BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 28686577)

  • 1. mTOR/Raptor signaling is critical for skeletogenesis in mice through the regulation of Runx2 expression.
    Dai Q; Xu Z; Ma X; Niu N; Zhou S; Xie F; Jiang L; Wang J; Zou W
    Cell Death Differ; 2017 Nov; 24(11):1886-1899. PubMed ID: 28686577
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivation of Regulatory-associated Protein of mTOR (Raptor)/Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling in Osteoclasts Increases Bone Mass by Inhibiting Osteoclast Differentiation in Mice.
    Dai Q; Xie F; Han Y; Ma X; Zhou S; Jiang L; Zou W; Wang J
    J Biol Chem; 2017 Jan; 292(1):196-204. PubMed ID: 27879318
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conditional Disruption of Raptor Reveals an Essential Role for mTORC1 in B Cell Development, Survival, and Metabolism.
    Iwata TN; Ramírez JA; Tsang M; Park H; Margineantu DH; Hockenbery DM; Iritani BM
    J Immunol; 2016 Sep; 197(6):2250-60. PubMed ID: 27521345
    [TBL] [Abstract][Full Text] [Related]  

  • 4. mTORC1 Signaling Promotes Osteoblast Differentiation from Preosteoblasts.
    Chen J; Long F
    PLoS One; 2015; 10(6):e0130627. PubMed ID: 26090674
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cbfβ deletion in mice recapitulates cleidocranial dysplasia and reveals multiple functions of Cbfβ required for skeletal development.
    Chen W; Ma J; Zhu G; Jules J; Wu M; McConnell M; Tian F; Paulson C; Zhou X; Wang L; Li YP
    Proc Natl Acad Sci U S A; 2014 Jun; 111(23):8482-7. PubMed ID: 24850862
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dlx5 and mef2 regulate a novel runx2 enhancer for osteoblast-specific expression.
    Kawane T; Komori H; Liu W; Moriishi T; Miyazaki T; Mori M; Matsuo Y; Takada Y; Izumi S; Jiang Q; Nishimura R; Kawai Y; Komori T
    J Bone Miner Res; 2014 Sep; 29(9):1960-9. PubMed ID: 24692107
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of miR338 rescues cleidocranial dysplasia in Runx2 mutant mice partially via the Hif1a-Vegfa axis.
    Jin R; Zhang H; Lin C; Guo J; Zou W; Chen Z; Liu H
    Exp Mol Med; 2023 Jan; 55(1):69-80. PubMed ID: 36599929
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutant Runx2 regulates amelogenesis and osteogenesis through a miR-185-5p-Dlx2 axis.
    Chang H; Wang Y; Liu H; Nan X; Wong S; Peng S; Gu Y; Zhao H; Feng H
    Cell Death Dis; 2017 Dec; 8(12):3221. PubMed ID: 29242628
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Regulation of bone formation by baicalein via the mTORC1 pathway.
    Li SF; Tang JJ; Chen J; Zhang P; Wang T; Chen TY; Yan B; Huang B; Wang L; Huang MJ; Zhang ZM; Jin DD
    Drug Des Devel Ther; 2015; 9():5169-83. PubMed ID: 26392752
    [TBL] [Abstract][Full Text] [Related]  

  • 10. mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation.
    Fitter S; Matthews MP; Martin SK; Xie J; Ooi SS; Walkley CR; Codrington JD; Ruegg MA; Hall MN; Proud CG; Gronthos S; Zannettino ACW
    Mol Cell Biol; 2017 Apr; 37(7):. PubMed ID: 28069737
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RUNX2 Regulates Osteoblast Differentiation via the BMP4 Signaling Pathway.
    Liu DD; Zhang CY; Liu Y; Li J; Wang YX; Zheng SG
    J Dent Res; 2022 Sep; 101(10):1227-1237. PubMed ID: 35619284
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia.
    Funato N; Nakamura M; Richardson JA; Srivastava D; Yanagisawa H
    Hum Mol Genet; 2015 Jan; 24(2):424-35. PubMed ID: 25209980
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pin1-mediated Runx2 modification is critical for skeletal development.
    Yoon WJ; Islam R; Cho YD; Woo KM; Baek JH; Uchida T; Komori T; van Wijnen A; Stein JL; Lian JB; Stein GS; Choi JY; Bae SC; Ryoo HM
    J Cell Physiol; 2013 Dec; 228(12):2377-85. PubMed ID: 23702614
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Polycystin-1 regulates skeletogenesis through stimulation of the osteoblast-specific transcription factor RUNX2-II.
    Xiao Z; Zhang S; Magenheimer BS; Luo J; Quarles LD
    J Biol Chem; 2008 May; 283(18):12624-34. PubMed ID: 18321855
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice.
    Greenblatt MB; Shim JH; Zou W; Sitara D; Schweitzer M; Hu D; Lotinun S; Sano Y; Baron R; Park JM; Arthur S; Xie M; Schneider MD; Zhai B; Gygi S; Davis R; Glimcher LH
    J Clin Invest; 2010 Jul; 120(7):2457-73. PubMed ID: 20551513
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sulfuretin promotes osteoblastic differentiation in primary cultured osteoblasts and in vivo bone healing.
    Auh QS; Park KR; Yun HM; Lim HC; Kim GH; Lee DS; Kim YC; Oh H; Kim EC
    Oncotarget; 2016 Nov; 7(48):78320-78330. PubMed ID: 27713171
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sphenoid bone hypoplasia is a skeletal phenotype of cleidocranial dysplasia in a mouse model and patients.
    Mitomo K; Matsunaga S; Kitamura K; Nakamura T; Saito A; Komori T; Muramatsu T; Yamaguchi A
    Bone; 2019 Mar; 120():176-186. PubMed ID: 30391578
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway.
    Lee KW; Yook JY; Son MY; Kim MJ; Koo DB; Han YM; Cho YS
    Stem Cells Dev; 2010 Apr; 19(4):557-68. PubMed ID: 19642865
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Runx2 threshold for the cleidocranial dysplasia phenotype.
    Lou Y; Javed A; Hussain S; Colby J; Frederick D; Pratap J; Xie R; Gaur T; van Wijnen AJ; Jones SN; Stein GS; Lian JB; Stein JL
    Hum Mol Genet; 2009 Feb; 18(3):556-68. PubMed ID: 19028669
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of Proliferation, Differentiation and Functions of Osteoblasts by Runx2.
    Komori T
    Int J Mol Sci; 2019 Apr; 20(7):. PubMed ID: 30987410
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.