These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

269 related articles for article (PubMed ID: 28636670)

  • 1. Identification of novel small molecules that inhibit STAT3-dependent transcription and function.
    Kolosenko I; Yu Y; Busker S; Dyczynski M; Liu J; Haraldsson M; Palm Apergi C; Helleday T; Tamm KP; Page BDG; Grander D
    PLoS One; 2017; 12(6):e0178844. PubMed ID: 28636670
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of STAT1 and STAT3 specific inhibitors using comparative virtual screening and docking validation.
    Szelag M; Czerwoniec A; Wesoly J; Bluyssen HA
    PLoS One; 2015; 10(2):e0116688. PubMed ID: 25710482
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Small-molecule compounds targeting the STAT3 DNA-binding domain suppress survival of cisplatin-resistant human ovarian cancer cells by inducing apoptosis.
    Huang W; Liu Y; Wang J; Yuan X; Jin HW; Zhang LR; Zhang JT; Liu ZM; Cui JR
    Eur J Med Chem; 2018 Sep; 157():887-897. PubMed ID: 30145375
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SD-1029 inhibits signal transducer and activator of transcription 3 nuclear translocation.
    Duan Z; Bradner JE; Greenberg E; Levine R; Foster R; Mahoney J; Seiden MV
    Clin Cancer Res; 2006 Nov; 12(22):6844-52. PubMed ID: 17121906
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and activity of novel 2,6-disubstituted purine derivatives, potential small molecule inhibitors of signal transducer and activator of transcription 3.
    Wang X; He Q; Wu K; Guo T; Du X; Zhang H; Fang L; Zheng N; Zhang Q; Ye F
    Eur J Med Chem; 2019 Oct; 179():218-232. PubMed ID: 31254923
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Strategies and Approaches of Targeting STAT3 for Cancer Treatment.
    Furtek SL; Backos DS; Matheson CJ; Reigan P
    ACS Chem Biol; 2016 Feb; 11(2):308-18. PubMed ID: 26730496
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Signal Transducer and Activator of Transcription Protein 3 (STAT3): An Update on its Direct Inhibitors as Promising Anticancer Agents.
    Gelain A; Mori M; Meneghetti F; Villa S
    Curr Med Chem; 2019; 26(27):5165-5206. PubMed ID: 30027840
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The IκB Kinase Inhibitor ACHP Targets the STAT3 Signaling Pathway in Human Non-Small Cell Lung Carcinoma Cells.
    Lee JH; Mohan CD; Basappa S; Rangappa S; Chinnathambi A; Alahmadi TA; Alharbi SA; Kumar AP; Sethi G; Ahn KS; Rangappa KS
    Biomolecules; 2019 Dec; 9(12):. PubMed ID: 31847229
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Screening and biological evaluation of a novel STAT3 signaling pathway inhibitor against cancer.
    Huang M; Chen Z; Zhang L; Huang Z; Chen Y; Xu J; Zhang J; Shu X
    Bioorg Med Chem Lett; 2016 Nov; 26(21):5172-5176. PubMed ID: 27727126
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Discovery of novel inhibitors of signal transducer and activator of transcription 3 (STAT3) signaling pathway by virtual screening.
    Zhang M; Zhu W; Li Y
    Eur J Med Chem; 2013 Apr; 62():301-10. PubMed ID: 23376248
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification and characterization of small molecule inhibitors of signal transducer and activator of transcription 3 (STAT3) signaling pathway by virtual screening.
    Zhang M; Zhu W; Ding N; Zhang W; Li Y
    Bioorg Med Chem Lett; 2013 Apr; 23(7):2225-9. PubMed ID: 23434226
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rational drug design of benzothiazole-based derivatives as potent signal transducer and activator of transcription 3 (STAT3) signaling pathway inhibitors.
    Gao D; Jin N; Fu Y; Zhu Y; Wang Y; Wang T; Chen Y; Zhang M; Xiao Q; Huang M; Li Y
    Eur J Med Chem; 2021 Apr; 216():113333. PubMed ID: 33689932
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Antitumor activity of novel pyrazole-based small molecular inhibitors of the STAT3 pathway in patient derived high grade glioma cells.
    Zhang L; Peterson TE; Lu VM; Parney IF; Daniels DJ
    PLoS One; 2019; 14(7):e0220569. PubMed ID: 31361777
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-based discovery of potent and selective small-molecule inhibitors targeting signal transducer and activator of transcription 3 (STAT3).
    Huang Q; Zhong Y; Li B; Ouyang S; Deng L; Mo J; Shi S; Lv N; Wu R; Liu P; Hu W; Zhang X; Wang Y
    Eur J Med Chem; 2021 Oct; 221():113525. PubMed ID: 34000483
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Discovery of novel STAT3 small molecule inhibitors via in silico site-directed fragment-based drug design.
    Yu W; Xiao H; Lin J; Li C
    J Med Chem; 2013 Jun; 56(11):4402-12. PubMed ID: 23651330
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small molecule inhibitors of STAT3 for cancer therapy.
    Zhao M; Jiang B; Gao FH
    Curr Med Chem; 2011; 18(26):4012-8. PubMed ID: 21824090
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells.
    Duan Z; Bradner J; Greenberg E; Mazitschek R; Foster R; Mahoney J; Seiden MV
    Mol Pharmacol; 2007 Nov; 72(5):1137-45. PubMed ID: 17675586
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel aminotetrazole derivatives as selective STAT3 non-peptide inhibitors.
    Pallandre JR; Borg C; Rognan D; Boibessot T; Luzet V; Yesylevskyy S; Ramseyer C; Pudlo M
    Eur J Med Chem; 2015 Oct; 103():163-74. PubMed ID: 26352675
    [TBL] [Abstract][Full Text] [Related]  

  • 19. High-content pSTAT3/1 imaging assays to screen for selective inhibitors of STAT3 pathway activation in head and neck cancer cell lines.
    Johnston PA; Sen M; Hua Y; Camarco D; Shun TY; Lazo JS; Grandis JR
    Assay Drug Dev Technol; 2014; 12(1):55-79. PubMed ID: 24127660
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Preclinical characterization of signal transducer and activator of transcription 3 small molecule inhibitors for primary and metastatic brain cancer therapy.
    Assi HH; Paran C; VanderVeen N; Savakus J; Doherty R; Petruzzella E; Hoeschele JD; Appelman H; Raptis L; Mikkelsen T; Lowenstein PR; Castro MG
    J Pharmacol Exp Ther; 2014 Jun; 349(3):458-69. PubMed ID: 24696041
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.