These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 28635296)

  • 1. Benzoxaborole Antimalarial Agents. Part 5. Lead Optimization of Novel Amide Pyrazinyloxy Benzoxaboroles and Identification of a Preclinical Candidate.
    Zhang YK; Plattner JJ; Easom EE; Jacobs RT; Guo D; Freund YR; Berry P; Ciaravino V; Erve JCL; Rosenthal PJ; Campo B; Gamo FJ; Sanz LM; Cao J
    J Med Chem; 2017 Jul; 60(13):5889-5908. PubMed ID: 28635296
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Benzoxaborole antimalarial agents. Part 4. Discovery of potent 6-(2-(alkoxycarbonyl)pyrazinyl-5-oxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles.
    Zhang YK; Plattner JJ; Easom EE; Jacobs RT; Guo D; Sanders V; Freund YR; Campo B; Rosenthal PJ; Bu W; Gamo FJ; Sanz LM; Ge M; Li L; Ding J; Yang Y
    J Med Chem; 2015 Jul; 58(13):5344-54. PubMed ID: 26067904
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and structure-activity relationships of novel benzoxaboroles as a new class of antimalarial agents.
    Zhang YK; Plattner JJ; Freund YR; Easom EE; Zhou Y; Gut J; Rosenthal PJ; Waterson D; Gamo FJ; Angulo-Barturen I; Ge M; Li Z; Li L; Jian Y; Cui H; Wang H; Yang J
    Bioorg Med Chem Lett; 2011 Jan; 21(2):644-51. PubMed ID: 21195617
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Trisubstituted Pyrimidines as Efficacious and Fast-Acting Antimalarials.
    Norcross NR; Baragaña B; Wilson C; Hallyburton I; Osuna-Cabello M; Norval S; Riley J; Stojanovski L; Simeons FR; Porzelle A; Grimaldi R; Wittlin S; Duffy S; Avery VM; Meister S; Sanz L; Jiménez-Díaz B; Angulo-Barturen I; Ferrer S; Martínez MS; Gamo FJ; Frearson JA; Gray DW; Fairlamb AH; Winzeler EA; Waterson D; Campbell SF; Willis P; Read KD; Gilbert IH
    J Med Chem; 2016 Jul; 59(13):6101-20. PubMed ID: 27314305
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Novel Pyrazolopyridine with in Vivo Activity in Plasmodium berghei- and Plasmodium falciparum-Infected Mouse Models from Structure-Activity Relationship Studies around the Core of Recently Identified Antimalarial Imidazopyridazines.
    Le Manach C; Paquet T; Brunschwig C; Njoroge M; Han Z; Gonzàlez Cabrera D; Bashyam S; Dhinakaran R; Taylor D; Reader J; Botha M; Churchyard A; Lauterbach S; Coetzer TL; Birkholtz LM; Meister S; Winzeler EA; Waterson D; Witty MJ; Wittlin S; Jiménez-Díaz MB; Santos Martínez M; Ferrer S; Angulo-Barturen I; Street LJ; Chibale K
    J Med Chem; 2015 Nov; 58(21):8713-22. PubMed ID: 26502160
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Antimalarial benzoheterocyclic 4-aminoquinolines: Structure-activity relationship, in vivo evaluation, mechanistic and bioactivation studies.
    Ongarora DS; Strydom N; Wicht K; Njoroge M; Wiesner L; Egan TJ; Wittlin S; Jurva U; Masimirembwa CM; Chibale K
    Bioorg Med Chem; 2015 Sep; 23(17):5419-32. PubMed ID: 26264839
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protective activity of biflavanones from Garcinia kola against Plasmodium infection.
    Konziase B
    J Ethnopharmacol; 2015 Aug; 172():214-8. PubMed ID: 26129936
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans.
    Malmquist NA; Sundriyal S; Caron J; Chen P; Witkowski B; Menard D; Suwanarusk R; Renia L; Nosten F; Jiménez-Díaz MB; Angulo-Barturen I; Santos Martínez M; Ferrer S; Sanz LM; Gamo FJ; Wittlin S; Duffy S; Avery VM; Ruecker A; Delves MJ; Sinden RE; Fuchter MJ; Scherf A
    Antimicrob Agents Chemother; 2015 Feb; 59(2):950-9. PubMed ID: 25421480
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 3,5-bis(benzylidene)-4-piperidones and related N-acyl analogs: a novel cluster of antimalarials targeting the liver stage of Plasmodium falciparum.
    Das U; Singh RS; Alcorn J; Hickman MR; Sciotti RJ; Leed SE; Lee PJ; Roncal N; Dimmock JR
    Bioorg Med Chem; 2013 Dec; 21(23):7250-6. PubMed ID: 24139941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds.
