BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

294 related articles for article (PubMed ID: 2863141)

  • 1. Thrombin specificity. Requirement for apolar amino acids adjacent to the thrombin cleavage site of polypeptide substrate.
    Chang JY
    Eur J Biochem; 1985 Sep; 151(2):217-24. PubMed ID: 2863141
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of the P2' and P3' specificities of thrombin using fluorescence-quenched substrates and mapping of the subsites by mutagenesis.
    Le Bonniec BF; Myles T; Johnson T; Knight CG; Tapparelli C; Stone SR
    Biochemistry; 1996 Jun; 35(22):7114-22. PubMed ID: 8679538
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vitro cleavage of internally quenched fluorogenic human proparathyroid hormone and proparathyroid-related peptide substrates by furin. Generation of a potent inhibitor.
    Lazure C; Gauthier D; Jean F; Boudreault A; Seidah NG; Bennett HP; Hendy GN
    J Biol Chem; 1998 Apr; 273(15):8572-80. PubMed ID: 9535830
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substrate specificity of porcine renin: P1', P1, and P3 residues of renin substrates are crucial for activity.
    Wang W; Liang TC
    Biochemistry; 1994 Dec; 33(48):14636-41. PubMed ID: 7981226
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Substrate specificity of the Escherichia coli outer membrane protease OmpT.
    McCarter JD; Stephens D; Shoemaker K; Rosenberg S; Kirsch JF; Georgiou G
    J Bacteriol; 2004 Sep; 186(17):5919-25. PubMed ID: 15317797
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Propeptide processing during factor IX biosynthesis. Effect of point mutations adjacent to the propeptide cleavage site.
    Bristol JA; Furie BC; Furie B
    J Biol Chem; 1993 Apr; 268(10):7577-84. PubMed ID: 8463288
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Determination of the P1', P2' and P3' subsite-specificity of factor Xa.
    Ludeman JP; Pike RN; Bromfield KM; Duggan PJ; Cianci J; Le Bonniec B; Whisstock JC; Bottomley SP
    Int J Biochem Cell Biol; 2003 Feb; 35(2):221-5. PubMed ID: 12479872
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HIV-1 Protease Uses Bi-Specific S2/S2' Subsites to Optimize Cleavage of Two Classes of Target Sites.
    Potempa M; Lee SK; Kurt Yilmaz N; Nalivaika EA; Rogers A; Spielvogel E; Carter CW; Schiffer CA; Swanstrom R
    J Mol Biol; 2018 Dec; 430(24):5182-5195. PubMed ID: 30414407
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The extended cleavage specificity of human thrombin.
    Gallwitz M; Enoksson M; Thorpe M; Hellman L
    PLoS One; 2012; 7(2):e31756. PubMed ID: 22384068
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinetic and modeling studies of S3-S3' subsites of HIV proteinases.
    Tözsér J; Weber IT; Gustchina A; Bláha I; Copeland TD; Louis JM; Oroszlan S
    Biochemistry; 1992 May; 31(20):4793-800. PubMed ID: 1591240
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Active-site specificity of digestive aspartic peptidases from the four species of Plasmodium that infect humans using chromogenic combinatorial peptide libraries.
    Beyer BB; Johnson JV; Chung AY; Li T; Madabushi A; Agbandje-McKenna M; McKenna R; Dame JB; Dunn BM
    Biochemistry; 2005 Feb; 44(6):1768-79. PubMed ID: 15697202
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mapping the active sites of bovine thrombin, factor IXa, factor Xa, factor XIa, factor XIIa, plasma kallikrein, and trypsin with amino acid and peptide thioesters: development of new sensitive substrates.
    McRae BJ; Kurachi K; Heimark RL; Fujikawa K; Davie EW; Powers JC
    Biochemistry; 1981 Dec; 20(25):7196-206. PubMed ID: 6976185
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Specificity of the wound-induced leucine aminopeptidase (LAP-A) of tomato activity on dipeptide and tripeptide substrates.
    Gu YQ; Walling LL
    Eur J Biochem; 2000 Feb; 267(4):1178-87. PubMed ID: 10672029
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.
    Slon-Usakiewicz JJ; Sivaraman J; Li Y; Cygler M; Konishi Y
    Biochemistry; 2000 Mar; 39(9):2384-91. PubMed ID: 10694407
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rational design and selection of bivalent peptide ligands of thrombin incorporating P4-P1 tetrapeptide sequences: from good substrates to potent inhibitors.
    Su Z; Vinogradova A; Koutychenko A; Tolkatchev D; Ni F
    Protein Eng Des Sel; 2004 Aug; 17(8):647-57. PubMed ID: 15358856
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Substrate specificity and novel selective inhibitors of TNF-alpha converting enzyme (TACE) from two-dimensional substrate mapping.
    Lambert MH; Blackburn RK; Seaton TD; Kassel DB; Kinder DS; Leesnitzer MA; Bickett DM; Warner JR; Andersen MW; Badiang JG; Cowan DJ; Gaul MD; Petrov KG; Rabinowitz MH; Wiethe RW; Becherer JD; McDougald DL; Musso DL; Andrews RC; Moss ML
    Comb Chem High Throughput Screen; 2005 Jun; 8(4):327-39. PubMed ID: 16101009
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, and evaluation of matrix metalloprotease inhibitors bearing cyclopropane-derived peptidomimetics as P1' and P2' replacements.
    Reichelt A; Gaul C; Frey RR; Kennedy A; Martin SF
    J Org Chem; 2002 Jun; 67(12):4062-75. PubMed ID: 12054939
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cleavage specificity of the subtilisin-like protease C1 from soybean.
    Boyd PM; Barnaby N; Tan-Wilson A; Wilson KA
    Biochim Biophys Acta; 2002 Apr; 1596(2):269-82. PubMed ID: 12007608
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Switching the substrate specificity of the two-component NS2B-NS3 flavivirus proteinase by structure-based mutagenesis.
    Shiryaev SA; Ratnikov BI; Aleshin AE; Kozlov IA; Nelson NA; Lebl M; Smith JW; Liddington RC; Strongin AY
    J Virol; 2007 May; 81(9):4501-9. PubMed ID: 17301157
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Specificity of the dynorphin-processing endoprotease: comparison with prohormone convertases.
    Berman Y; Juliano L; Devi LA
    J Neurochem; 1999 May; 72(5):2120-6. PubMed ID: 10217293
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.