197 related articles for article (PubMed ID: 28682648)
1. Kinase inhibitors of the IGF-1R as a potential therapeutic agent for rheumatoid arthritis.
Tsushima H; Morimoto S; Fujishiro M; Yoshida Y; Hayakawa K; Hirai T; Miyashita T; Ikeda K; Yamaji K; Takamori K; Takasaki Y; Sekigawa I; Tamura N
Autoimmunity; 2017 Aug; 50(5):329-335. PubMed ID: 28682648
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of the insulin-like growth factor system is a potential therapy for rheumatoid arthritis.
Suzuki S; Morimoto S; Fujishiro M; Kawasaki M; Hayakawa K; Miyashita T; Ikeda K; Miyazawa K; Yanagida M; Takamori K; Ogawa H; Sekigawa I; Takasaki Y
Autoimmunity; 2015 Jun; 48(4):251-8. PubMed ID: 25352179
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of each module of connective tissue growth factor as a potential therapeutic target for rheumatoid arthritis.
Miyashita T; Morimoto S; Fujishiro M; Hayakawa K; Suzuki S; Ikeda K; Miyazawa K; Morioka M; Takamori K; Ogawa H; Sekigawa I; Takasaki Y
Autoimmunity; 2016; 49(2):109-14. PubMed ID: 26584911
[TBL] [Abstract][Full Text] [Related]
4. Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas.
Piao W; Wang Y; Adachi Y; Yamamoto H; Li R; Imsumran A; Li H; Maehata T; Ii M; Arimura Y; Lee CT; Shinomura Y; Carbone DP; Imai K
Mol Cancer Ther; 2008 Jun; 7(6):1483-93. PubMed ID: 18566219
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of insulin-like growth factor-I receptor (IGF-IR) using NVP-AEW541, a small molecule kinase inhibitor, reduces orthotopic pancreatic cancer growth and angiogenesis.
Moser C; Schachtschneider P; Lang SA; Gaumann A; Mori A; Zimmermann J; Schlitt HJ; Geissler EK; Stoeltzing O
Eur J Cancer; 2008 Jul; 44(11):1577-86. PubMed ID: 18445520
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of the insulin-like growth factor-1 receptor potentiates acute effects of castration in a rat model for prostate cancer growth in bone.
Nordstrand A; Bergström SH; Thysell E; Bovinder-Ylitalo E; Lerner UH; Widmark A; Bergh A; Wikström P
Clin Exp Metastasis; 2017 Apr; 34(3-4):261-271. PubMed ID: 28447314
[TBL] [Abstract][Full Text] [Related]
7. Th17 cytokines regulate osteoclastogenesis in rheumatoid arthritis.
Kim KW; Kim HR; Kim BM; Cho ML; Lee SH
Am J Pathol; 2015 Nov; 185(11):3011-24. PubMed ID: 26362732
[TBL] [Abstract][Full Text] [Related]
8. Caffeic acid 3,4-dihydroxy-phenethyl ester suppresses receptor activator of NF-κB ligand–induced osteoclastogenesis and prevents ovariectomy-induced bone loss through inhibition of mitogen-activated protein kinase/activator protein 1 and Ca2+–nuclear factor of activated T-cells cytoplasmic 1 signaling pathways.
Wu X; Li Z; Yang Z; Zheng C; Jing J; Chen Y; Ye X; Lian X; Qiu W; Yang F; Tang J; Xiao J; Liu M; Luo J
J Bone Miner Res; 2012 Jun; 27(6):1298-1308. PubMed ID: 22337253
[TBL] [Abstract][Full Text] [Related]
9. Picropodophyllin inhibits proliferation and survival of diffuse large B-cell lymphoma cells.
Strömberg T; Feng X; Delforoush M; Berglund M; Lin Y; Axelson M; Larsson O; Georgii-Hemming P; Lennartsson J; Enblad G
Med Oncol; 2015 Jul; 32(7):188. PubMed ID: 26021470
[TBL] [Abstract][Full Text] [Related]
10. Effects of disease-modifying antirheumatic drugs and antiinflammatory cytokines on human osteoclastogenesis through interaction with receptor activator of nuclear factor kappaB, osteoprotegerin, and receptor activator of nuclear factor kappaB ligand.
