BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 28622392)

  • 1. Therapeutic efficacy of AAV8-mediated intrastriatal delivery of human cerebral dopamine neurotrophic factor in 6-OHDA-induced parkinsonian rat models with different disease progression.
    Wang L; Wang Z; Zhu R; Bi J; Feng X; Liu W; Wu J; Zhang H; Wu H; Kong W; Yu B; Yu X
    PLoS One; 2017; 12(6):e0179476. PubMed ID: 28622392
    [TBL] [Abstract][Full Text] [Related]  

  • 2. AAV2-mediated striatum delivery of human CDNF prevents the deterioration of midbrain dopamine neurons in a 6-hydroxydopamine induced parkinsonian rat model.
    Ren X; Zhang T; Gong X; Hu G; Ding W; Wang X
    Exp Neurol; 2013 Oct; 248():148-56. PubMed ID: 23764500
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease.
    Shen Y; Muramatsu SI; Ikeguchi K; Fujimoto KI; Fan DS; Ogawa M; Mizukami H; Urabe M; Kume A; Nagatsu I; Urano F; Suzuki T; Ichinose H; Nagatsu T; Monahan J; Nakano I; Ozawa K
    Hum Gene Ther; 2000 Jul; 11(11):1509-19. PubMed ID: 10945765
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Behavioral recovery in 6-hydroxydopamine-lesioned rats by cotransduction of striatum with tyrosine hydroxylase and aromatic L-amino acid decarboxylase genes using two separate adeno-associated virus vectors.
    Fan DS; Ogawa M; Fujimoto KI; Ikeguchi K; Ogasawara Y; Urabe M; Nishizawa M; Nakano I; Yoshida M; Nagatsu I; Ichinose H; Nagatsu T; Kurtzman GJ; Ozawa K
    Hum Gene Ther; 1998 Nov; 9(17):2527-35. PubMed ID: 9853519
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Evidence for an Additive Neurorestorative Effect of Simultaneously Administered CDNF and GDNF in Hemiparkinsonian Rats: Implications for Different Mechanism of Action.
    Voutilainen MH; De Lorenzo F; Stepanova P; Bäck S; Yu LY; Lindholm P; Pörsti E; Saarma M; Männistö PT; Tuominen RK
    eNeuro; 2017; 4(1):. PubMed ID: 28303260
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multicistronic lentiviral vector-mediated striatal gene transfer of aromatic L-amino acid decarboxylase, tyrosine hydroxylase, and GTP cyclohydrolase I induces sustained transgene expression, dopamine production, and functional improvement in a rat model of Parkinson's disease.
    Azzouz M; Martin-Rendon E; Barber RD; Mitrophanous KA; Carter EE; Rohll JB; Kingsman SM; Kingsman AJ; Mazarakis ND
    J Neurosci; 2002 Dec; 22(23):10302-12. PubMed ID: 12451130
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo.
    Lindholm P; Voutilainen MH; Laurén J; Peränen J; Leppänen VM; Andressoo JO; Lindahl M; Janhunen S; Kalkkinen N; Timmusk T; Tuominen RK; Saarma M
    Nature; 2007 Jul; 448(7149):73-7. PubMed ID: 17611540
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recombinant AAV8-mediated intrastriatal gene delivery of CDNF protects rats against methamphetamine neurotoxicity.
    Wang L; Wang Z; Xu X; Zhu R; Bi J; Liu W; Feng X; Wu H; Zhang H; Wu J; Kong W; Yu B; Yu X
    Int J Med Sci; 2017; 14(4):340-347. PubMed ID: 28553166
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reversible neurochemical changes mediated by delayed intrastriatal glial cell line-derived neurotrophic factor gene delivery in a partial Parkinson's disease rat model.
