212 related articles for article (PubMed ID: 28655862)
1. Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.
Li B; Orton D; Neitzel LR; Astudillo L; Shen C; Long J; Chen X; Kirkbride KC; Doundoulakis T; Guerra ML; Zaias J; Fei DL; Rodriguez-Blanco J; Thorne C; Wang Z; Jin K; Nguyen DM; Sands LR; Marchetti F; Abreu MT; Cobb MH; Capobianco AJ; Lee E; Robbins DJ
Sci Signal; 2017 Jun; 10(485):. PubMed ID: 28655862
[TBL] [Abstract][Full Text] [Related]
2. Casein Kinase 1α as a Regulator of Wnt-Driven Cancer.
Shen C; Nayak A; Melendez RA; Wynn DT; Jackson J; Lee E; Ahmed Y; Robbins DJ
Int J Mol Sci; 2020 Aug; 21(16):. PubMed ID: 32824859
[TBL] [Abstract][Full Text] [Related]
3. Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α.
Thorne CA; Hanson AJ; Schneider J; Tahinci E; Orton D; Cselenyi CS; Jernigan KK; Meyers KC; Hang BI; Waterson AG; Kim K; Melancon B; Ghidu VP; Sulikowski GA; LaFleur B; Salic A; Lee LA; Miller DM; Lee E
Nat Chem Biol; 2010 Nov; 6(11):829-36. PubMed ID: 20890287
[TBL] [Abstract][Full Text] [Related]
4. Pyrvinium Sensitizes Clear Cell Renal Cell Carcinoma Response to Chemotherapy Via Casein Kinase 1α-Dependent Inhibition of Wnt/β-Catenin.
Cui L; Zhao J; Liu J
Am J Med Sci; 2018 Mar; 355(3):274-280. PubMed ID: 29549930
[TBL] [Abstract][Full Text] [Related]
5. A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma.
Rodriguez-Blanco J; Li B; Long J; Shen C; Yang F; Orton D; Collins S; Kasahara N; Ayad NG; McCrea HJ; Roussel MF; Weiss WA; Capobianco AJ; Robbins DJ
Clin Cancer Res; 2019 Feb; 25(4):1379-1388. PubMed ID: 30487124
[TBL] [Abstract][Full Text] [Related]
6. The CK1α Activator Pyrvinium Enhances the Catalytic Efficiency (
Shen C; Li B; Astudillo L; Deutscher MP; Cobb MH; Capobianco AJ; Lee E; Robbins DJ
Biochemistry; 2019 Dec; 58(51):5102-5106. PubMed ID: 31820934
[TBL] [Abstract][Full Text] [Related]
7. The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon.
Shen C; Nayak A; Neitzel LR; Yang F; Li B; Williams CH; Hong CC; Ahmed Y; Lee E; Robbins DJ
J Biol Chem; 2022 Aug; 298(8):102227. PubMed ID: 35780831
[TBL] [Abstract][Full Text] [Related]
8. Ricinine: a pyridone alkaloid from Ricinus communis that activates the Wnt signaling pathway through casein kinase 1α.
Ohishi K; Toume K; Arai MA; Sadhu SK; Ahmed F; Mizoguchi T; Itoh M; Ishibashi M
Bioorg Med Chem; 2014 Sep; 22(17):4597-601. PubMed ID: 25124862
[TBL] [Abstract][Full Text] [Related]
9. Repurposing the FDA-approved pinworm drug pyrvinium as a novel chemotherapeutic agent for intestinal polyposis.
Li B; Flaveny CA; Giambelli C; Fei DL; Han L; Hang BI; Bai F; Pei XH; Nose V; Burlingame O; Capobianco AJ; Orton D; Lee E; Robbins DJ
PLoS One; 2014; 9(7):e101969. PubMed ID: 25003333
[TBL] [Abstract][Full Text] [Related]