    Ramachandran S; Hameed P S; Srivastava A; Shanbhag G; Morayya S; Rautela N; Awasthy D; Kavanagh S; Bharath S; Reddy J; Panduga V; Prabhakar KR; Saralaya R; Nanduri R; Raichurkar A; Menasinakai S; Achar V; Jiménez-Díaz MB; Martínez MS; Angulo-Barturen I; Ferrer S; Sanz LM; Gamo FJ; Duffy S; Avery VM; Waterson D; Lee MC; Coburn-Flynn O; Fidock DA; Iyer PS; Narayanan S; Hosagrahara V; Sambandamurthy VK
    J Med Chem; 2014 Aug; 57(15):6642-52. PubMed ID: 25007124
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Docking, synthesis and antimalarial activity of novel 4-anilinoquinoline derivatives.
    Vijayaraghavan S; Mahajan S
    Bioorg Med Chem Lett; 2017 Apr; 27(8):1693-1697. PubMed ID: 28318947
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 3-Hydroxy-propanamidines, a New Class of Orally Active Antimalarials Targeting Plasmodium falciparum.
    Knaab TC; Held J; Burckhardt BB; Rubiano K; Okombo J; Yeo T; Mok S; Uhlemann AC; Lungerich B; Fischli C; Pessanha de Carvalho L; Mordmüller B; Wittlin S; Fidock DA; Kurz T
    J Med Chem; 2021 Mar; 64(6):3035-3047. PubMed ID: 33666415
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue.
    Sonoiki E; Ng CL; Lee MC; Guo D; Zhang YK; Zhou Y; Alley MR; Ahyong V; Sanz LM; Lafuente-Monasterio MJ; Dong C; Schupp PG; Gut J; Legac J; Cooper RA; Gamo FJ; DeRisi J; Freund YR; Fidock DA; Rosenthal PJ
    Nat Commun; 2017 Mar; 8():14574. PubMed ID: 28262680
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antimalarial Benzoxaboroles Target Plasmodium falciparum Leucyl-tRNA Synthetase.
    Sonoiki E; Palencia A; Guo D; Ahyong V; Dong C; Li X; Hernandez VS; Zhang YK; Choi W; Gut J; Legac J; Cooper R; Alley MR; Freund YR; DeRisi J; Cusack S; Rosenthal PJ
    Antimicrob Agents Chemother; 2016 Aug; 60(8):4886-95. PubMed ID: 27270277
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antimalarial activity of novel arylene bis(methylketone) compounds.
    Berger BJ; Paciorkowski A; Suskin M; Dai WW; Cerami A; Ulrich P
    J Infect Dis; 1996 Sep; 174(3):659-62. PubMed ID: 8769633
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles.
    Zhang YK; Plattner JJ; Freund YR; Easom EE; Zhou Y; Ye L; Zhou H; Waterson D; Gamo FJ; Sanz LM; Ge M; Li Z; Li L; Wang H; Cui H
    Bioorg Med Chem Lett; 2012 Feb; 22(3):1299-307. PubMed ID: 22243961
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antimalarial activity and safety assessment of Flueggea virosa leaves and its major constituent with special emphasis on their mode of action.
    Singh SV; Manhas A; Kumar Y; Mishra S; Shanker K; Khan F; Srivastava K; Pal A
    Biomed Pharmacother; 2017 May; 89():761-771. PubMed ID: 28273638
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Characterization of Novel Antimalarial Compound ACT-451840: Preclinical Assessment of Activity and Dose-Efficacy Modeling.
    Le Bihan A; de Kanter R; Angulo-Barturen I; Binkert C; Boss C; Brun R; Brunner R; Buchmann S; Burrows J; Dechering KJ; Delves M; Ewerling S; Ferrer S; Fischli C; Gamo-Benito FJ; Gnädig NF; Heidmann B; Jiménez-Díaz MB; Leroy D; Martínez MS; Meyer S; Moehrle JJ; Ng CL; Noviyanti R; Ruecker A; Sanz LM; Sauerwein RW; Scheurer C; Schleiferboeck S; Sinden R; Snyder C; Straimer J; Wirjanata G; Marfurt J; Price RN; Weller T; Fischli W; Fidock DA; Clozel M; Wittlin S
    PLoS Med; 2016 Oct; 13(10):e1002138. PubMed ID: 27701420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New quinoline derivatives demonstrate a promising antimalarial activity against Plasmodium falciparum in vitro and Plasmodium berghei in vivo.
    Soares RR; da Silva JM; Carlos BC; da Fonseca CC; de Souza LS; Lopes FV; de Paula Dias RM; Moreira PO; Abramo C; Viana GH; de Pila Varotti F; da Silva AD; Scopel KK
    Bioorg Med Chem Lett; 2015 Jun; 25(11):2308-13. PubMed ID: 25920564
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of the antimalarial activity of new compounds against Plasmodium falciparum in vitro, and Plasmodium berghei in vivo.
    Tedlaouti F; Gasquet M; Delmas F; Timon-David P; Madadi NE; Vanelle P; Maldonado J
    J Pharm Belg; 1990; 45(5):306-10. PubMed ID: 2086754
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.