These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

431 related articles for article (PubMed ID: 28687604)

  • 21. Toward therapeutic targets for SCA3: Insight into the role of Machado-Joseph disease protein ataxin-3 in misfolded proteins clearance.
    Li X; Liu H; Fischhaber PL; Tang TS
    Prog Neurobiol; 2015 Sep; 132():34-58. PubMed ID: 26123252
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A mutant ataxin-3 fragment results from processing at a site N-terminal to amino acid 190 in brain of Machado-Joseph disease-like transgenic mice.
    Colomer Gould VF; Goti D; Pearce D; Gonzalez GA; Gao H; Bermudez de Leon M; Jenkins NA; Copeland NG; Ross CA; Brown DR
    Neurobiol Dis; 2007 Sep; 27(3):362-9. PubMed ID: 17632007
    [TBL] [Abstract][Full Text] [Related]  

  • 23. A mutant ataxin-3 putative-cleavage fragment in brains of Machado-Joseph disease patients and transgenic mice is cytotoxic above a critical concentration.
    Goti D; Katzen SM; Mez J; Kurtis N; Kiluk J; Ben-Haïem L; Jenkins NA; Copeland NG; Kakizuka A; Sharp AH; Ross CA; Mouton PR; Colomer V
    J Neurosci; 2004 Nov; 24(45):10266-79. PubMed ID: 15537899
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Compromised mitochondrial complex II in models of Machado-Joseph disease.
    Laço MN; Oliveira CR; Paulson HL; Rego AC
    Biochim Biophys Acta; 2012 Feb; 1822(2):139-49. PubMed ID: 22037589
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Fibroblasts of Machado Joseph Disease patients reveal autophagy impairment.
    Onofre I; Mendonça N; Lopes S; Nobre R; de Melo JB; Carreira IM; Januário C; Gonçalves AF; de Almeida LP
    Sci Rep; 2016 Jun; 6():28220. PubMed ID: 27328712
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Deregulation of autophagy in postmortem brains of Machado-Joseph disease patients.
    Sittler A; Muriel MP; Marinello M; Brice A; den Dunnen W; Alves S
    Neuropathology; 2018 Apr; 38(2):113-124. PubMed ID: 29218765
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado-Joseph disease.
    Nascimento-Ferreira I; Santos-Ferreira T; Sousa-Ferreira L; Auregan G; Onofre I; Alves S; Dufour N; Colomer Gould VF; Koeppen A; Déglon N; Pereira de Almeida L
    Brain; 2011 May; 134(Pt 5):1400-15. PubMed ID: 21478185
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Machado-Joseph Disease: A Stress Combating Deubiquitylating Enzyme Changing Sides.
    Dantuma NP; Herzog LK
    Adv Exp Med Biol; 2020; 1233():237-260. PubMed ID: 32274760
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Motor uncoordination and neuropathology in a transgenic mouse model of Machado-Joseph disease lacking intranuclear inclusions and ataxin-3 cleavage products.
    Silva-Fernandes A; Costa Mdo C; Duarte-Silva S; Oliveira P; Botelho CM; Martins L; Mariz JA; Ferreira T; Ribeiro F; Correia-Neves M; Costa C; Maciel P
    Neurobiol Dis; 2010 Oct; 40(1):163-76. PubMed ID: 20510362
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Molecular Mechanisms and Cellular Pathways Implicated in Machado-Joseph Disease Pathogenesis.
    Nóbrega C; Simões AT; Duarte-Neves J; Duarte S; Vasconcelos-Ferreira A; Cunha-Santos J; Pereira D; Santana M; Cavadas C; de Almeida LP
    Adv Exp Med Biol; 2018; 1049():349-367. PubMed ID: 29427113
    [TBL] [Abstract][Full Text] [Related]  

  • 31. KPNB1 modulates the Machado-Joseph disease protein ataxin-3 through activation of the mitochondrial protease CLPP.
    Abeditashi M; Weber JJ; Pereira Sena P; Velic A; Kalimeri M; Incebacak Eltemur RD; Schmidt J; Hübener-Schmid J; Hauser S; Macek B; Riess O; Schmidt T
    Cell Mol Life Sci; 2022 Jul; 79(8):401. PubMed ID: 35794401
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Flow cytometry allows rapid detection of protein aggregates in cellular and zebrafish models of spinocerebellar ataxia 3.
    Robinson KJ; Tym MC; Hogan A; Watchon M; Yuan KC; Plenderleith SK; Don EK; Laird AS
    Dis Model Mech; 2021 Oct; 14(10):. PubMed ID: 34473252
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Silencing ataxin-3 mitigates degeneration in a rat model of Machado-Joseph disease: no role for wild-type ataxin-3?
    Alves S; Nascimento-Ferreira I; Dufour N; Hassig R; Auregan G; Nóbrega C; Brouillet E; Hantraye P; Pedroso de Lima MC; Déglon N; de Almeida LP
    Hum Mol Genet; 2010 Jun; 19(12):2380-94. PubMed ID: 20308049
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Caloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway.
    Cunha-Santos J; Duarte-Neves J; Carmona V; Guarente L; Pereira de Almeida L; Cavadas C
    Nat Commun; 2016 May; 7():11445. PubMed ID: 27165717
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease.
    Koch P; Breuer P; Peitz M; Jungverdorben J; Kesavan J; Poppe D; Doerr J; Ladewig J; Mertens J; Tüting T; Hoffmann P; Klockgether T; Evert BO; Wüllner U; Brüstle O
    Nature; 2011 Nov; 480(7378):543-6. PubMed ID: 22113611
    [TBL] [Abstract][Full Text] [Related]  

  • 36. n-Butylidenephthalide exhibits protection against neurotoxicity through regulation of tryptophan 2, 3 dioxygenase in spinocerebellar ataxia type 3.
    Rajamani K; Liu JW; Wu CH; Chiang IT; You DH; Lin SY; Hsieh DK; Lin SZ; Harn HJ; Chiou TW
    Neuropharmacology; 2017 May; 117():434-446. PubMed ID: 28223212
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD.
    Switonski PM; Szlachcic WJ; Krzyzosiak WJ; Figiel M
    Neurobiol Dis; 2015 Jan; 73():174-88. PubMed ID: 25301414
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Combined therapy with m-TOR-dependent and -independent autophagy inducers causes neurotoxicity in a mouse model of Machado-Joseph disease.
    Duarte-Silva S; Silva-Fernandes A; Neves-Carvalho A; Soares-Cunha C; Teixeira-Castro A; Maciel P
    Neuroscience; 2016 Jan; 313():162-73. PubMed ID: 26601773
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice.
    Nóbrega C; Nascimento-Ferreira I; Onofre I; Albuquerque D; Hirai H; Déglon N; de Almeida LP
    PLoS One; 2013; 8(1):e52396. PubMed ID: 23349684
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A Novel Calpain Inhibitor Compound Has Protective Effects on a Zebrafish Model of Spinocerebellar Ataxia Type 3.
    Robinson KJ; Yuan K; Plenderleith SK; Watchon M; Laird AS
    Cells; 2021 Sep; 10(10):. PubMed ID: 34685571
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 22.