These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 28678475)

  • 1. Transition States and Control of Substrate Preference in the Promiscuous Phosphatase PP1.
    Chu Y; Williams NH; Hengge AC
    Biochemistry; 2017 Aug; 56(30):3923-3933. PubMed ID: 28678475
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanistic study of protein phosphatase-1 (PP1), a catalytically promiscuous enzyme.
    McWhirter C; Lund EA; Tanifum EA; Feng G; Sheikh QI; Hengge AC; Williams NH
    J Am Chem Soc; 2008 Oct; 130(41):13673-82. PubMed ID: 18798625
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Site-directed mutagenesis maps interactions that enhance cognate and limit promiscuous catalysis by an alkaline phosphatase superfamily phosphodiesterase.
    Wiersma-Koch H; Sunden F; Herschlag D
    Biochemistry; 2013 Dec; 52(51):9167-76. PubMed ID: 24261692
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutation of Arg-166 of alkaline phosphatase alters the thio effect but not the transition state for phosphoryl transfer. Implications for the interpretation of thio effects in reactions of phosphatases.
    Holtz KM; Catrina IE; Hengge AC; Kantrowitz ER
    Biochemistry; 2000 Aug; 39(31):9451-8. PubMed ID: 10924140
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanistic studies of protein tyrosine phosphatases YopH and Cdc25A with m-nitrobenzyl phosphate.
    McCain DF; Grzyska PK; Wu L; Hengge AC; Zhang ZY
    Biochemistry; 2004 Jun; 43(25):8256-64. PubMed ID: 15209522
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Facilitating the Evolution of Esterase Activity from a Promiscuous Enzyme (Mhg) with Catalytic Functions of Amide Hydrolysis and Carboxylic Acid Perhydrolysis by Engineering the Substrate Entrance Tunnel.
    Yan X; Wang J; Sun Y; Zhu J; Wu S
    Appl Environ Microbiol; 2016 Nov; 82(22):6748-6756. PubMed ID: 27613682
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional interrelationships in the alkaline phosphatase superfamily: phosphodiesterase activity of Escherichia coli alkaline phosphatase.
    O'Brien PJ; Herschlag D
    Biochemistry; 2001 May; 40(19):5691-9. PubMed ID: 11341834
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Formation of Catalytically Active Binuclear Center of Glycerophosphodiesterase: A Molecular Dynamics Study.
    Paul TJ; Schenk G; Prabhakar R
    J Phys Chem B; 2018 Jun; 122(22):5797-5808. PubMed ID: 29723477
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Transition-state structures for the native dual-specific phosphatase VHR and D92N and S131A mutants. Contributions to the driving force for catalysis.
    Hengge AC; Denu JM; Dixon JE
    Biochemistry; 1996 Jun; 35(22):7084-92. PubMed ID: 8679534
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Examining the promiscuous phosphatase activity of Pseudomonas aeruginosa arylsulfatase: a comparison to analogous phosphatases.
    Luo J; van Loo B; Kamerlin SC
    Proteins; 2012 Apr; 80(4):1211-26. PubMed ID: 22275090
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetic and structural evaluation of selected active site mutants of the Aspergillus fumigatus KDNase (sialidase).
    Yeung JH; Telford JC; Shidmoossavee FS; Bennet AJ; Taylor GL; Moore MM
    Biochemistry; 2013 Dec; 52(51):9177-86. PubMed ID: 24295366
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The effect of a unique halide-stabilizing residue on the catalytic properties of haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58.
    Hasan K; Gora A; Brezovsky J; Chaloupkova R; Moskalikova H; Fortova A; Nagata Y; Damborsky J; Prokop Z
    FEBS J; 2013 Jul; 280(13):3149-59. PubMed ID: 23490078
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Substrate-assisted movement of the catalytic Lys 215 during domain closure: site-directed mutagenesis studies of human 3-phosphoglycerate kinase.
    Flachner B; Varga A; Szabó J; Barna L; Hajdú I; Gyimesi G; Závodszky P; Vas M
    Biochemistry; 2005 Dec; 44(51):16853-65. PubMed ID: 16363799
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphate monoester hydrolysis by trinuclear alkaline phosphatase; DFT study of transition States and reaction mechanism.
    Chen SL; Liao RZ
    Chemphyschem; 2014 Aug; 15(11):2321-30. PubMed ID: 24683174
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The nonconserved N-terminus of protein phosphatases 1 influences its active site.
    Xie X; Huang W; Xue C; Wei Q
    BMB Rep; 2008 Dec; 41(12):881-5. PubMed ID: 19123980
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The promiscuous phosphomonoestearase activity of Archaeoglobus fulgidus CopA, a thermophilic Cu+ transport ATPase.
    Bredeston LM; González Flecha FL
    Biochim Biophys Acta; 2016 Jul; 1858(7 Pt A):1471-8. PubMed ID: 27086711
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of a phosphodiesterase capable of hydrolyzing EA 2192, the most toxic degradation product of the nerve agent VX.
    Ghanem E; Li Y; Xu C; Raushel FM
    Biochemistry; 2007 Aug; 46(31):9032-40. PubMed ID: 17630782
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evolutionary repurposing of a sulfatase: A new Michaelis complex leads to efficient transition state charge offset.
    Miton CM; Jonas S; Fischer G; Duarte F; Mohamed MF; van Loo B; Kintses B; Kamerlin SCL; Tokuriki N; Hyvönen M; Hollfelder F
    Proc Natl Acad Sci U S A; 2018 Jul; 115(31):E7293-E7302. PubMed ID: 30012610
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Second-Shell Amino Acid R266 Helps Determine
    Truong DP; Rousseau S; Machala BW; Huddleston JP; Zhu M; Hull KG; Romo D; Raushel FM; Sacchettini JC; Glasner ME
    Biochemistry; 2021 Dec; 60(50):3829-3840. PubMed ID: 34845903
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Efficient catalytic promiscuity in an enzyme superfamily: an arylsulfatase shows a rate acceleration of 10(13) for phosphate monoester hydrolysis.
    Olguin LF; Askew SE; O'Donoghue AC; Hollfelder F
    J Am Chem Soc; 2008 Dec; 130(49):16547-55. PubMed ID: 19554727
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.