These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 28624703)

  • 1. Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.
    Tang Y; Rodríguez-Salarichs J; Zhao Y; Cai P; Estévez-Gallego J; Balaguer-Pérez F; Redondo Horcajo M; Lucena-Agell D; Barasoain I; Díaz JF; Fang WS
    Eur J Med Chem; 2017 Sep; 137():488-503. PubMed ID: 28624703
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A semisynthetic taxane Yg-3-46a effectively evades P-glycoprotein and β-III tubulin mediated tumor drug resistance in vitro.
    Cai P; Lu P; Sharom FJ; Fang WS
    Cancer Lett; 2013 Dec; 341(2):214-23. PubMed ID: 23941826
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances.
    Matesanz R; Trigili C; Rodríguez-Salarichs J; Zanardi I; Pera B; Nogales A; Fang WS; Jímenez-Barbero J; Canales A; Barasoain I; Ojima I; Díaz JF
    Bioorg Med Chem; 2014 Sep; 22(18):5078-90. PubMed ID: 25047938
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and Cytotoxicity of 7,9-
    Zhao Y; Wang TE; Mills A; Gago F; Fang WS
    Molecules; 2019 Jun; 24(11):. PubMed ID: 31181726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of C2-C3'N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity.
    Querolle O; Dubois J; Thoret S; Roussi F; Guéritte F; Guénard D
    J Med Chem; 2004 Nov; 47(24):5937-44. PubMed ID: 15537348
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of C7 substitutions in a high affinity microtubule-binding taxane on antitumor activity and drug transport.
    Xiao X; Wu J; Trigili C; Chen H; Chu JW; Zhao Y; Lu P; Sheng L; Li Y; Sharom FJ; Barasoain I; Diaz JF; Fang WS
    Bioorg Med Chem Lett; 2011 Aug; 21(16):4852-6. PubMed ID: 21764308
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and SAR study of Fluorine-containing 3rd-generation taxoids.
    Wang C; Chen L; Sun Y; Guo W; Taouil AK; Ojima I
    Bioorg Chem; 2022 Feb; 119():105578. PubMed ID: 34979464
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 1: Synthesis and biological activities of docetaxel analogues with a peptide side chain at C3'.
    Larroque AL; Dubois J; Thoret S; Aubert G; Guénard D; Guéritte F
    Bioorg Med Chem Lett; 2005 Nov; 15(21):4722-6. PubMed ID: 16165352
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 2: synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives.
    Larroque AL; Dubois J; Thoret S; Aubert G; Chiaroni A; Guéritte F; Guénard D
    Bioorg Med Chem; 2007 Jan; 15(1):563-74. PubMed ID: 17064914
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, synthesis, and biological evaluation of new-generation taxoids.
    Ojima I; Chen J; Sun L; Borella CP; Wang T; Miller ML; Lin S; Geng X; Kuznetsova L; Qu C; Gallager D; Zhao X; Zanardi I; Xia S; Horwitz SB; Mallen-St Clair J; Guerriero JL; Bar-Sagi D; Veith JM; Pera P; Bernacki RJ
    J Med Chem; 2008 Jun; 51(11):3203-21. PubMed ID: 18465846
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The seco-taxane IDN5390 is able to target class III beta-tubulin and to overcome paclitaxel resistance.
    Ferlini C; Raspaglio G; Mozzetti S; Cicchillitti L; Filippetti F; Gallo D; Fattorusso C; Campiani G; Scambia G
    Cancer Res; 2005 Mar; 65(6):2397-405. PubMed ID: 15781655
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design, synthesis and structure-activity relationships of novel taxane-based multidrug resistance reversal agents.
    Ojima I; Borella CP; Wu X; Bounaud PY; Oderda CF; Sturm M; Miller ML; Chakravarty S; Chen J; Huang Q; Pera P; Brooks TA; Baer MR; Bernacki RJ
    J Med Chem; 2005 Mar; 48(6):2218-28. PubMed ID: 15771464
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overcoming tumor drug resistance with high-affinity taxanes: a SAR study of C2-modified 7-acyl-10-deacetyl cephalomannines.
    Yang CG; Barasoain I; Li X; Matesanz R; Liu R; Sharom FJ; Yin DL; Díaz JF; Fang WS
    ChemMedChem; 2007 May; 2(5):691-701. PubMed ID: 17385753
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Overcoming tumor drug resistance with C2-modified 10-deacetyl-7-propionyl cephalomannines: a QSAR study.
    Hansch C; Verma RP
    Mol Pharm; 2009; 6(3):849-60. PubMed ID: 19334723
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Preclinical pharmacologic evaluation of MST-997, an orally active taxane with superior in vitro and in vivo efficacy in paclitaxel- and docetaxel-resistant tumor models.
    Sampath D; Greenberger LM; Beyer C; Hari M; Liu H; Baxter M; Yang S; Rios C; Discafani C
    Clin Cancer Res; 2006 Jun; 12(11 Pt 1):3459-69. PubMed ID: 16740771
    [TBL] [Abstract][Full Text] [Related]  

  • 16. βIII-tubulin enhances efficacy of cabazitaxel as compared with docetaxel.
    Smiyun G; Azarenko O; Miller H; Rifkind A; LaPointe NE; Wilson L; Jordan MA
    Cancer Chemother Pharmacol; 2017 Jul; 80(1):151-164. PubMed ID: 28567478
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel C-seco-taxoids possessing high potency against paclitaxel-resistant cancer cell lines overexpressing class III beta-tubulin.
    Pepe A; Sun L; Zanardi I; Wu X; Ferlini C; Fontana G; Bombardelli E; Ojima I
    Bioorg Med Chem Lett; 2009 Jun; 19(12):3300-4. PubMed ID: 19423340
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms.
    Risinger AL; Jackson EM; Polin LA; Helms GL; LeBoeuf DA; Joe PA; Hopper-Borge E; Ludueña RF; Kruh GD; Mooberry SL
    Cancer Res; 2008 Nov; 68(21):8881-8. PubMed ID: 18974132
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.
    Field JJ; Pera B; Calvo E; Canales A; Zurwerra D; Trigili C; Rodríguez-Salarichs J; Matesanz R; Kanakkanthara A; Wakefield SJ; Singh AJ; Jiménez-Barbero J; Northcote P; Miller JH; López JA; Hamel E; Barasoain I; Altmann KH; Díaz JF
    Chem Biol; 2012 Jun; 19(6):686-98. PubMed ID: 22726683
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of a lathyrane-type diterpenoid EM-E-11-4 as a novel paclitaxel resistance reversing agent with multiple mechanisms of action.
    Liu Q; Cai P; Guo S; Shi J; Sun H
    Aging (Albany NY); 2020 Feb; 12(4):3713-3729. PubMed ID: 32108588
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.