179 related articles for article (PubMed ID: 28632395)
21. Screening of new huprines--inhibitors of acetylcholinesterases by electrospray ionization ion trap mass spectrometry.
Ziemianin A; Ronco C; Dolé R; Jean L; Renard PY; Lange CM
J Pharm Biomed Anal; 2012 Nov; 70():1-5. PubMed ID: 22677656
[TBL] [Abstract][Full Text] [Related]
22. A novel class of multitarget anti-Alzheimer benzohomoadamantane‒chlorotacrine hybrids modulating cholinesterases and glutamate NMDA receptors.
Pérez-Areales FJ; Turcu AL; Barniol-Xicota M; Pont C; Pivetta D; Espargaró A; Bartolini M; De Simone A; Andrisano V; Pérez B; Sabate R; Sureda FX; Vázquez S; Muñoz-Torrero D
Eur J Med Chem; 2019 Oct; 180():613-626. PubMed ID: 31351393
[TBL] [Abstract][Full Text] [Related]
23. Benzylpiperidine-Linked Diarylthiazoles as Potential Anti-Alzheimer's Agents: Synthesis and Biological Evaluation.
Shidore M; Machhi J; Shingala K; Murumkar P; Sharma MK; Agrawal N; Tripathi A; Parikh Z; Pillai P; Yadav MR
J Med Chem; 2016 Jun; 59(12):5823-46. PubMed ID: 27253679
[TBL] [Abstract][Full Text] [Related]
24. Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl- and butyryl-cholinesterase.
Nachon F; Carletti E; Ronco C; Trovaslet M; Nicolet Y; Jean L; Renard PY
Biochem J; 2013 Aug; 453(3):393-9. PubMed ID: 23679855
[TBL] [Abstract][Full Text] [Related]
25. Huprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallography.
Ronco C; Carletti E; Colletier JP; Weik M; Nachon F; Jean L; Renard PY
ChemMedChem; 2012 Mar; 7(3):400-5. PubMed ID: 22052791
[No Abstract] [Full Text] [Related]
26. Huprine X is a novel high-affinity inhibitor of acetylcholinesterase that is of interest for treatment of Alzheimer's disease.
Camps P; Cusack B; Mallender WD; El Achab RE; Morral J; Muñoz-Torrero D; Rosenberry TL
Mol Pharmacol; 2000 Feb; 57(2):409-17. PubMed ID: 10648652
[TBL] [Abstract][Full Text] [Related]
27. Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents.
Maqbool M; Manral A; Jameel E; Kumar J; Saini V; Shandilya A; Tiwari M; Hoda N; Jayaram B
Bioorg Med Chem; 2016 Jun; 24(12):2777-88. PubMed ID: 27157006
[TBL] [Abstract][Full Text] [Related]
28. Interest of novel N-alkylpyridinium-indolizine hybrids in the field of Alzheimer's disease: Synthesis, characterization and evaluation of antioxidant activity, cholinesterase inhibition, and amyloid fibrillation interference.
Baussanne I; Firstova O; Dediu AB; Larosa C; Furdui B; Ghinea IO; Thomas A; Chierici S; Dinica R; Demeunynck M
Bioorg Chem; 2021 Nov; 116():105390. PubMed ID: 34670332
[TBL] [Abstract][Full Text] [Related]
29. Design, synthesis, evaluation and molecular modeling study of 4-N-phenylaminoquinolines for Alzheimer disease treatment.
Zhu J; Wang LN; Cai R; Geng SQ; Dong YF; Liu YM
Bioorg Med Chem Lett; 2019 Jun; 29(11):1325-1329. PubMed ID: 30956012
[TBL] [Abstract][Full Text] [Related]
30. Characterisation of the anticholinesterase activity of two new tacrine-huperzine A hybrids.
Alcalá Mdel M; Vivas NM; Hospital S; Camps P; Muñoz-Torrero D; Badia A
Neuropharmacology; 2003 May; 44(6):749-55. PubMed ID: 12681373
[TBL] [Abstract][Full Text] [Related]
31. Novel cinnamamide-dibenzylamine hybrids: Potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease.
Wang J; Cai P; Yang XL; Li F; Wu JJ; Kong LY; Wang XB
Eur J Med Chem; 2017 Oct; 139():68-83. PubMed ID: 28800459
[TBL] [Abstract][Full Text] [Related]
32. Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer's disease.
Rosini M; Simoni E; Bartolini M; Tarozzi A; Matera R; Milelli A; Hrelia P; Andrisano V; Bolognesi ML; Melchiorre C
Eur J Med Chem; 2011 Nov; 46(11):5435-42. PubMed ID: 21924801
[TBL] [Abstract][Full Text] [Related]
33. Synthesis and pharmacological evaluation of huprine-tacrine heterodimers: subnanomolar dual binding site acetylcholinesterase inhibitors.
Camps P; Formosa X; Muñoz-Torrero D; Petrignet J; Badia A; Clos MV
J Med Chem; 2005 Mar; 48(6):1701-4. PubMed ID: 15771413
[TBL] [Abstract][Full Text] [Related]
34. Synthesis and structure-activity relationship of Huprine derivatives as human acetylcholinesterase inhibitors.
Ronco C; Sorin G; Nachon F; Foucault R; Jean L; Romieu A; Renard PY
Bioorg Med Chem; 2009 Jul; 17(13):4523-36. PubMed ID: 19473849
[TBL] [Abstract][Full Text] [Related]
35. Pterostilbene-O-acetamidoalkylbenzylamines derivatives as novel dual inhibitors of cholinesterase with anti-β-amyloid aggregation and antioxidant properties for the treatment of Alzheimer's disease.
Li Y; Qiang X; Li Y; Yang X; Luo L; Xiao G; Cao Z; Tan Z; Deng Y
Bioorg Med Chem Lett; 2016 Apr; 26(8):2035-9. PubMed ID: 26947607
[TBL] [Abstract][Full Text] [Related]
36. Tacrine-resveratrol fused hybrids as multi-target-directed ligands against Alzheimer's disease.
Jeřábek J; Uliassi E; Guidotti L; Korábečný J; Soukup O; Sepsova V; Hrabinova M; Kuča K; Bartolini M; Peña-Altamira LE; Petralla S; Monti B; Roberti M; Bolognesi ML
Eur J Med Chem; 2017 Feb; 127():250-262. PubMed ID: 28064079
[TBL] [Abstract][Full Text] [Related]
37. 3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates.
Dvir H; Wong DM; Harel M; Barril X; Orozco M; Luque FJ; Muñoz-Torrero D; Camps P; Rosenberry TL; Silman I; Sussman JL
Biochemistry; 2002 Mar; 41(9):2970-81. PubMed ID: 11863435
[TBL] [Abstract][Full Text] [Related]
38. New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and β-amyloid-reducing properties.
Fernández-Bachiller MI; Pérez C; Monjas L; Rademann J; Rodríguez-Franco MI
J Med Chem; 2012 Feb; 55(3):1303-17. PubMed ID: 22243648
[TBL] [Abstract][Full Text] [Related]
39. Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
Shan WJ; Huang L; Zhou Q; Meng FC; Li XS
Eur J Med Chem; 2011 Dec; 46(12):5885-93. PubMed ID: 22019228
[TBL] [Abstract][Full Text] [Related]
40. Discovery of indanone derivatives as multi-target-directed ligands against Alzheimer's disease.
Huang L; Miao H; Sun Y; Meng F; Li X
Eur J Med Chem; 2014 Nov; 87():429-39. PubMed ID: 25282266
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]