398 related articles for article (PubMed ID: 28656524)
1. Identification of potential trypanothione reductase inhibitors among commercially available β-carboline derivatives using chemical space, lead-like and drug-like filters, pharmacophore models and molecular docking.
Rodríguez-Becerra J; Cáceres-Jensen L; Hernández-Ramos J; Barrientos L
Mol Divers; 2017 Aug; 21(3):697-711. PubMed ID: 28656524
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors.
Bond CS; Zhang Y; Berriman M; Cunningham ML; Fairlamb AH; Hunter WN
Structure; 1999 Jan; 7(1):81-9. PubMed ID: 10368274
[TBL] [Abstract][Full Text] [Related]
3. Structural analysis and molecular docking of trypanocidal aryloxy-quinones in trypanothione and glutathione reductases: a comparison with biochemical data.
Vera B; Vázquez K; Mascayano C; Tapia RA; Espinosa V; Soto-Delgado J; Salas CO; Paulino M
J Biomol Struct Dyn; 2017 Jun; 35(8):1785-1803. PubMed ID: 27232454
[TBL] [Abstract][Full Text] [Related]
4. Trypanothione reductase: a target protein for a combined in vitro and in silico screening approach.
Beig M; Oellien F; Garoff L; Noack S; Krauth-Siegel RL; Selzer PM
PLoS Negl Trop Dis; 2015; 9(6):e0003773. PubMed ID: 26042772
[TBL] [Abstract][Full Text] [Related]
5. Trypanothione Reductase and Superoxide Dismutase as Current Drug Targets for Trypanosoma cruzi: An Overview of Compounds with Activity against Chagas Disease.
Beltran-Hortelano I; Perez-Silanes S; Galiano S
Curr Med Chem; 2017 May; 24(11):1066-1138. PubMed ID: 28025938
[TBL] [Abstract][Full Text] [Related]
6. Trypanothione Reductase: A Target for the Development of Anti- Trypanosoma cruzi Drugs.
Vázquez K; Paulino M; Salas CO; Zarate-Ramos JJ; Vera B; Rivera G
Mini Rev Med Chem; 2017; 17(11):939-946. PubMed ID: 28302040
[TBL] [Abstract][Full Text] [Related]
7. Molecular docking of a series of peptidomimetics in the trypanothione binding site of T. cruzi trypanothione reductase.
da Rocha Pita SS; Cirino JJ; de Alencastro RB; Castro HC; Rodrigues CR; Albuquerque MG
J Mol Graph Model; 2009 Nov; 28(4):330-5. PubMed ID: 19766515
[TBL] [Abstract][Full Text] [Related]
8. Rational design of nitrofuran derivatives: Synthesis and valuation as inhibitors of Trypanosoma cruzi trypanothione reductase.
Arias DG; Herrera FE; Garay AS; Rodrigues D; Forastieri PS; Luna LE; Bürgi MD; Prieto C; Iglesias AA; Cravero RM; Guerrero SA
Eur J Med Chem; 2017 Jan; 125():1088-1097. PubMed ID: 27810595
[TBL] [Abstract][Full Text] [Related]
9. The synthesis and inhibitory activity of dethiotrypanothione and analogues against trypanothione reductase.
Czechowicz JA; Wilhelm AK; Spalding MD; Larson AM; Engel LK; Alberg DG
J Org Chem; 2007 May; 72(10):3689-93. PubMed ID: 17439174
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and evaluation of substrate analogue inhibitors of trypanothione reductase.
Duyzend MH; Clark CT; Simmons SL; Johnson WB; Larson AM; Leconte AM; Wills AW; Ginder-Vogel M; Wilhelm AK; Czechowicz JA; Alberg DG
J Enzyme Inhib Med Chem; 2012 Dec; 27(6):784-94. PubMed ID: 22085139
[TBL] [Abstract][Full Text] [Related]
11. Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.