    Yang X; Mertens B; Lehtonen E; Vercammen L; Bockstael O; Chtarto A; Levivier M; Brotchi J; Michotte Y; Baekelandt V; Sarre S; Tenenbaum L
    J Gene Med; 2009 Oct; 11(10):899-912. PubMed ID: 19639608
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional effect of adeno-associated virus mediated gene transfer of aromatic L-amino acid decarboxylase into the striatum of 6-OHDA-lesioned rats.
    Sánchez-Pernaute R; Harvey-White J; Cunningham J; Bankiewicz KS
    Mol Ther; 2001 Oct; 4(4):324-30. PubMed ID: 11592835
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease.
    Huotarinen A; Penttinen AM; Bäck S; Voutilainen MH; Julku U; Piepponen TP; Männistö PT; Saarma M; Tuominen R; Laakso A; Airavaara M
    Neuroscience; 2018 Mar; 374():250-263. PubMed ID: 29408408
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of engineered conserved dopamine neurotrophic factor-expressing bone marrow stromal cells on dopaminergic neurons following 6-OHDA administrations.
    Mei J; Niu C
    Mol Med Rep; 2015 Feb; 11(2):1207-13. PubMed ID: 25373844
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Carbidopa-based modulation of the functional effect of the AAV2-hAADC gene therapy in 6-OHDA lesioned rats.
    Ciesielska A; Sharma N; Beyer J; Forsayeth J; Bankiewicz K
    PLoS One; 2015; 10(4):e0122708. PubMed ID: 25860990
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dimerizer regulation of AADC expression and behavioral response in AAV-transduced 6-OHDA lesioned rats.
    Sanftner LM; Rivera VM; Suzuki BM; Feng L; Berk L; Zhou S; Forsayeth JR; Clackson T; Cunningham J
    Mol Ther; 2006 Jan; 13(1):167-74. PubMed ID: 16126007
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease.
    Voutilainen MH; Bäck S; Peränen J; Lindholm P; Raasmaja A; Männistö PT; Saarma M; Tuominen RK
    Exp Neurol; 2011 Mar; 228(1):99-108. PubMed ID: 21185834
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Correction of a rat model of Parkinson's disease by coexpression of tyrosine hydroxylase and aromatic amino acid decarboxylase from a helper virus-free herpes simplex virus type 1 vector.
    Sun M; Zhang GR; Kong L; Holmes C; Wang X; Zhang W; Goldstein DS; Geller AI
    Hum Gene Ther; 2003 Mar; 14(5):415-24. PubMed ID: 12691607
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhanced efficacy of the CDNF/MANF family by combined intranigral overexpression in the 6-OHDA rat model of Parkinson's disease.
    Cordero-Llana Ó; Houghton BC; Rinaldi F; Taylor H; Yáñez-Muñoz RJ; Uney JB; Wong LF; Caldwell MA
    Mol Ther; 2015 Feb; 23(2):244-54. PubMed ID: 25369767
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approach.
    Bankiewicz KS; Eberling JL; Kohutnicka M; Jagust W; Pivirotto P; Bringas J; Cunningham J; Budinger TF; Harvey-White J
    Exp Neurol; 2000 Jul; 164(1):2-14. PubMed ID: 10877910
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes.
    Muramatsu S; Fujimoto K; Ikeguchi K; Shizuma N; Kawasaki K; Ono F; Shen Y; Wang L; Mizukami H; Kume A; Matsumura M; Nagatsu I; Urano F; Ichinose H; Nagatsu T; Terao K; Nakano I; Ozawa K
    Hum Gene Ther; 2002 Feb; 13(3):345-54. PubMed ID: 11860702
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Transient transfection of human CDNF gene reduces the 6-hydroxydopamine-induced neuroinflammation in the rat substantia nigra.
    Nadella R; Voutilainen MH; Saarma M; Gonzalez-Barrios JA; Leon-Chavez BA; Jiménez JM; Jiménez SH; Escobedo L; Martinez-Fong D
    J Neuroinflammation; 2014 Dec; 11():209. PubMed ID: 25511018
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.