10. Pyrvinium doubles against WNT-driven cancer.
Fan J; Reid RR; He TC
J Biol Chem; 2022 Oct; 298(10):102479. PubMed ID: 36096200
[TBL] [Abstract][Full Text] [Related]
11. Pyrvinium, a potent small molecule Wnt inhibitor, promotes wound repair and post-MI cardiac remodeling.
Saraswati S; Alfaro MP; Thorne CA; Atkinson J; Lee E; Young PP
PLoS One; 2010 Nov; 5(11):e15521. PubMed ID: 21170416
[TBL] [Abstract][Full Text] [Related]
12. Pyrvinium attenuates Hedgehog signaling downstream of smoothened.
Li B; Fei DL; Flaveny CA; Dahmane N; Baubet V; Wang Z; Bai F; Pei XH; Rodriguez-Blanco J; Hang B; Orton D; Han L; Wang B; Capobianco AJ; Lee E; Robbins DJ
Cancer Res; 2014 Sep; 74(17):4811-21. PubMed ID: 24994715
[TBL] [Abstract][Full Text] [Related]
13. MDMX inhibits casein kinase 1α activity and stimulates Wnt signaling.
Huang Q; Chen L; Schonbrunn E; Chen J
EMBO J; 2020 Jul; 39(14):e104410. PubMed ID: 32511789
[TBL] [Abstract][Full Text] [Related]
14. Calotropin: a cardenolide from calotropis gigantea that inhibits Wnt signaling by increasing casein kinase 1α in colon cancer cells.
Park HY; Toume K; Arai MA; Sadhu SK; Ahmed F; Ishibashi M
Chembiochem; 2014 Apr; 15(6):872-8. PubMed ID: 24644251
[TBL] [Abstract][Full Text] [Related]
15. Targeting the CK1α/CBX4 axis for metastasis in osteosarcoma.
Wang X; Qin G; Liang X; Wang W; Wang Z; Liao D; Zhong L; Zhang R; Zeng YX; Wu Y; Kang T
Nat Commun; 2020 Feb; 11(1):1141. PubMed ID: 32111827
[TBL] [Abstract][Full Text] [Related]
16. FAM83F regulates canonical Wnt signalling through an interaction with CK1α.
Dunbar K; Jones RA; Dingwell K; Macartney TJ; Smith JC; Sapkota GP
Life Sci Alliance; 2021 Feb; 4(2):. PubMed ID: 33361109
[TBL] [Abstract][Full Text] [Related]
17. CK1α suppresses lung tumour growth by stabilizing PTEN and inducing autophagy.
Cai J; Li R; Xu X; Zhang L; Lian R; Fang L; Huang Y; Feng X; Liu X; Li X; Zhu X; Zhang H; Wu J; Zeng M; Song E; He Y; Yin Y; Li J; Li M
Nat Cell Biol; 2018 Apr; 20(4):465-478. PubMed ID: 29593330
[TBL] [Abstract][Full Text] [Related]
18. Suppression of casein kinase 1alpha in melanoma cells induces a switch in beta-catenin signaling to promote metastasis.
Sinnberg T; Menzel M; Kaesler S; Biedermann T; Sauer B; Nahnsen S; Schwarz M; Garbe C; Schittek B
Cancer Res; 2010 Sep; 70(17):6999-7009. PubMed ID: 20699366
[TBL] [Abstract][Full Text] [Related]
19. Casein kinase 1α-dependent inhibition of Wnt/β-catenin selectively targets nasopharyngeal carcinoma and increases chemosensitivity.
Li J; Jiang Y; Wang P; Ke S; Yang L; Shen Y
Anticancer Drugs; 2019 Aug; 30(7):e0747. PubMed ID: 31305293
[TBL] [Abstract][Full Text] [Related]
20. Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling.
Kong LM; Feng T; Wang YY; Li XY; Ye ZN; An T; Qing C; Luo XD; Li Y
Oncotarget; 2016 Mar; 7(9):10203-14. PubMed ID: 26862734
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
