465 related articles for article (PubMed ID: 28645575)
1. Prediction of drug-induced immune-mediated hepatotoxicity using hepatocyte-like cells derived from human embryonic stem cells.
Kim DE; Jang MJ; Kim YR; Lee JY; Cho EB; Kim E; Kim Y; Kim MY; Jeong WI; Kim S; Han YM; Lee SH
Toxicology; 2017 Jul; 387():1-9. PubMed ID: 28645575
[TBL] [Abstract][Full Text] [Related]
2. Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.
Gómez-Lechón MJ; Tolosa L
Arch Toxicol; 2016 Sep; 90(9):2049-2061. PubMed ID: 27325232
[TBL] [Abstract][Full Text] [Related]
3. Usefulness of in vitro combination assays of mitochondrial dysfunction and apoptosis for the estimation of potential risk of idiosyncratic drug induced liver injury.
Goda K; Takahashi T; Kobayashi A; Shoda T; Kuno H; Sugai S
J Toxicol Sci; 2016; 41(5):605-15. PubMed ID: 27665770
[TBL] [Abstract][Full Text] [Related]
4. In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.
Utkarsh D; Loretz C; Li AP
Chem Biol Interact; 2016 Aug; 255():12-22. PubMed ID: 26718876
[TBL] [Abstract][Full Text] [Related]
5. Prediction of Drug-Induced Liver Injury in Micropatterned Co-cultures Containing iPSC-Derived Human Hepatocytes.
Ware BR; Berger DR; Khetani SR
Toxicol Sci; 2015 Jun; 145(2):252-62. PubMed ID: 25716675
[TBL] [Abstract][Full Text] [Related]
6. MicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity.
Kia R; Kelly L; Sison-Young RL; Zhang F; Pridgeon CS; Heslop JA; Metcalfe P; Kitteringham NR; Baxter M; Harrison S; Hanley NA; Burke ZD; Storm MP; Welham MJ; Tosh D; Küppers-Munther B; Edsbagge J; Starkey Lewis PJ; Bonner F; Harpur E; Sidaway J; Bowes J; Fenwick SW; Malik H; Goldring CE; Park BK
Toxicol Sci; 2015 Mar; 144(1):173-85. PubMed ID: 25527335
[TBL] [Abstract][Full Text] [Related]
7. Sensitivities of gel entrapped hepatocytes in hollow fibers to hepatotoxic drug.
Meng Q; Zhang G; Shen C; Qiu H
Toxicol Lett; 2006 Sep; 166(1):19-26. PubMed ID: 16814964
[TBL] [Abstract][Full Text] [Related]
8. Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity.
Choudhury Y; Toh YC; Xing J; Qu Y; Poh J; Li H; Tan HS; Kanesvaran R; Yu H; Tan MH
Sci Rep; 2017 Jan; 7():41238. PubMed ID: 28120901
[TBL] [Abstract][Full Text] [Related]
9. Morphological and Functional Characterization and Assessment of iPSC-Derived Hepatocytes for In Vitro Toxicity Testing.
Lu J; Einhorn S; Venkatarangan L; Miller M; Mann DA; Watkins PB; LeCluyse E
Toxicol Sci; 2015 Sep; 147(1):39-54. PubMed ID: 26092927
[TBL] [Abstract][Full Text] [Related]
10. CHOP is a critical regulator of acetaminophen-induced hepatotoxicity.
Uzi D; Barda L; Scaiewicz V; Mills M; Mueller T; Gonzalez-Rodriguez A; Valverde AM; Iwawaki T; Nahmias Y; Xavier R; Chung RT; Tirosh B; Shibolet O
J Hepatol; 2013 Sep; 59(3):495-503. PubMed ID: 23665281
[TBL] [Abstract][Full Text] [Related]
11. Hepatotoxicants induce cytokine imbalance in response to innate immune system.
Goto S; Deguchi J; Nishio N; Nomura N; Funabashi H
J Toxicol Sci; 2015 Jun; 40(3):389-404. PubMed ID: 25972199
[TBL] [Abstract][Full Text] [Related]
12. Stem-cell derived hepatocyte-like cells for the assessment of drug-induced liver injury.
Donato MT; Tolosa L
Differentiation; 2019; 106():15-22. PubMed ID: 30844688
[TBL] [Abstract][Full Text] [Related]
13. Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems.
Rodrigues RM; Heymans A; De Boe V; Sachinidis A; Chaudhari U; Govaere O; Roskams T; Vanhaecke T; Rogiers V; De Kock J
Toxicol Lett; 2016 Jan; 240(1):50-9. PubMed ID: 26497421
[TBL] [Abstract][Full Text] [Related]
14. Role of caspase-8 and/or -9 as biomarkers that can distinguish the potential to cause toxic- and immune related-adverse event, for the progress of acetaminophen-induced liver injury.
Noda T; Kato R; Hattori T; Furukawa Y; Ijiri Y; Tanaka K
Life Sci; 2022 Apr; 294():120351. PubMed ID: 35092733
[TBL] [Abstract][Full Text] [Related]
15. Toxicity monitoring with primary cultured hepatocytes underestimates the acetaminophen-induced inflammatory responses of the mouse liver.
Tachibana S; Shimomura A; Inadera H
Tohoku J Exp Med; 2011 Dec; 225(4):263-72. PubMed ID: 22083109
[TBL] [Abstract][Full Text] [Related]
16. Long-enduring primary hepatocyte-based co-cultures improve prediction of hepatotoxicity.
Novik EI; Dwyer J; Morelli JK; Parekh A; Cho C; Pludwinski E; Shrirao A; Freedman RM; MacDonald JS; Jayyosi Z
Toxicol Appl Pharmacol; 2017 Dec; 336():20-30. PubMed ID: 28942002
[TBL] [Abstract][Full Text] [Related]
17. Drug-Induced Liver Injury: Cascade of Events Leading to Cell Death, Apoptosis or Necrosis.
Iorga A; Dara L; Kaplowitz N
Int J Mol Sci; 2017 May; 18(5):. PubMed ID: 28486401
[TBL] [Abstract][Full Text] [Related]
18. M1 muscarinic receptors modify oxidative stress response to acetaminophen-induced acute liver injury.
Urrunaga NH; Jadeja RN; Rachakonda V; Ahmad D; McLean LP; Cheng K; Shah V; Twaddell WS; Raufman JP; Khurana S
Free Radic Biol Med; 2015 Jan; 78():66-81. PubMed ID: 25452146
[TBL] [Abstract][Full Text] [Related]
19. Investigating acetaminophen hepatotoxicity in multi-cellular organotypic liver models.
Orbach SM; Cassin ME; Ehrich MF; Rajagopalan P
Toxicol In Vitro; 2017 Aug; 42():10-20. PubMed ID: 28330786
[TBL] [Abstract][Full Text] [Related]
20. Dissecting the molecular pathophysiology of drug-induced liver injury.
Ye H; Nelson LJ; Gómez Del Moral M; Martínez-Naves E; Cubero FJ
World J Gastroenterol; 2018 Apr; 24(13):1373-1385. PubMed ID: 29632419
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]