These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 28625788)

  • 1. Structural and Functional Trends in Dehydrating Bimodules from trans-Acyltransferase Polyketide Synthases.
    Wagner DT; Zeng J; Bailey CB; Gay DC; Yuan F; Manion HR; Keatinge-Clay AT
    Structure; 2017 Jul; 25(7):1045-1055.e2. PubMed ID: 28625788
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural and functional studies of a trans-acyltransferase polyketide assembly line enzyme that catalyzes stereoselective α- and β-ketoreduction.
    Piasecki SK; Zheng J; Axelrod AJ; Detelich ME; Keatinge-Clay AT
    Proteins; 2014 Sep; 82(9):2067-77. PubMed ID: 24634061
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Mechanism of Dehydrating Bimodules in trans-Acyltransferase Polyketide Biosynthesis: A Showcase Study on Hepatoprotective Hangtaimycin.
    Luo M; Xu H; Dong Y; Shen K; Lu J; Yin Z; Qi M; Sun G; Tang L; Xiang J; Deng Z; Dickschat JS; Sun Y
    Angew Chem Int Ed Engl; 2021 Aug; 60(35):19139-19143. PubMed ID: 34219345
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase.
    Castonguay R; Valenzano CR; Chen AY; Keatinge-Clay A; Khosla C; Cane DE
    J Am Chem Soc; 2008 Sep; 130(35):11598-9. PubMed ID: 18693734
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A double-hotdog with a new trick: structure and mechanism of the trans-acyltransferase polyketide synthase enoyl-isomerase.
    Gay DC; Spear PJ; Keatinge-Clay AT
    ACS Chem Biol; 2014 Oct; 9(10):2374-81. PubMed ID: 25089587
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural rearrangements of a polyketide synthase module during its catalytic cycle.
    Whicher JR; Dutta S; Hansen DA; Hale WA; Chemler JA; Dosey AM; Narayan AR; Håkansson K; Sherman DH; Smith JL; Skiniotis G
    Nature; 2014 Jun; 510(7506):560-4. PubMed ID: 24965656
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Elucidation of the Stereospecificity of C-Methyltransferases from trans-AT Polyketide Synthases.
    Xie X; Khosla C; Cane DE
    J Am Chem Soc; 2017 May; 139(17):6102-6105. PubMed ID: 28430424
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural and Functional Studies of a Pyran Synthase Domain from a trans-Acyltransferase Assembly Line.
    Wagner DT; Zhang Z; Meoded RA; Cepeda AJ; Piel J; Keatinge-Clay AT
    ACS Chem Biol; 2018 Apr; 13(4):975-983. PubMed ID: 29481043
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional and Structural Analyses of the Split-Dehydratase Domain in the Biosynthesis of Macrolactam Polyketide Cremimycin.
    Kawasaki D; Miyanaga A; Chisuga T; Kudo F; Eguchi T
    Biochemistry; 2019 Dec; 58(48):4799-4803. PubMed ID: 31721563
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The final steps of bacillaene biosynthesis in Bacillus amyloliquefaciens FZB42: direct evidence for beta,gamma dehydration by a trans-acyltransferase polyketide synthase.
    Moldenhauer J; Götz DC; Albert CR; Bischof SK; Schneider K; Süssmuth RD; Engeser M; Gross H; Bringmann G; Piel J
    Angew Chem Int Ed Engl; 2010 Feb; 49(8):1465-7. PubMed ID: 20087918
    [No Abstract]   [Full Text] [Related]  

  • 11. Structural and functional analysis of C2-type ketoreductases from modular polyketide synthases.
    Zheng J; Keatinge-Clay AT
    J Mol Biol; 2011 Jul; 410(1):105-17. PubMed ID: 21570406
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Portability and Structure of the Four-Helix Bundle Docking Domains of trans-Acyltransferase Modular Polyketide Synthases.
    Zeng J; Wagner DT; Zhang Z; Moretto L; Addison JD; Keatinge-Clay AT
    ACS Chem Biol; 2016 Sep; 11(9):2466-74. PubMed ID: 27362945
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases.
    Keatinge-Clay AT; Stroud RM
    Structure; 2006 Apr; 14(4):737-48. PubMed ID: 16564177
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modeling holo-ACP:DH and holo-ACP:KR complexes of modular polyketide synthases: a docking and molecular dynamics study.
    Anand S; Mohanty D
    BMC Struct Biol; 2012 May; 12():10. PubMed ID: 22639887
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
    Dunn BJ; Watts KR; Robbins T; Cane DE; Khosla C
    Biochemistry; 2014 Jun; 53(23):3796-806. PubMed ID: 24871074
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Autonomous folding of interdomain regions of a modular polyketide synthase.
    Richter CD; Stanmore DA; Miguel RN; Moncrieffe MC; Tran L; Brewerton S; Meersman F; Broadhurst RW; Weissman KJ
    FEBS J; 2007 May; 274(9):2196-209. PubMed ID: 17419733
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A close look at a ketosynthase from a trans-acyltransferase modular polyketide synthase.
    Gay DC; Gay G; Axelrod AJ; Jenner M; Kohlhaas C; Kampa A; Oldham NJ; Piel J; Keatinge-Clay AT
    Structure; 2014 Mar; 22(3):444-51. PubMed ID: 24508341
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural studies of an A2-type modular polyketide synthase ketoreductase reveal features controlling α-substituent stereochemistry.
    Zheng J; Piasecki SK; Keatinge-Clay AT
    ACS Chem Biol; 2013 Sep; 8(9):1964-71. PubMed ID: 23755878
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural and Functional Studies of a gem-Dimethylating Methyltransferase from a trans-Acyltransferase Assembly Line.
    Meinke JL; Mehaffey MR; Wagner DT; Sun N; Zhang Z; Brodbelt JS; Keatinge-Clay AT
    ACS Chem Biol; 2018 Dec; 13(12):3306-3314. PubMed ID: 30371052
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insights into modular polyketide synthase loops aided by repetitive sequences.
    Hirsch M; Kumru K; Desai RR; Fitzgerald BJ; Miyazawa T; Ray KA; Saif N; Spears S; Keatinge-Clay AT
    Proteins; 2021 Sep; 89(9):1099-1110. PubMed ID: 33843112
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.