BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

240 related articles for article (PubMed ID: 28688277)

  • 1. Synthesis, antitumor activity and CDK1 inhibiton of new thiazole nortopsentin analogues.
    Parrino B; Attanzio A; Spanò V; Cascioferro S; Montalbano A; Barraja P; Tesoriere L; Diana P; Cirrincione G; Carbone A
    Eur J Med Chem; 2017 Sep; 138():371-383. PubMed ID: 28688277
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin analogues with antiproliferative activity.
    Parrino B; Carbone A; Di Vita G; Ciancimino C; Attanzio A; Spanò V; Montalbano A; Barraja P; Tesoriere L; Livrea MA; Diana P; Cirrincione G
    Mar Drugs; 2015 Apr; 13(4):1901-24. PubMed ID: 25854642
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs.
    Spanò V; Attanzio A; Cascioferro S; Carbone A; Montalbano A; Barraja P; Tesoriere L; Cirrincione G; Diana P; Parrino B
    Mar Drugs; 2016 Dec; 14(12):. PubMed ID: 27983614
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3,5-bis(3'-indolyl)pyrazoles, analogues of marine alkaloid nortopsentin: synthesis and antitumor properties.
    Diana P; Carbone A; Barraja P; Martorana A; Gia O; DallaVia L; Cirrincione G
    Bioorg Med Chem Lett; 2007 Nov; 17(22):6134-7. PubMed ID: 17911018
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and antiproliferative activity of substituted 3[2-(1H-indol-3-yl)- 1,3-thiazol-4-yl]-1H-pyrrolo[3,2-b]pyridines, marine alkaloid nortopsentin analogues.
    Carbone A; Pennati M; Barraja P; Montalbano A; Parrino B; Spanò V; Lopergolo A; Sbarra S; Doldi V; Zaffaroni N; Cirrincione G; Diana P
    Curr Med Chem; 2014; 21(14):1654-66. PubMed ID: 24180279
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of 4-(2,3-dihydro-1H-benzo[d]pyrrolo[1,2-a]imidazol-7-yl)-N-(5-(piperazin-1-ylmethyl)pyridine-2-yl)pyrimidin-2-amine as a highly potent and selective cyclin-dependent kinases 4 and 6 inhibitors and the discovery of structure-activity relationships.
    Wang Y; Liu WJ; Yin L; Li H; Chen ZH; Zhu DX; Song XQ; Cheng ZZ; Song P; Wang Z; Li ZG
    Bioorg Med Chem Lett; 2018 Mar; 28(5):974-978. PubMed ID: 29429832
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and antiproliferative activity of 2,5-bis(3'-indolyl)pyrroles, analogues of the marine alkaloid nortopsentin.
    Carbone A; Parrino B; Barraja P; Spanò V; Cirrincione G; Diana P; Maier A; Kelter G; Fiebig HH
    Mar Drugs; 2013 Mar; 11(3):643-54. PubMed ID: 23455514
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 1,2,4-Oxadiazole Topsentin Analogs with Antiproliferative Activity against Pancreatic Cancer Cells, Targeting GSK3β Kinase.
    Carbone D; Parrino B; Cascioferro S; Pecoraro C; Giovannetti E; Di Sarno V; Musella S; Auriemma G; Cirrincione G; Diana P
    ChemMedChem; 2021 Feb; 16(3):537-554. PubMed ID: 33141472
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and Cytotoxic Activity of Novel Mono- and Bis-Indole Derivatives: Analogues of Marine Alkaloid Nortopsentin.
    Kamel MM; Abdel-Hameid MK; El-Nassan HB; El-Khouly EA
    Med Chem; 2021; 17(7):779-789. PubMed ID: 32386499
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of selective and potent cyclin-dependent kinase inhibitors.
    N'gompaza-Diarra J; Bettayeb K; Gresh N; Meijer L; Oumata N
    Eur J Med Chem; 2012 Oct; 56():210-6. PubMed ID: 22982525
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and in vitro antiproliferative activity of amido and amino analogues of the marine alkaloid isogranulatimide.
    Lavrard H; Salvetti B; Mathieu V; Rodriguez F; Kiss R; Delfourne E
    ChemMedChem; 2015 Apr; 10(4):607-9. PubMed ID: 25735892
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pim kinase inhibitory and antiproliferative activity of a novel series of meridianin C derivatives.
    More KN; Jang HW; Hong VS; Lee J
    Bioorg Med Chem Lett; 2014 Jun; 24(11):2424-8. PubMed ID: 24775304
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and antiproliferative activity of the ring system [1,2]oxazolo[4,5-g]indole.
    Barraja P; Caracausi L; Diana P; Spanò V; Montalbano A; Carbone A; Parrino B; Cirrincione G
    ChemMedChem; 2012 Nov; 7(11):1901-4. PubMed ID: 22915307
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and evaluation of novel 7-azaindazolyl-indolyl-maleimide derivatives as antitumor agents and protein kinase C inhibitors.
    Ye Q; Cao J; Zhou X; Lv D; He Q; Yang B; Hu Y
    Bioorg Med Chem; 2009 Jul; 17(13):4763-72. PubMed ID: 19447039
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and evaluation of novel 2-(1H-imidazol-2-yl) pyridine Sorafenib derivatives as potential BRAF inhibitors and anti-tumor agents.
    Jiao Y; Xin BT; Zhang Y; Wu J; Lu X; Zheng Y; Tang W; Zhou X
    Eur J Med Chem; 2015 Jan; 90():170-83. PubMed ID: 25461318
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents.
    Abadi AH; Abou-Seri SM; Abdel-Rahman DE; Klein C; Lozach O; Meijer L
    Eur J Med Chem; 2006 Mar; 41(3):296-305. PubMed ID: 16494969
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, in vitro anticancer activity and in silico studies of certain pyrazole-based derivatives as potential inhibitors of cyclin dependent kinases (CDKs).
    Mohammed EZ; Mahmoud WR; George RF; Hassan GS; Omar FA; Georgey HH
    Bioorg Chem; 2021 Nov; 116():105347. PubMed ID: 34555628
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery of pyrrolospirooxindole derivatives as novel cyclin dependent kinase 4 (CDK4) inhibitors by catalyst-free, green approach.
    Kamal A; Mahesh R; Nayak VL; Babu KS; Kumar GB; Shaik AB; Kapure JS; Alarifi A
    Eur J Med Chem; 2016 Jan; 108():476-485. PubMed ID: 26708114
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New imidazo[2,1-b]thiazole derivatives: synthesis, in vitro anticancer evaluation, and in silico studies.
    Park JH; El-Gamal MI; Lee YS; Oh CH
    Eur J Med Chem; 2011 Dec; 46(12):5769-77. PubMed ID: 22033063
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and biological evaluation of N9-cis-cyclobutylpurine derivatives for use as cyclin-dependent kinase (CDK) inhibitors.
    Park SJ; Kim E; Yoo M; Lee JY; Park CH; Hwang JY; Ha JD
    Bioorg Med Chem Lett; 2017 Sep; 27(18):4399-4404. PubMed ID: 28827110
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.