BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 28689991)

  • 1. Ubiquitin phosphorylated at Ser57 hyper-activates parkin.
    George S; Wang SM; Bi Y; Treidlinger M; Barber KR; Shaw GS; O'Donoghue P
    Biochim Biophys Acta Gen Subj; 2017 Nov; 1861(11 Pt B):3038-3046. PubMed ID: 28689991
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy.
    Ordureau A; Heo JM; Duda DM; Paulo JA; Olszewski JL; Yanishevski D; Rinehart J; Schulman BA; Harper JW
    Proc Natl Acad Sci U S A; 2015 May; 112(21):6637-42. PubMed ID: 25969509
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Generation of phospho-ubiquitin variants by orthogonal translation reveals codon skipping.
    George S; Aguirre JD; Spratt DE; Bi Y; Jeffery M; Shaw GS; O'Donoghue P
    FEBS Lett; 2016 May; 590(10):1530-42. PubMed ID: 27096575
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation.
    Kazlauskaite A; Martínez-Torres RJ; Wilkie S; Kumar A; Peltier J; Gonzalez A; Johnson C; Zhang J; Hope AG; Peggie M; Trost M; van Aalten DM; Alessi DR; Prescott AR; Knebel A; Walden H; Muqit MM
    EMBO Rep; 2015 Aug; 16(8):939-54. PubMed ID: 26116755
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications.
    Durcan TM; Fon EA
    Genes Dev; 2015 May; 29(10):989-99. PubMed ID: 25995186
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Ubl/ubiquitin switch in the activation of Parkin.
    Sauvé V; Lilov A; Seirafi M; Vranas M; Rasool S; Kozlov G; Sprules T; Wang J; Trempe JF; Gehring K
    EMBO J; 2015 Oct; 34(20):2492-505. PubMed ID: 26254305
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinct phosphorylation signals drive acceptor versus free ubiquitin chain targeting by parkin.
    Dunkerley KM; Rintala-Dempsey AC; Salzano G; Tadayon R; Hadi D; Barber KR; Walden H; Shaw GS
    Biochem J; 2022 Mar; 479(6):751-766. PubMed ID: 35262643
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.
    Kazlauskaite A; Kondapalli C; Gourlay R; Campbell DG; Ritorto MS; Hofmann K; Alessi DR; Knebel A; Trost M; Muqit MM
    Biochem J; 2014 May; 460(1):127-39. PubMed ID: 24660806
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin.
    Caulfield TR; Fiesel FC; Moussaud-Lamodière EL; Dourado DF; Flores SC; Springer W
    PLoS Comput Biol; 2014 Nov; 10(11):e1003935. PubMed ID: 25375667
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation.
    Tang MY; Vranas M; Krahn AI; Pundlik S; Trempe JF; Fon EA
    Nat Commun; 2017 Mar; 8():14697. PubMed ID: 28276439
    [TBL] [Abstract][Full Text] [Related]  

  • 11. (Patho-)physiological relevance of PINK1-dependent ubiquitin phosphorylation.
    Fiesel FC; Ando M; Hudec R; Hill AR; Castanedes-Casey M; Caulfield TR; Moussaud-Lamodière EL; Stankowski JN; Bauer PO; Lorenzo-Betancor O; Ferrer I; Arbelo JM; Siuda J; Chen L; Dawson VL; Dawson TM; Wszolek ZK; Ross OA; Dickson DW; Springer W
    EMBO Rep; 2015 Sep; 16(9):1114-30. PubMed ID: 26162776
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Monitoring PARKIN RBR Ubiquitin Ligase Activation States with UbFluor.
    Foote PK; Statsyuk AV
    Curr Protoc Chem Biol; 2018 Sep; 10(3):e45. PubMed ID: 30063295
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Impact of different ionization states of phosphorylated Serine-65 on ubiquitin structure and interactions.
    Kazansky Y; Lai MY; Singh RK; Fushman D
    Sci Rep; 2018 Feb; 8(1):2651. PubMed ID: 29422536
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of the E3 ubiquitin ligase Parkin.
    Caulfield TR; Fiesel FC; Springer W
    Biochem Soc Trans; 2015 Apr; 43(2):269-74. PubMed ID: 25849928
    [TBL] [Abstract][Full Text] [Related]  

  • 15. UbMES and UbFluor: Novel probes for ring-between-ring (RBR) E3 ubiquitin ligase PARKIN.
    Park S; Foote PK; Krist DT; Rice SE; Statsyuk AV
    J Biol Chem; 2017 Oct; 292(40):16539-16553. PubMed ID: 28710279
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease.
    Shiba-Fukushima K; Ishikawa KI; Inoshita T; Izawa N; Takanashi M; Sato S; Onodera O; Akamatsu W; Okano H; Imai Y; Hattori N
    Hum Mol Genet; 2017 Aug; 26(16):3172-3185. PubMed ID: 28541509
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.
    Wauer T; Swatek KN; Wagstaff JL; Gladkova C; Pruneda JN; Michel MA; Gersch M; Johnson CM; Freund SM; Komander D
    EMBO J; 2015 Feb; 34(3):307-25. PubMed ID: 25527291
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expanding the ubiquitin code through post-translational modification.
    Herhaus L; Dikic I
    EMBO Rep; 2015 Sep; 16(9):1071-83. PubMed ID: 26268526
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural insights into Parkin substrate lysine targeting from minimal Miro substrates.
    Klosowiak JL; Park S; Smith KP; French ME; Focia PJ; Freymann DM; Rice SE
    Sci Rep; 2016 Sep; 6():33019. PubMed ID: 27605430
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective localization of Mfn2 near PINK1 enables its preferential ubiquitination by Parkin on mitochondria.
    Vranas M; Lu Y; Rasool S; Croteau N; Krett JD; Sauvé V; Gehring K; Fon EA; Durcan TM; Trempe JF
    Open Biol; 2022 Jan; 12(1):210255. PubMed ID: 35042405
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.