Chan C; Yin H; Garforth J; McKie JH; Jaouhari R; Speers P; Douglas KT; Rock PJ; Yardley V; Croft SL; Fairlamb AH
J Med Chem; 1998 Jan; 41(2):148-56. PubMed ID: 9457238
[TBL] [Abstract][Full Text] [Related]
12. Molecular dynamics simulations of peptide inhibitors complexed with Trypanosoma cruzi trypanothione reductase.
Silva Da Rocha Pita S; Batista PR; Albuquerque MG; Pascutti PG
Chem Biol Drug Des; 2012 Oct; 80(4):561-71. PubMed ID: 22702225
[TBL] [Abstract][Full Text] [Related]
13. Inhibiting effects of spermidine derivatives on Trypanosoma cruzi trypanothione reductase.
O'Sullivan MC; Dalrymple DM; Zhou Q
J Enzyme Inhib; 1996 Oct; 11(2):97-114. PubMed ID: 9204399
[TBL] [Abstract][Full Text] [Related]
14. Polyamine derivatives as inhibitors of trypanothione reductase and assessment of their trypanocidal activities.
O'Sullivan MC; Zhou Q; Li Z; Durham TB; Rattendi D; Lane S; Bacchi CJ
Bioorg Med Chem; 1997 Dec; 5(12):2145-55. PubMed ID: 9459012
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione binding site of trypanothione reductase as target for rational design.
Aguirre G; Cabrera E; Cerecetto H; Di Maio R; González M; Seoane G; Duffaut A; Denicola A; Gil MJ; Martínez-Merino V
Eur J Med Chem; 2004 May; 39(5):421-31. PubMed ID: 15110968
[TBL] [Abstract][Full Text] [Related]
16. Trypanocidal Activity of Quinoxaline 1,4 Di-N-oxide Derivatives as Trypanothione Reductase Inhibitors.
Chacón-Vargas KF; Nogueda-Torres B; Sánchez-Torres LE; Suarez-Contreras E; Villalobos-Rocha JC; Torres-Martinez Y; Lara-Ramirez EE; Fiorani G; Krauth-Siegel RL; Bolognesi ML; Monge A; Rivera G
Molecules; 2017 Feb; 22(2):. PubMed ID: 28157150
[TBL] [Abstract][Full Text] [Related]
17. 2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity.
Salmon-Chemin L; Buisine E; Yardley V; Kohler S; Debreu MA; Landry V; Sergheraert C; Croft SL; Krauth-Siegel RL; Davioud-Charvet E
J Med Chem; 2001 Feb; 44(4):548-65. PubMed ID: 11170645
[TBL] [Abstract][Full Text] [Related]
18. Structure-activity relationships in 2-aminodiphenylsulfides against trypanothione reductase from Trypanosoma cruzi.
Girault S; Davioud-Charvet E; Salmon L; Berecibar A; Debreu MA; Sergheraert C
Bioorg Med Chem Lett; 1998 May; 8(10):1175-80. PubMed ID: 9871730
[TBL] [Abstract][Full Text] [Related]
19. Dibenzosuberyl substituted polyamines and analogs of clomipramine as effective inhibitors of trypanothione reductase; molecular docking, and assessment of trypanocidal activities.
O'Sullivan MC; Durham TB; Valdes HE; Dauer KL; Karney NJ; Forrestel AC; Bacchi CJ; Baker JF
Bioorg Med Chem; 2015 Mar; 23(5):996-1010. PubMed ID: 25661449
[TBL] [Abstract][Full Text] [Related]
20. Nitrofuran drugs as common subversive substrates of Trypanosoma cruzi lipoamide dehydrogenase and trypanothione reductase.
Blumenstiel K; Schöneck R; Yardley V; Croft SL; Krauth-Siegel RL
Biochem Pharmacol; 1999 Dec; 58(11):1791-9. PubMed ID: 10571254
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