Lee CK; Lee EY; Chung SM; Mun SH; Yoo B; Moon HB
Arthritis Rheum; 2004 Dec; 50(12):3831-43. PubMed ID: 15593184
[TBL] [Abstract][Full Text] [Related]
11. TWEAK promotes osteoclastogenesis in rheumatoid arthritis.
Park JS; Kwok SK; Lim MA; Oh HJ; Kim EK; Jhun JY; Ju JH; Park KS; Park YW; Park SH; Kim HY; Cho YG; Cho ML
Am J Pathol; 2013 Sep; 183(3):857-67. PubMed ID: 23845567
[TBL] [Abstract][Full Text] [Related]
12. Dual treatments targeting IGF-1R, PI3K, mTORC or MEK synergize to inhibit cell growth, induce apoptosis, and arrest cell cycle at G1 phase in MDA-MB-231 cell line.
Ayub A; Yip WK; Seow HF
Biomed Pharmacother; 2015 Oct; 75():40-50. PubMed ID: 26463630
[TBL] [Abstract][Full Text] [Related]
13. The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion.
Tazzari PL; Tabellini G; Bortul R; Papa V; Evangelisti C; Grafone T; Martinelli G; McCubrey JA; Martelli AM
Leukemia; 2007 May; 21(5):886-96. PubMed ID: 17361225
[TBL] [Abstract][Full Text] [Related]
14. Down-regulation of insulin-like growth factor I receptor activity by NVP-AEW541 has an antitumor effect on neuroblastoma cells in vitro and in vivo.
Tanno B; Mancini C; Vitali R; Mancuso M; McDowell HP; Dominici C; Raschellà G
Clin Cancer Res; 2006 Nov; 12(22):6772-80. PubMed ID: 17121898
[TBL] [Abstract][Full Text] [Related]
15. Blockade of IGF-1 receptor tyrosine kinase has antineoplastic effects in hepatocellular carcinoma cells.
Höpfner M; Huether A; Sutter AP; Baradari V; Schuppan D; Scherübl H
Biochem Pharmacol; 2006 May; 71(10):1435-48. PubMed ID: 16530734
[TBL] [Abstract][Full Text] [Related]
16. The insulin-like growth factor receptor 1 is a promising target for novel treatment approaches in neuroendocrine gastrointestinal tumours.
Höpfner M; Baradari V; Huether A; Schöfl C; Scherübl H
Endocr Relat Cancer; 2006 Mar; 13(1):135-49. PubMed ID: 16601284
[TBL] [Abstract][Full Text] [Related]
17. Calcium-containing crystals enhance receptor activator of nuclear factor κB ligand/macrophage colony-stimulating factor-mediated osteoclastogenesis via extracellular-signal-regulated kinase and p38 pathways.
Chang CC; Tsai YH; Liu Y; Lin SY; Liang YC
Rheumatology (Oxford); 2015 Oct; 54(10):1913-22. PubMed ID: 25998451
[TBL] [Abstract][Full Text] [Related]
18. Connective tissue growth factor promotes articular damage by increased osteoclastogenesis in patients with rheumatoid arthritis.
Nozawa K; Fujishiro M; Kawasaki M; Kaneko H; Iwabuchi K; Yanagida M; Suzuki F; Miyazawa K; Takasaki Y; Ogawa H; Takamori K; Sekigawa I
Arthritis Res Ther; 2009; 11(6):R174. PubMed ID: 19922639
[TBL] [Abstract][Full Text] [Related]
19. Co-Targeting IGF-1R and Autophagy Enhances the Effects of Cell Growth Suppression and Apoptosis Induced by the IGF-1R Inhibitor NVP-AEW541 in Triple-Negative Breast Cancer Cells.
Wu W; Ma J; Shao N; Shi Y; Liu R; Li W; Lin Y; Wang S
PLoS One; 2017; 12(1):e0169229. PubMed ID: 28046018
[TBL] [Abstract][Full Text] [Related]
20. The insulin-like growth factor-I receptor inhibitor NVP-AEW541 provokes cell cycle arrest and apoptosis in multiple myeloma cells.
Maiso P; Ocio EM; Garayoa M; Montero JC; Hofmann F; García-Echeverría C; Zimmermann J; Pandiella A; San Miguel JF
Br J Haematol; 2008 May; 141(4):470-82. PubMed ID: 18341634
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]