BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

277 related articles for article (PubMed ID: 28687610)

  • 1. Regulator of G-protein signaling Gβ5-R7 is a crucial activator of muscarinic M3 receptor-stimulated insulin secretion.
    Wang Q; Pronin AN; Levay K; Almaca J; Fornoni A; Caicedo A; Slepak VZ
    FASEB J; 2017 Nov; 31(11):4734-4744. PubMed ID: 28687610
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The regulatory G protein signaling complex, Gβ5-R7, promotes glucose- and extracellular signal-stimulated insulin secretion.
    Wang Q; Henry TAN; Pronin AN; Jang GF; Lubaczeuski C; Crabb JW; Bernal-Mizrachi E; Slepak VZ
    J Biol Chem; 2020 May; 295(21):7213-7223. PubMed ID: 32229584
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential effects of the Gβ5-RGS7 complex on muscarinic M3 receptor-induced Ca2+ influx and release.
    Karpinsky-Semper D; Volmar CH; Brothers SP; Slepak VZ
    Mol Pharmacol; 2014 May; 85(5):758-68. PubMed ID: 24586057
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Gbeta5-RGS7 complex selectively inhibits muscarinic M3 receptor signaling via the interaction between the third intracellular loop of the receptor and the DEP domain of RGS7.
    Sandiford SL; Slepak VZ
    Biochemistry; 2009 Mar; 48(10):2282-9. PubMed ID: 19182865
    [TBL] [Abstract][Full Text] [Related]  

  • 5. RGS4 is a negative regulator of insulin release from pancreatic beta-cells in vitro and in vivo.
    Ruiz de Azua I; Scarselli M; Rosemond E; Gautam D; Jou W; Gavrilova O; Ebert PJ; Levitt P; Wess J
    Proc Natl Acad Sci U S A; 2010 Apr; 107(17):7999-8004. PubMed ID: 20385802
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Helix 8 and the i3 loop of the muscarinic M3 receptor are crucial sites for its regulation by the Gβ5-RGS7 complex.
    Karpinsky-Semper D; Tayou J; Levay K; Schuchardt BJ; Bhat V; Volmar CH; Farooq A; Slepak VZ
    Biochemistry; 2015 Feb; 54(4):1077-88. PubMed ID: 25551629
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biochemical purification and functional analysis of complexes between the G-protein subunit Gbeta5 and RGS proteins.
    Witherow DS; Slepak VZ
    Methods Enzymol; 2004; 390():149-62. PubMed ID: 15488176
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Muscarinic control of MIN6 pancreatic β cells is enhanced by impaired amino acid signaling.
    Guerra ML; Wauson EM; McGlynn K; Cobb MH
    J Biol Chem; 2014 May; 289(20):14370-9. PubMed ID: 24695728
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SPARC promotes insulin secretion through down-regulation of RGS4 protein in pancreatic β cells.
    Hu L; He F; Huang M; Zhao Q; Cheng L; Said N; Zhou Z; Liu F; Dai YS
    Sci Rep; 2020 Oct; 10(1):17581. PubMed ID: 33067534
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular organization of the complex between the muscarinic M3 receptor and the regulator of G protein signaling, Gbeta(5)-RGS7.
    Sandiford SL; Wang Q; Levay K; Buchwald P; Slepak VZ
    Biochemistry; 2010 Jun; 49(24):4998-5006. PubMed ID: 20443543
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Purification and in vitro functional analysis of R7 subfamily RGS proteins in complex with Gbeta5.
    Hooks SB; Harden TK
    Methods Enzymol; 2004; 390():163-77. PubMed ID: 15488177
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulator of G Protein Signaling 7 (RGS7) Can Exist in a Homo-oligomeric Form That Is Regulated by Gαo and R7-binding Protein.
    Tayou J; Wang Q; Jang GF; Pronin AN; Orlandi C; Martemyanov KA; Crabb JW; Slepak VZ
    J Biol Chem; 2016 Apr; 291(17):9133-47. PubMed ID: 26895961
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins.
    Porter MY; Xie K; Pozharski E; Koelle MR; Martemyanov KA
    J Biol Chem; 2010 Dec; 285(52):41100-12. PubMed ID: 20959458
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure, function, and localization of Gβ5-RGS complexes.
    Slepak VZ
    Prog Mol Biol Transl Sci; 2009; 86():157-203. PubMed ID: 20374716
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Association of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons.
    Fajardo-Serrano A; Wydeven N; Young D; Watanabe M; Shigemoto R; Martemyanov KA; Wickman K; Luján R
    Hippocampus; 2013 Dec; 23(12):1231-45. PubMed ID: 23804514
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RGS11 interacts preferentially with R7BP over Galpha(oa)--characterization of Gbeta5-free RGS11.
    Saleem Y; Kim KS
    Biochem Biophys Res Commun; 2009 Aug; 386(1):65-70. PubMed ID: 19497306
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Minireview: Novel aspects of M3 muscarinic receptor signaling in pancreatic β-cells.
    Nakajima K; Jain S; Ruiz de Azua I; McMillin SM; Rossi M; Wess J
    Mol Endocrinol; 2013 Aug; 27(8):1208-16. PubMed ID: 23820900
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Assays of nuclear localization of R7/Gbeta5 complexes.
    Simonds WF; Woodard GE; Zhang JH
    Methods Enzymol; 2004; 390():210-23. PubMed ID: 15488180
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and functional characterization of a novel, arrestin-biased designer G protein-coupled receptor.
    Nakajima K; Wess J
    Mol Pharmacol; 2012 Oct; 82(4):575-82. PubMed ID: 22821234
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RGS6, but not RGS4, is the dominant regulator of G protein signaling (RGS) modulator of the parasympathetic regulation of mouse heart rate.
    Wydeven N; Posokhova E; Xia Z; Martemyanov KA; Wickman K
    J Biol Chem; 2014 Jan; 289(4):2440-9. PubMed ID: 24318880
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.