E; Feinstein E; Biswal S
Cancer Res; 2008 Oct; 68(19):7975-84. PubMed ID: 18829555
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of the NRF2/KEAP1 Axis: A Promising Therapeutic Strategy to Alter Redox Balance of Cancer Cells.
Panieri E; Saso L
Antioxid Redox Signal; 2021 Jun; 34(18):1428-1483. PubMed ID: 33403898
[No Abstract] [Full Text] [Related]
20. Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells.
Yang SP; Yang XZ; Cao GP
Mol Med Rep; 2015 Jul; 12(1):1145-50. PubMed ID: 25776802
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
