146 related articles for article (PubMed ID: 28651225)
1. Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies.
Qian HY; Wang ZL; Xie XY; Pan YL; Li GJ; Xie X; Chen JZ
Eur J Med Chem; 2017 Sep; 137():598-611. PubMed ID: 28651225
[TBL] [Abstract][Full Text] [Related]
2. Synthesis, Pharmacological Evaluation, and Docking Studies of Novel Pyridazinone-Based Cannabinoid Receptor Type 2 Ligands.
Ragusa G; Bencivenni S; Morales P; Callaway T; Hurst DP; Asproni B; Merighi S; Loriga G; Pinna GA; Reggio PH; Gessi S; Murineddu G
ChemMedChem; 2018 Jun; 13(11):1102-1114. PubMed ID: 29575721
[TBL] [Abstract][Full Text] [Related]
3. Design, Synthesis, and SAR Studies of Heteroarylpyrimidines and Heteroaryltriazines as CB
Qian HY; Wang ZL; Chen LL; Pan YL; Xie XY; Xie X; Chen JZ
ChemMedChem; 2018 Nov; 13(22):2455-2463. PubMed ID: 30246417
[TBL] [Abstract][Full Text] [Related]
4. New pyridazinone-4-carboxamides as new cannabinoid receptor type-2 inverse agonists: Synthesis, pharmacological data and molecular docking.
Ragusa G; Gómez-Cañas M; Morales P; Rodríguez-Cueto C; Pazos MR; Asproni B; Cichero E; Fossa P; Pinna GA; Jagerovic N; Fernández-Ruiz J; Murineddu G
Eur J Med Chem; 2017 Feb; 127():398-412. PubMed ID: 28088085
[TBL] [Abstract][Full Text] [Related]
5. Design, syntheses, structure-activity relationships and docking studies of coumarin derivatives as novel selective ligands for the CB2 receptor.
Han S; Zhang FF; Qian HY; Chen LL; Pu JB; Xie X; Chen JZ
Eur J Med Chem; 2015 Mar; 93():16-32. PubMed ID: 25644673
[TBL] [Abstract][Full Text] [Related]
6. Tricyclic pyrazoles. Part 8. Synthesis, biological evaluation and modelling of tricyclic pyrazole carboxamides as potential CB2 receptor ligands with antagonist/inverse agonist properties.
Deiana V; Gómez-Cañas M; Pazos MR; Fernández-Ruiz J; Asproni B; Cichero E; Fossa P; Muñoz E; Deligia F; Murineddu G; García-Arencibia M; Pinna GA
Eur J Med Chem; 2016 Apr; 112():66-80. PubMed ID: 26890113
[TBL] [Abstract][Full Text] [Related]
7. Novel sulfenamides and sulfonamides based on pyridazinone and pyridazine scaffolds as CB
Murineddu G; Deligia F; Ragusa G; García-Toscano L; Gómez-Cañas M; Asproni B; Satta V; Cichero E; Pazos R; Fossa P; Loriga G; Fernández-Ruiz J; Pinna GA
Bioorg Med Chem; 2018 Jan; 26(1):295-307. PubMed ID: 29229226
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and evaluation of 3-amino-6-aryl-pyridazines as selective CB(2) agonists for the treatment of inflammatory pain.
Gleave RJ; Beswick PJ; Brown AJ; Giblin GM; Goldsmith P; Haslam CP; Mitchell WL; Nicholson NH; Page LW; Patel S; Roomans S; Slingsby BP; Swarbrick ME
Bioorg Med Chem Lett; 2010 Jan; 20(2):465-8. PubMed ID: 20005703
[TBL] [Abstract][Full Text] [Related]
9. Discovery and optimization of a novel series of N-arylamide oxadiazoles as potent, highly selective and orally bioavailable cannabinoid receptor 2 (CB2) agonists.
Cheng Y; Albrecht BK; Brown J; Buchanan JL; Buckner WH; DiMauro EF; Emkey R; Fremeau RT; Harmange JC; Hoffman BJ; Huang L; Huang M; Lee JH; Lin FF; Martin MW; Nguyen HQ; Patel VF; Tomlinson SA; White RD; Xia X; Hitchcock SA
J Med Chem; 2008 Aug; 51(16):5019-34. PubMed ID: 18680277
[TBL] [Abstract][Full Text] [Related]
10. Selective CB2 agonists with anti-pruritic activity: discovery of potent and orally available bicyclic 2-pyridones.
Kusakabe K; Iso Y; Tada Y; Sakagami M; Morioka Y; Chomei N; Shinonome S; Kawamoto K; Takenaka H; Yasui K; Hamana H; Hanasaki K
Bioorg Med Chem; 2013 Jun; 21(11):3154-63. PubMed ID: 23623258
[TBL] [Abstract][Full Text] [Related]
11. Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis.
