BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

232 related articles for article (PubMed ID: 28644886)

  • 1. Complex I inhibition augments dichloroacetate cytotoxicity through enhancing oxidative stress in VM-M3 glioblastoma cells.
    Ward NP; Poff AM; Koutnik AP; D'Agostino DP
    PLoS One; 2017; 12(6):e0180061. PubMed ID: 28644886
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting Cancer Cell Metabolism with Metformin, Dichloroacetate and Memantine in Glioblastoma (GBM).
    Albayrak G; Konac E; Dere UA; Emmez H
    Turk Neurosurg; 2021; 31(2):233-237. PubMed ID: 33372258
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dual-targeting of aberrant glucose metabolism in glioblastoma.
    Shen H; Decollogne S; Dilda PJ; Hau E; Chung SA; Luk PP; Hogg PJ; McDonald KL
    J Exp Clin Cancer Res; 2015 Feb; 34(1):14. PubMed ID: 25652202
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sensitization of metformin-cytotoxicity by dichloroacetate via reprogramming glucose metabolism in cancer cells.
    Choi YW; Lim IK
    Cancer Lett; 2014 May; 346(2):300-8. PubMed ID: 24480191
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metformin enhances antitumor action of sodium dichloroacetate against glioma C6.
    Kolesnik DL; Pyaskovskaya ON; Yurchenko OV; Solyanik GI
    Exp Oncol; 2019 Jun; 41(2):123-129. PubMed ID: 31262158
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metformin enhances cytotoxic action of dichloroacetate against Lewis lung carcinoma cells in vitro.
    Kolesnik DL; Pyaskovskaya ON; Gorbach O; Solyanik GI
    Exp Oncol; 2020 Mar; 42(1):35-39. PubMed ID: 32231186
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolic modulation of glioblastoma with dichloroacetate.
    Michelakis ED; Sutendra G; Dromparis P; Webster L; Haromy A; Niven E; Maguire C; Gammer TL; Mackey JR; Fulton D; Abdulkarim B; McMurtry MS; Petruk KC
    Sci Transl Med; 2010 May; 2(31):31ra34. PubMed ID: 20463368
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Metabolic-targeted Combination Therapy With Dichloroacetate and Metformin Suppresses Glioblastoma Cell Line Growth
    Korsakova L; Krasko JA; Stankevicius E
    In Vivo; 2021; 35(1):341-348. PubMed ID: 33402483
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Time-dependent cytotoxicity of dichloroacetate and metformin against Lewis lung carcinoma.
    Kolesnik DL; Pyaskovskaya ON; Yakshibaeva YR; Solyanik GI
    Exp Oncol; 2019 Mar; 41(1):14-19. PubMed ID: 30932416
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metformin and Dichloroacetate Suppress Proliferation of Liver Cancer Cells by Inhibiting mTOR Complex 1.
    Kim TS; Lee M; Park M; Kim SY; Shim MS; Lee CY; Choi DH; Cho Y
    Int J Mol Sci; 2021 Sep; 22(18):. PubMed ID: 34576192
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Methyl succinate antagonises biguanide-induced AMPK-activation and death of pancreatic beta-cells through restoration of mitochondrial electron transfer.
    Hinke SA; Martens GA; Cai Y; Finsi J; Heimberg H; Pipeleers D; Van de Casteele M
    Br J Pharmacol; 2007 Apr; 150(8):1031-43. PubMed ID: 17339833
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dichloroacetate induced intracellular acidification in glioblastoma: in vivo detection using AACID-CEST MRI at 9.4 Tesla.
    Albatany M; Li A; Meakin S; Bartha R
    J Neurooncol; 2018 Jan; 136(2):255-262. PubMed ID: 29143921
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dichloroacetate enhances apoptotic cell death via oxidative damage and attenuates lactate production in metformin-treated breast cancer cells.
    Haugrud AB; Zhuang Y; Coppock JD; Miskimins WK
    Breast Cancer Res Treat; 2014 Oct; 147(3):539-50. PubMed ID: 25212175
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metformin protects endothelial function in diet-induced obese mice by inhibition of endoplasmic reticulum stress through 5' adenosine monophosphate-activated protein kinase-peroxisome proliferator-activated receptor δ pathway.
    Cheang WS; Tian XY; Wong WT; Lau CW; Lee SS; Chen ZY; Yao X; Wang N; Huang Y
    Arterioscler Thromb Vasc Biol; 2014 Apr; 34(4):830-6. PubMed ID: 24482374
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Local delivery of cancer-cell glycolytic inhibitors in high-grade glioma.
    Wicks RT; Azadi J; Mangraviti A; Zhang I; Hwang L; Joshi A; Bow H; Hutt-Cabezas M; Martin KL; Rudek MA; Zhao M; Brem H; Tyler BM
    Neuro Oncol; 2015 Jan; 17(1):70-80. PubMed ID: 25053853
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of mitochondrial oxidation by PDK2 inhibition reverses cisplatin resistance in head and neck cancer.
    Roh JL; Park JY; Kim EH; Jang HJ; Kwon M
    Cancer Lett; 2016 Feb; 371(1):20-9. PubMed ID: 26607904
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC.
    Stockwin LH; Yu SX; Borgel S; Hancock C; Wolfe TL; Phillips LR; Hollingshead MG; Newton DL
    Int J Cancer; 2010 Dec; 127(11):2510-9. PubMed ID: 20533281
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metformin suppresses glucose-6-phosphatase expression by a complex I inhibition and AMPK activation-independent mechanism.
    Ota S; Horigome K; Ishii T; Nakai M; Hayashi K; Kawamura T; Kishino A; Taiji M; Kimura T
    Biochem Biophys Res Commun; 2009 Oct; 388(2):311-6. PubMed ID: 19664596
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antitumor and chemosensitizing action of dichloroacetate implicates modulation of tumor microenvironment: a role of reorganized glucose metabolism, cell survival regulation and macrophage differentiation.
    Kumar A; Kant S; Singh SM
    Toxicol Appl Pharmacol; 2013 Nov; 273(1):196-208. PubMed ID: 24051182
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dichloroacetate is an antimetabolite that antagonizes acetate and deprives cancer cells from its benefits: A novel evidence-based medical hypothesis.
    El Sayed SM; Baghdadi H; Ahmed NS; Almaramhy HH; Mahmoud AA; El-Sawy SA; Ayat M; Elshazley M; Abdel-Aziz W; Abdel-Latif HM; Ibrahim W; Aboonq MS
    Med Hypotheses; 2019 Jan; 122():206-209. PubMed ID: 30593413
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.