These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Heterogeneous multimeric structure of isocitrate lyase in complex with succinate and itaconate provides novel insights into its inhibitory mechanism. Kwon S; Chun HL; Ha HJ; Lee SY; Park HH PLoS One; 2021; 16(5):e0251067. PubMed ID: 33951112 [TBL] [Abstract][Full Text] [Related]
6. Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis. Sharma V; Sharma S; Hoener zu Bentrup K; McKinney JD; Russell DG; Jacobs WR; Sacchettini JC Nat Struct Biol; 2000 Aug; 7(8):663-8. PubMed ID: 10932251 [TBL] [Abstract][Full Text] [Related]
8. Identification of a novel inhibitor of isocitrate lyase as a potent antitubercular agent against both active and non-replicating Mycobacterium tuberculosis. Liu Y; Zhou S; Deng Q; Li X; Meng J; Guan Y; Li C; Xiao C Tuberculosis (Edinb); 2016 Mar; 97():38-46. PubMed ID: 26980494 [TBL] [Abstract][Full Text] [Related]
9. The Nitro Group as a Masked Electrophile in Covalent Enzyme Inhibition. Ray S; Kreitler DF; Gulick AM; Murkin AS ACS Chem Biol; 2018 Jun; 13(6):1470-1473. PubMed ID: 29782144 [TBL] [Abstract][Full Text] [Related]
10. Structure-function insights into elusive Mycobacterium tuberculosis protein Rv1916. Antil M; Sharma J; Brissonnet Y; Choudhary M; Gouin S; Gupta V Int J Biol Macromol; 2019 Dec; 141():927-936. PubMed ID: 31505209 [TBL] [Abstract][Full Text] [Related]
11. Cysteine is the general base that serves in catalysis by isocitrate lyase and in mechanism-based inhibition by 3-nitropropionate. Moynihan MM; Murkin AS Biochemistry; 2014 Jan; 53(1):178-87. PubMed ID: 24354272 [TBL] [Abstract][Full Text] [Related]
12. Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis. Gould TA; van de Langemheen H; Muñoz-Elías EJ; McKinney JD; Sacchettini JC Mol Microbiol; 2006 Aug; 61(4):940-7. PubMed ID: 16879647 [TBL] [Abstract][Full Text] [Related]
13. Potential inhibitors for isocitrate lyase of Mycobacterium tuberculosis and non-M. tuberculosis: a summary. Lee YV; Wahab HA; Choong YS Biomed Res Int; 2015; 2015():895453. PubMed ID: 25649791 [TBL] [Abstract][Full Text] [Related]
14. Active Site Flexibility of Mycobacterium tuberculosis Isocitrate Lyase in Dimer Form. Lee YV; Choi SB; Wahab HA; Choong YS J Chem Inf Model; 2017 Sep; 57(9):2351-2357. PubMed ID: 28820943 [TBL] [Abstract][Full Text] [Related]
15. Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence. Muñoz-Elías EJ; McKinney JD Nat Med; 2005 Jun; 11(6):638-44. PubMed ID: 15895072 [TBL] [Abstract][Full Text] [Related]
19. Regulation of the Ko EM; Kim JY; Lee S; Kim S; Hwang J; Oh JI J Bacteriol; 2021 Nov; 203(23):e0040221. PubMed ID: 34516281 [TBL] [Abstract][Full Text] [Related]
20. Activity loss by H46A mutation in Mycobacterium tuberculosis isocitrate lyase is due to decrease in structural plasticity and collective motions of the active site. Shukla R; Shukla H; Tripathi T Tuberculosis (Edinb); 2018 Jan; 108():143-150. PubMed ID: 29523315 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]