BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 28623230)

  • 21. Membrane-mediated induction and sorting of K-Ras microdomain signaling platforms.
    Weise K; Kapoor S; Denter C; Nikolaus J; Opitz N; Koch S; Triola G; Herrmann A; Waldmann H; Winter R
    J Am Chem Soc; 2011 Feb; 133(4):880-7. PubMed ID: 21141956
    [TBL] [Abstract][Full Text] [Related]  

  • 22. KRAS Prenylation Is Required for Bivalent Binding with Calmodulin in a Nucleotide-Independent Manner.
    Agamasu C; Ghirlando R; Taylor T; Messing S; Tran TH; Bindu L; Tonelli M; Nissley DV; McCormick F; Stephen AG
    Biophys J; 2019 Mar; 116(6):1049-1063. PubMed ID: 30846362
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Is Nanoclustering essential for all oncogenic KRas pathways? Can it explain why wild-type KRas can inhibit its oncogenic variant?
    Nussinov R; Tsai CJ; Jang H
    Semin Cancer Biol; 2019 Feb; 54():114-120. PubMed ID: 29307569
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Comparison of the Conformations of KRAS Isoforms, K-Ras4A and K-Ras4B, Points to Similarities and Significant Differences.
    Chakrabarti M; Jang H; Nussinov R
    J Phys Chem B; 2016 Feb; 120(4):667-79. PubMed ID: 26761128
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Calmodulin extracts the Ras family protein RalA from lipid bilayers by engagement with two membrane-targeting motifs.
    Chamberlain SG; Gohlke A; Shafiq A; Squires IJ; Owen D; Mott HR
    Proc Natl Acad Sci U S A; 2021 Sep; 118(36):. PubMed ID: 34480001
    [TBL] [Abstract][Full Text] [Related]  

  • 26. K-Ras4B phosphorylation at Ser181 is inhibited by calmodulin and modulates K-Ras activity and function.
    Alvarez-Moya B; López-Alcalá C; Drosten M; Bachs O; Agell N
    Oncogene; 2010 Nov; 29(44):5911-22. PubMed ID: 20802526
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Markov State Models and Molecular Dynamics Simulations Reveal the Conformational Transition of the Intrinsically Disordered Hypervariable Region of K-Ras4B to the Ordered Conformation.
    Zhang H; Ni D; Fan J; Li M; Zhang J; Hua C; Nussinov R; Lu S
    J Chem Inf Model; 2022 Sep; 62(17):4222-4231. PubMed ID: 35994329
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Facile Synthesis of Boc-Protected Selenocystine and its Compatibility with Late-Stage Farnesylation at Cysteine Site.
    Zhu PC; Chen YX
    Protein Pept Lett; 2021; 28(6):603-611. PubMed ID: 33357178
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The disordered hypervariable region and the folded catalytic domain of oncogenic K-Ras4B partner in phospholipid binding.
    Banerjee A; Jang H; Nussinov R; Gaponenko V
    Curr Opin Struct Biol; 2016 Feb; 36():10-7. PubMed ID: 26709496
    [TBL] [Abstract][Full Text] [Related]  

  • 30. PDEδ Binding to Ras Isoforms Provides a Route to Proper Membrane Localization.
    Muratcioglu S; Jang H; Gursoy A; Keskin O; Nussinov R
    J Phys Chem B; 2017 Jun; 121(24):5917-5927. PubMed ID: 28540724
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Dissociation of the Signaling Protein K-Ras4B from Lipid Membranes Induced by a Molecular Tweezer.
    Li L; Erwin N; Möbitz S; Niemeyer F; Schrader T; Winter RHA
    Chemistry; 2019 Jul; 25(42):9827-9833. PubMed ID: 31141233
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A high pressure study of calmodulin-ligand interactions using small-angle X-ray and elastic incoherent neutron scattering.
    Cinar S; Al-Ayoubi S; Sternemann C; Peters J; Winter R; Czeslik C
    Phys Chem Chem Phys; 2018 Jan; 20(5):3514-3522. PubMed ID: 29336441
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Expression, purification, and characterization of soluble K-Ras4B for structural analysis.
    Abraham SJ; Muhamed I; Nolet R; Yeung F; Gaponenko V
    Protein Expr Purif; 2010 Oct; 73(2):125-31. PubMed ID: 20566322
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Phosphorylation Weakens but Does Not Inhibit Membrane Binding and Clustering of K-Ras4B.
    Zhang SY; Sperlich B; Li FY; Al-Ayoubi S; Chen HX; Zhao YF; Li YM; Weise K; Winter R; Chen YX
    ACS Chem Biol; 2017 Jun; 12(6):1703-1710. PubMed ID: 28448716
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Modeling and subtleties of K-Ras and Calmodulin interaction.
    Garrido E; Lázaro J; Jaumot M; Agell N; Rubio-Martinez J
    PLoS Comput Biol; 2018 Oct; 14(10):e1006552. PubMed ID: 30376570
    [TBL] [Abstract][Full Text] [Related]  

  • 36. High affinity for farnesyltransferase and alternative prenylation contribute individually to K-Ras4B resistance to farnesyltransferase inhibitors.
    Fiordalisi JJ; Johnson RL; Weinbaum CA; Sakabe K; Chen Z; Casey PJ; Cox AD
    J Biol Chem; 2003 Oct; 278(43):41718-27. PubMed ID: 12882980
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Application of reductive ¹³C-methylation of lysines to enhance the sensitivity of conventional NMR methods.
    Chavan TS; Abraham S; Gaponenko V
    Molecules; 2013 Jun; 18(6):7103-19. PubMed ID: 23778120
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Calmodulin (CaM) Activates PI3Kα by Targeting the "Soft" CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85α.
    Zhang M; Li Z; Wang G; Jang H; Sacks DB; Zhang J; Gaponenko V; Nussinov R
    J Phys Chem B; 2018 Dec; 122(49):11137-11146. PubMed ID: 30047727
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Dissociation of the K-Ras4B/PDEδ complex upon contact with lipid membranes: membrane delivery instead of extraction.
    Weise K; Kapoor S; Werkmüller A; Möbitz S; Zimmermann G; Triola G; Waldmann H; Winter R
    J Am Chem Soc; 2012 Jul; 134(28):11503-10. PubMed ID: 22721555
    [TBL] [Abstract][Full Text] [Related]  

  • 40. K-Ras4B lipoprotein synthesis: biochemical characterization, functional properties, and dimer formation.
    Dementiev A
    Protein Expr Purif; 2012 Jul; 84(1):86-93. PubMed ID: 22569482
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.