Shi Y; Duan YH; Ji YY; Wang ZL; Wu YR; Gunosewoyo H; Xie XY; Chen JZ; Yang F; Li J; Tang J; Xie X; Yu LF
J Med Chem; 2017 Aug; 60(16):7067-7083. PubMed ID: 28726401
[TBL] [Abstract][Full Text] [Related]
12. Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist.
Brizzi A; Aiello F; Marini P; Cascio MG; Corelli F; Brizzi V; De Petrocellis L; Ligresti A; Luongo L; Lamponi S; Maione S; Pertwee RG; Di Marzo V
Bioorg Med Chem; 2014 Sep; 22(17):4770-83. PubMed ID: 25065940
[TBL] [Abstract][Full Text] [Related]
13. Structure-activity relationships of substituted 1H-indole-2-carboxamides as CB1 receptor allosteric modulators.
Nguyen T; German N; Decker AM; Li JX; Wiley JL; Thomas BF; Kenakin TP; Zhang Y
Bioorg Med Chem; 2015 May; 23(9):2195-2203. PubMed ID: 25797163
[TBL] [Abstract][Full Text] [Related]
14. Design and synthesis of a novel series of N-alkyl isatin acylhydrazone derivatives that act as selective cannabinoid receptor 2 agonists for the treatment of neuropathic pain.
Diaz P; Xu J; Astruc-Diaz F; Pan HM; Brown DL; Naguib M
J Med Chem; 2008 Aug; 51(16):4932-47. PubMed ID: 18666769
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of (3',5'-dichloro-2,6-dihydroxy-biphenyl-4-yl)-aryl/alkyl-methanone selective CB2 inverse agonist.
Presley CS; Mustafa SM; Abidi AH; Moore BM
Bioorg Med Chem; 2015 Sep; 23(17):5390-401. PubMed ID: 26275680
[TBL] [Abstract][Full Text] [Related]
16. Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors.
Pasquini S; De Rosa M; Ligresti A; Mugnaini C; Brizzi A; Caradonna NP; Cascio MG; Bolognini D; Pertwee RG; Di Marzo V; Corelli F
Eur J Med Chem; 2012 Dec; 58():30-43. PubMed ID: 23085772
[TBL] [Abstract][Full Text] [Related]
17. Discovery of novel Tetrahydrobenzo[b]thiophene and pyrrole based scaffolds as potent and selective CB2 receptor ligands: The structural elements controlling binding affinity, selectivity and functionality.
Osman NA; Ligresti A; Klein CD; Allarà M; Rabbito A; Di Marzo V; Abouzid KA; Abadi AH
Eur J Med Chem; 2016 Oct; 122():619-634. PubMed ID: 27448919
[TBL] [Abstract][Full Text] [Related]
18. Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands.
Bertini S; Parkkari T; Savinainen JR; Arena C; Saccomanni G; Saguto S; Ligresti A; Allarà M; Bruno A; Marinelli L; Di Marzo V; Novellino E; Manera C; Macchia M
Eur J Med Chem; 2015 Jan; 90():526-36. PubMed ID: 25486424
[TBL] [Abstract][Full Text] [Related]
19. Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands.
Pasquini S; Ligresti A; Mugnaini C; Semeraro T; Cicione L; De Rosa M; Guida F; Luongo L; De Chiaro M; Cascio MG; Bolognini D; Marini P; Pertwee R; Maione S; Di Marzo V; Corelli F
J Med Chem; 2010 Aug; 53(16):5915-28. PubMed ID: 20718492
[TBL] [Abstract][Full Text] [Related]
20. CB2-selective cannabinoid receptor ligands: synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides.
Lucchesi V; Hurst DP; Shore DM; Bertini S; Ehrmann BM; Allarà M; Lawrence L; Ligresti A; Minutolo F; Saccomanni G; Sharir H; Macchia M; Di Marzo V; Abood ME; Reggio PH; Manera C
J Med Chem; 2014 Nov; 57(21):8777-91. PubMed ID: 25272206
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
