254 related articles for article (PubMed ID: 28659580)
21. Amyloid β-protein oligomers upregulate the β-secretase, BACE1, through a post-translational mechanism involving its altered subcellular distribution in neurons.
Mamada N; Tanokashira D; Hosaka A; Kametani F; Tamaoka A; Araki W
Mol Brain; 2015 Nov; 8(1):73. PubMed ID: 26552445
[TBL] [Abstract][Full Text] [Related]
22. Memantine reduces the production of amyloid-β peptides through modulation of amyloid precursor protein trafficking.
Ito K; Tatebe T; Suzuki K; Hirayama T; Hayakawa M; Kubo H; Tomita T; Makino M
Eur J Pharmacol; 2017 Mar; 798():16-25. PubMed ID: 28167259
[TBL] [Abstract][Full Text] [Related]
23. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
24. Leptin attenuates BACE1 expression and amyloid-β genesis via the activation of SIRT1 signaling pathway.
Marwarha G; Raza S; Meiers C; Ghribi O
Biochim Biophys Acta; 2014 Sep; 1842(9):1587-95. PubMed ID: 24874077
[TBL] [Abstract][Full Text] [Related]
25. Ginsenoside Rg1 attenuates β-amyloid generation via suppressing PPARγ-regulated BACE1 activity in N2a-APP695 cells.
Chen LM; Lin ZY; Zhu YG; Lin N; Zhang J; Pan XD; Chen XC
Eur J Pharmacol; 2012 Jan; 675(1-3):15-21. PubMed ID: 22166376
[TBL] [Abstract][Full Text] [Related]
26. A specific RAGE-binding peptide biopanning from phage display random peptide library that ameliorates symptoms in amyloid β peptide-mediated neuronal disorder.
Cai C; Dai X; Zhu Y; Lian M; Xiao F; Dong F; Zhang Q; Huang Y; Zheng Q
Appl Microbiol Biotechnol; 2016 Jan; 100(2):825-35. PubMed ID: 26496918
[TBL] [Abstract][Full Text] [Related]
27. Glimepiride attenuates Aβ production via suppressing BACE1 activity in cortical neurons.
Liu F; Wang Y; Yan M; Zhang L; Pang T; Liao H
Neurosci Lett; 2013 Dec; 557 Pt B():90-4. PubMed ID: 24184877
[TBL] [Abstract][Full Text] [Related]
28. BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice.
Kim W; Ma L; Lomoio S; Willen R; Lombardo S; Dong J; Haydon PG; Tesco G
Mol Neurodegener; 2018 Feb; 13(1):6. PubMed ID: 29391027
[TBL] [Abstract][Full Text] [Related]
29. Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
Li S; Hou H; Mori T; Sawmiller D; Smith A; Tian J; Wang Y; Giunta B; Sanberg PR; Zhang S; Tan J
Sci Rep; 2015 Jun; 5():11322. PubMed ID: 26091071
[TBL] [Abstract][Full Text] [Related]
30. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
Wu G; Sankaranarayanan S; Hsieh SH; Simon AJ; Savage MJ
J Neurosci Res; 2011 Jun; 89(6):822-32. PubMed ID: 21433051
[TBL] [Abstract][Full Text] [Related]
31. Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer's disease.
Andrew RJ; Fernandez CG; Stanley M; Jiang H; Nguyen P; Rice RC; Buggia-Prévot V; De Rossi P; Vetrivel KS; Lamb R; Argemi A; Allaert ES; Rathbun EM; Krause SV; Wagner SL; Parent AT; Holtzman DM; Thinakaran G
Proc Natl Acad Sci U S A; 2017 Nov; 114(45):E9665-E9674. PubMed ID: 29078331
[TBL] [Abstract][Full Text] [Related]
32. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.
Ho L; Qin W; Pompl PN; Xiang Z; Wang J; Zhao Z; Peng Y; Cambareri G; Rocher A; Mobbs CV; Hof PR; Pasinetti GM
FASEB J; 2004 May; 18(7):902-4. PubMed ID: 15033922
[TBL] [Abstract][Full Text] [Related]
33. Metformin increases APP expression and processing via oxidative stress, mitochondrial dysfunction and NF-κB activation: Use of insulin to attenuate metformin's effect.
Picone P; Nuzzo D; Caruana L; Messina E; Barera A; Vasto S; Di Carlo M
Biochim Biophys Acta; 2015 May; 1853(5):1046-59. PubMed ID: 25667085
[TBL] [Abstract][Full Text] [Related]
34. The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha.
Guglielmotto M; Aragno M; Autelli R; Giliberto L; Novo E; Colombatto S; Danni O; Parola M; Smith MA; Perry G; Tamagno E; Tabaton M
J Neurochem; 2009 Feb; 108(4):1045-56. PubMed ID: 19196431
[TBL] [Abstract][Full Text] [Related]
35. A GPCR/secretase complex regulates beta- and gamma-secretase specificity for Abeta production and contributes to AD pathogenesis.
Teng L; Zhao J; Wang F; Ma L; Pei G
Cell Res; 2010 Feb; 20(2):138-53. PubMed ID: 20066010
[TBL] [Abstract][Full Text] [Related]
36. Melatonin regulates the transcription of βAPP-cleaving secretases mediated through melatonin receptors in human neuroblastoma SH-SY5Y cells.
Panmanee J; Nopparat C; Chavanich N; Shukla M; Mukda S; Song W; Vincent B; Govitrapong P
J Pineal Res; 2015 Oct; 59(3):308-20. PubMed ID: 26123100
[TBL] [Abstract][Full Text] [Related]
37. Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.
Marwarha G; Rostad S; Lilek J; Kleinjan M; Schommer J; Ghribi O
J Alzheimers Dis; 2017; 57(3):907-925. PubMed ID: 28304295
[TBL] [Abstract][Full Text] [Related]
38. The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling.
Botteri G; Salvadó L; Gumà A; Lee Hamilton D; Meakin PJ; Montagut G; Ashford MLJ; Ceperuelo-Mallafré V; Fernández-Veledo S; Vendrell J; Calderón-Dominguez M; Serra D; Herrero L; Pizarro J; Barroso E; Palomer X; Vázquez-Carrera M
Metabolism; 2018 Aug; 85():59-75. PubMed ID: 29526536
[TBL] [Abstract][Full Text] [Related]
39. Sphingosylphosphorylcholine attenuated β-amyloid production by reducing BACE1 expression and catalysis in PC12 cells.
Yi H; Lee SJ; Lee J; Myung CS; Park WK; Lim HJ; Lee GH; Kong JY; Cho H
Neurochem Res; 2011 Nov; 36(11):2083-90. PubMed ID: 21674237
[TBL] [Abstract][Full Text] [Related]
40. Downregulation of PI3K/Akt/mTOR signaling pathway in curcumin-induced autophagy in APP/PS1 double transgenic mice.
Wang C; Zhang X; Teng Z; Zhang T; Li Y
Eur J Pharmacol; 2014 Oct; 740():312-20. PubMed ID: 25041840
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]