BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

225 related articles for article (PubMed ID: 28644464)

  • 1. A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrations.
    Busschaert N; Park SH; Baek KH; Choi YP; Park J; Howe ENW; Hiscock JR; Karagiannidis LE; Marques I; Félix V; Namkung W; Sessler JL; Gale PA; Shin I
    Nat Chem; 2017 Jul; 9(7):667-675. PubMed ID: 28644464
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthetic ion transporters can induce apoptosis by facilitating chloride anion transport into cells.
    Ko SK; Kim SK; Share A; Lynch VM; Park J; Namkung W; Van Rossom W; Busschaert N; Gale PA; Sessler JL; Shin I
    Nat Chem; 2014 Oct; 6(10):885-92. PubMed ID: 25242483
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and biological evaluation of aza-crown ether-squaramide conjugates as anion/cation symporters.
    Yu XH; Cai XJ; Hong XQ; Tam KY; Zhang K; Chen WH
    Future Med Chem; 2019 May; 11(10):1091-1106. PubMed ID: 31280669
    [No Abstract]   [Full Text] [Related]  

  • 4. Quinine-Based Semisynthetic Ion Transporters with Potential Antiproliferative Activities.
    Akhtar N; Pradhan N; Barik GK; Chatterjee S; Ghosh S; Saha A; Satpati P; Bhattacharyya A; Santra MK; Manna D
    ACS Appl Mater Interfaces; 2020 Jun; 12(23):25521-25533. PubMed ID: 32425038
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tripodal squaramide conjugates as highly effective transmembrane anion transporters.
    Cai XJ; Li Z; Chen WH
    Bioorg Med Chem Lett; 2017 May; 27(9):1999-2002. PubMed ID: 28325602
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Benzohydrazide-Based Artificial Ion Channel that Modulates Chloride Ion Concentration in Cancer Cells and Induces Apoptosis by Disruption of Autophagy.
    Mondal A; Save SN; Sarkar S; Mondal D; Mondal J; Sharma S; Talukdar P
    J Am Chem Soc; 2023 May; 145(17):9737-9745. PubMed ID: 37021819
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Diphenylethylenediamine-Based Potent Anionophores: Transmembrane Chloride Ion Transport and Apoptosis Inducing Activities.
    Akhtar N; Saha A; Kumar V; Pradhan N; Panda S; Morla S; Kumar S; Manna D
    ACS Appl Mater Interfaces; 2018 Oct; 10(40):33803-33813. PubMed ID: 30221925
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytosolic chloride ion is a key factor in lysosomal acidification and function of autophagy in human gastric cancer cell.
    Hosogi S; Kusuzaki K; Inui T; Wang X; Marunaka Y
    J Cell Mol Med; 2014 Jun; 18(6):1124-33. PubMed ID: 24725767
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Full elucidation of the transmembrane anion transport mechanism of squaramides using in silico investigations.
    Marques I; Costa PMR; Q Miranda M; Busschaert N; Howe ENW; Clarke HJ; Haynes CJE; Kirby IL; Rodilla AM; Pérez-Tomás R; Gale PA; Félix V
    Phys Chem Chem Phys; 2018 Aug; 20(32):20796-20811. PubMed ID: 29978159
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Determinants of Ion-Transporter Cancer Cell Death.
    Park SH; Park SH; Howe ENW; Hyun JY; Chen LJ; Hwang I; Vargas-Zuñiga G; Busschaert N; Gale PA; Sessler JL; Shin I
    Chem; 2019 Aug; 5(8):2079-2098. PubMed ID: 33791443
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Chloride Transport through Supramolecular Barrel-Rosette Ion Channels: Lipophilic Control and Apoptosis-Inducing Activity.
    Saha T; Gautam A; Mukherjee A; Lahiri M; Talukdar P
    J Am Chem Soc; 2016 Dec; 138(50):16443-16451. PubMed ID: 27933857
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Silver Nanoparticle-Induced Autophagic-Lysosomal Disruption and NLRP3-Inflammasome Activation in HepG2 Cells Is Size-Dependent.
    Mishra AR; Zheng J; Tang X; Goering PL
    Toxicol Sci; 2016 Apr; 150(2):473-87. PubMed ID: 26801583
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Squaramides as novel class I and IIB histone deacetylase inhibitors for topical treatment of cutaneous t-cell lymphoma.
    Fournier JF; Bhurruth-Alcor Y; Musicki B; Aubert J; Aurelly M; Bouix-Peter C; Bouquet K; Chantalat L; Delorme M; Drean B; Duvert G; Fleury-Bregeot N; Gauthier B; Grisendi K; Harris CS; Hennequin LF; Isabet T; Joly F; Lafitte G; Millois C; Morgentin R; Pascau J; Piwnica D; Rival Y; Soulet C; Thoreau É; Tomas L
    Bioorg Med Chem Lett; 2018 Sep; 28(17):2985-2992. PubMed ID: 30122227
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Autophagy Attenuates MnCl2-induced Apoptosis in Human Bronchial Epithelial Cells.
    Yuan Z; Ying XP; Zhong WJ; Tian SM; Wang Y; Jia YR; Chen W; Fu JL; Zhao P; Zhou ZC
    Biomed Environ Sci; 2016 Jul; 29(7):494-504. PubMed ID: 27554119
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fluorinated bisbenzimidazoles: a new class of drug-like anion transporters with chloride-mediated, cell apoptosis-inducing activity.
    Yu XH; Hong XQ; Chen WH
    Org Biomol Chem; 2019 Feb; 17(6):1558-1571. PubMed ID: 30694281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Facile synthesis of autophagonizer and evaluation of its activity to induce autophagic cell death in apoptosis-defective cell line.
    Nguyen J; Chen L; Kumar D; Lee J
    Bioorg Med Chem Lett; 2016 Oct; 26(19):4753-4756. PubMed ID: 27597252
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impaired lysosomal activity mediated autophagic flux disruption by graphite carbon nanofibers induce apoptosis in human lung epithelial cells through oxidative stress and energetic impairment.
    Mittal S; Sharma PK; Tiwari R; Rayavarapu RG; Shankar J; Chauhan LKS; Pandey AK
    Part Fibre Toxicol; 2017 Apr; 14(1):15. PubMed ID: 28454554
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, anionophoric activity and apoptosis-inducing bioactivity of benzimidazolyl-based transmembrane anion transporters.
    Yu XH; Peng CC; Sun XX; Chen WH
    Eur J Med Chem; 2018 May; 152():115-125. PubMed ID: 29702447
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthetic tambjamine analogues induce mitochondrial swelling and lysosomal dysfunction leading to autophagy blockade and necrotic cell death in lung cancer.
    Rodilla AM; Korrodi-Gregório L; Hernando E; Manuel-Manresa P; Quesada R; Pérez-Tomás R; Soto-Cerrato V
    Biochem Pharmacol; 2017 Feb; 126():23-33. PubMed ID: 27890727
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Initial autophagic protection switches to disruption of autophagic flux by lysosomal instability during cadmium stress accrual in renal NRK-52E cells.
    Lee WK; Probst S; Santoyo-Sánchez MP; Al-Hamdani W; Diebels I; von Sivers JK; Kerek E; Prenner EJ; Thévenod F
    Arch Toxicol; 2017 Oct; 91(10):3225-3245. PubMed ID: 28321485
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.