424 related articles for article (PubMed ID: 28624910)
1. Clinical pharmacology and clinical trials of ribonucleotide reductase inhibitors: is it a viable cancer therapy?
Mannargudi MB; Deb S
J Cancer Res Clin Oncol; 2017 Aug; 143(8):1499-1529. PubMed ID: 28624910
[TBL] [Abstract][Full Text] [Related]
2. Evolving role of ribonucleoside reductase inhibitors in hematologic malignancies.
Tsimberidou AM; Alvarado Y; Giles FJ
Expert Rev Anticancer Ther; 2002 Aug; 2(4):437-48. PubMed ID: 12647987
[TBL] [Abstract][Full Text] [Related]
3. Ribonucleotide reductase inhibitors and future drug design.
Shao J; Zhou B; Chu B; Yen Y
Curr Cancer Drug Targets; 2006 Aug; 6(5):409-31. PubMed ID: 16918309
[TBL] [Abstract][Full Text] [Related]
4. Interaction of gallium nitrate with other inhibitors of ribonucleotide reductase: effects on the proliferation of human leukemic cells.
Myette MS; Elford HL; Chitambar CR
Cancer Lett; 1998 Jul; 129(2):199-204. PubMed ID: 9719462
[TBL] [Abstract][Full Text] [Related]
5. Inhibitors of the Cancer Target Ribonucleotide Reductase, Past and Present.
Huff SE; Winter JM; Dealwis CG
Biomolecules; 2022 Jun; 12(6):. PubMed ID: 35740940
[TBL] [Abstract][Full Text] [Related]
6. Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity.
Finch RA; Liu M; Grill SP; Rose WC; Loomis R; Vasquez KM; Cheng Y; Sartorelli AC
Biochem Pharmacol; 2000 Apr; 59(8):983-91. PubMed ID: 10692563
[TBL] [Abstract][Full Text] [Related]
7. Targeting ribonucleotide reductase for cancer therapy.
Shao J; Liu X; Zhu L; Yen Y
Expert Opin Ther Targets; 2013 Dec; 17(12):1423-37. PubMed ID: 24083455
[TBL] [Abstract][Full Text] [Related]
8. Syntheses and antitumor activities of potent inhibitors of ribonucleotide reductase: 3-amino-4-methylpyridine-2-carboxaldehyde-thiosemicarba-zone (3-AMP), 3-amino-pyridine-2-carboxaldehyde-thiosemicarbazone (3-AP) and its water-soluble prodrugs.
Li J; Zheng LM; King I; Doyle TW; Chen SH
Curr Med Chem; 2001 Feb; 8(2):121-33. PubMed ID: 11172670
[TBL] [Abstract][Full Text] [Related]
9. GTI-2040 displays cooperative anti-tumor activity when combined with interferon alpha against human renal carcinoma xenografts.
Vassilakos A; Lee Y; Viau S; Feng N; Jin H; Chai V; Wang M; Avolio T; Wright J; Young A
Int J Oncol; 2009 Jan; 34(1):33-42. PubMed ID: 19082475
[TBL] [Abstract][Full Text] [Related]
10. Stable suppression of the R2 subunit of ribonucleotide reductase by R2-targeted short interference RNA sensitizes p53(-/-) HCT-116 colon cancer cells to DNA-damaging agents and ribonucleotide reductase inhibitors.
Lin ZP; Belcourt MF; Cory JG; Sartorelli AC
J Biol Chem; 2004 Jun; 279(26):27030-8. PubMed ID: 15096505
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of ribonucleotide reductase reduces neointimal formation following balloon injury.
Henry JC; Bonar MM; Kearns PN; Cui H; Mutchler MM; Martin MV; Orsini AR; Elford HL; Bush CA; Zweier JL; Cardounel AJ
J Pharmacol Exp Ther; 2005 Jul; 314(1):70-6. PubMed ID: 15814568
[TBL] [Abstract][Full Text] [Related]
12. GTI-2040, an antisense agent targeting the small subunit component (R2) of human ribonucleotide reductase, shows potent antitumor activity against a variety of tumors.
Lee Y; Vassilakos A; Feng N; Lam V; Xie H; Wang M; Jin H; Xiong K; Liu C; Wright J; Young A
Cancer Res; 2003 Jun; 63(11):2802-11. PubMed ID: 12782585
[TBL] [Abstract][Full Text] [Related]
13. Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir.
Bhave S; Elford H; McVoy MA
Antiviral Res; 2013 Oct; 100(1):151-8. PubMed ID: 23933116
[TBL] [Abstract][Full Text] [Related]
14. DHS (trans-4,4'-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2).
Chen CW; Li Y; Hu S; Zhou W; Meng Y; Li Z; Zhang Y; Sun J; Bo Z; DePamphilis ML; Yen Y; Han Z; Zhu W
Oncogene; 2019 Mar; 38(13):2364-2379. PubMed ID: 30518875
[TBL] [Abstract][Full Text] [Related]
15. Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance.
Månsson E; Flordal E; Liliemark J; Spasokoukotskaja T; Elford H; Lagercrantz S; Eriksson S; Albertioni F
Biochem Pharmacol; 2003 Jan; 65(2):237-47. PubMed ID: 12504799
[TBL] [Abstract][Full Text] [Related]
16. The enzyme ribonucleotide reductase: target for antitumor and anti-HIV therapy.
Szekeres T; Fritzer-Szekeres M; Elford HL
Crit Rev Clin Lab Sci; 1997; 34(6):503-28. PubMed ID: 9439883
[TBL] [Abstract][Full Text] [Related]
17. The efficacy of the ribonucleotide reductase inhibitor Didox in preclinical models of AML.
Cook GJ; Caudell DL; Elford HL; Pardee TS
PLoS One; 2014; 9(11):e112619. PubMed ID: 25402485
[TBL] [Abstract][Full Text] [Related]
18. Didox, a ribonucleotide reductase inhibitor, induces apoptosis and inhibits DNA repair in multiple myeloma cells.
Raje N; Kumar S; Hideshima T; Ishitsuka K; Yasui H; Chhetri S; Vallet S; Vonescu E; Shiraishi N; Kiziltepe T; Elford HL; Munshi NC; Anderson KC
Br J Haematol; 2006 Oct; 135(1):52-61. PubMed ID: 16925573
[TBL] [Abstract][Full Text] [Related]
19. Phase I and pharmacokinetic study of triapine, a potent ribonucleotide reductase inhibitor, administered daily for five days in patients with advanced solid tumors.
Murren J; Modiano M; Clairmont C; Lambert P; Savaraj N; Doyle T; Sznol M
Clin Cancer Res; 2003 Sep; 9(11):4092-100. PubMed ID: 14519631
[TBL] [Abstract][Full Text] [Related]
20. Regulation and drug resistance mechanisms of mammalian ribonucleotide reductase, and the significance to DNA synthesis.
Wright JA; Chan AK; Choy BK; Hurta RA; McClarty GA; Tagger AY
Biochem Cell Biol; 1990 Dec; 68(12):1364-71. PubMed ID: 2085432
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
