These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 28632446)

  • 1. Multitarget drug design strategy in Alzheimer's disease: focus on cholinergic transmission and amyloid-β aggregation.
    Simoni E; Bartolini M; Abu IF; Blockley A; Gotti C; Bottegoni G; Caporaso R; Bergamini C; Andrisano V; Cavalli A; Mellor IR; Minarini A; Rosini M
    Future Med Chem; 2017 Jun; 9(10):953-963. PubMed ID: 28632446
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of novel dual acetylcholinesterase inhibitors with antifibrillogenic activity related to Alzheimer's disease.
    de Almeida JR; Figueiro M; Almeida WP; de Paula da Silva CHT
    Future Med Chem; 2018 May; 10(9):1037-1053. PubMed ID: 29676170
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multitarget-directed oxoisoaporphine derivatives: Anti-acetylcholinesterase, anti-β-amyloid aggregation and enhanced autophagy activity against Alzheimer's disease.
    Wei S; Chen W; Qin J; Huangli Y; Wang L; Shen Y; Tang H
    Bioorg Med Chem; 2016 Nov; 24(22):6031-6039. PubMed ID: 27720328
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exploring the Benzazoles Derivatives as Pharmacophores for AChE, BACE1, and as Anti-Aβ Aggregation to Find Multitarget Compounds against Alzheimer's Disease.
    Rosales Hernández MC; Olvera-Valdez M; Velazquez Toledano J; Mendieta Wejebe JE; Fragoso Morales LG; Cruz A
    Molecules; 2024 Oct; 29(19):. PubMed ID: 39407708
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel deoxyvasicinone derivatives as potent multitarget-directed ligands for the treatment of Alzheimer's disease: Design, synthesis, and biological evaluation.
    Ma F; Du H
    Eur J Med Chem; 2017 Nov; 140():118-127. PubMed ID: 28923380
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
    Lan JS; Zhang T; Liu Y; Yang J; Xie SS; Liu J; Miao ZY; Ding Y
    Eur J Med Chem; 2017 Jun; 133():184-196. PubMed ID: 28388521
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rational design, synthesis and biological screening of triazine-triazolopyrimidine hybrids as multitarget anti-Alzheimer agents.
    Jameel E; Meena P; Maqbool M; Kumar J; Ahmed W; Mumtazuddin S; Tiwari M; Hoda N; Jayaram B
    Eur J Med Chem; 2017 Aug; 136():36-51. PubMed ID: 28478343
    [TBL] [Abstract][Full Text] [Related]  

  • 8. New cyclopentaquinoline hybrids with multifunctional capacities for the treatment of Alzheimer's disease.
    Czarnecka K; Girek M; Maciejewska K; Skibiński R; Jończyk J; Bajda M; Kabziński J; Sołowiej P; Majsterek I; Szymański P
    J Enzyme Inhib Med Chem; 2017 Dec; 33(1):158-170. PubMed ID: 29210299
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/butyryl cholinesterase.
    Catto M; Berezin AA; Lo Re D; Loizou G; Demetriades M; De Stradis A; Campagna F; Koutentis PA; Carotti A
    Eur J Med Chem; 2012 Dec; 58():84-97. PubMed ID: 23108363
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biological evaluation of synthetic α,β-unsaturated carbonyl based cyclohexanone derivatives as neuroprotective novel inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
    Zha GF; Zhang CP; Qin HL; Jantan I; Sher M; Amjad MW; Hussain MA; Hussain Z; Bukhari SN
    Bioorg Med Chem; 2016 May; 24(10):2352-9. PubMed ID: 27083471
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and β-amyloid aggregation inhibitors with neuroprotective properties.
    Guzior N; Bajda M; Skrok M; Kurpiewska K; Lewiński K; Brus B; Pišlar A; Kos J; Gobec S; Malawska B
    Eur J Med Chem; 2015 Mar; 92():738-49. PubMed ID: 25621991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer's disease.
    Tseng HJ; Lin MH; Shiao YJ; Yang YC; Chu JC; Chen CY; Chen YY; Lin TE; Su CJ; Pan SL; Chen LC; Wang CY; Hsu KC; Huang WJ
    Eur J Med Chem; 2020 Apr; 192():112193. PubMed ID: 32151835
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and evaluation of multitarget-directed ligands against Alzheimer's disease based on the fusion of donepezil and curcumin.
    Yan J; Hu J; Liu A; He L; Li X; Wei H
    Bioorg Med Chem; 2017 Jun; 25(12):2946-2955. PubMed ID: 28454848
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pterostilbene-O-acetamidoalkylbenzylamines derivatives as novel dual inhibitors of cholinesterase with anti-β-amyloid aggregation and antioxidant properties for the treatment of Alzheimer's disease.
    Li Y; Qiang X; Li Y; Yang X; Luo L; Xiao G; Cao Z; Tan Z; Deng Y
    Bioorg Med Chem Lett; 2016 Apr; 26(8):2035-9. PubMed ID: 26947607
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Perspectives on Inhibiting β-Amyloid Aggregation through Structure-Based Drug Design.
    Mishra P; Ayyannan SR; Panda G
    ChemMedChem; 2015 Sep; 10(9):1467-74. PubMed ID: 26230674
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents.
    Maqbool M; Manral A; Jameel E; Kumar J; Saini V; Shandilya A; Tiwari M; Hoda N; Jayaram B
    Bioorg Med Chem; 2016 Jun; 24(12):2777-88. PubMed ID: 27157006
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Novel Multitarget Hybrid Compounds for the Treatment of Alzheimer's Disease.
    Michalska P; Buendia I; Del Barrio L; Leon R
    Curr Top Med Chem; 2017; 17(9):1027-1043. PubMed ID: 27697052
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New pyridine derivatives as inhibitors of acetylcholinesterase and amyloid aggregation.
    Pandolfi F; De Vita D; Bortolami M; Coluccia A; Di Santo R; Costi R; Andrisano V; Alabiso F; Bergamini C; Fato R; Bartolini M; Scipione L
    Eur J Med Chem; 2017 Dec; 141():197-210. PubMed ID: 29031067
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo.
    Więckowska A; Więckowski K; Bajda M; Brus B; Sałat K; Czerwińska P; Gobec S; Filipek B; Malawska B
    Bioorg Med Chem; 2015 May; 23(10):2445-57. PubMed ID: 25868744
    [TBL] [Abstract][Full Text] [Related]  

  • 20. New racemic annulated pyrazolo[1,2-b]phthalazines as tacrine-like AChE inhibitors with potential use in Alzheimer's disease.
    Jalili-Baleh L; Nadri H; Moradi A; Bukhari SNA; Shakibaie M; Jafari M; Golshani M; Homayouni Moghadam F; Firoozpour L; Asadipour A; Emami S; Khoobi M; Foroumadi A
    Eur J Med Chem; 2017 Oct; 139():280-289. PubMed ID: 28803044
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.