BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 28692044)

  • 1. Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells.
    Trinidad AG; Whalley N; Rowlinson R; Delpuech O; Dudley P; Rooney C; Critchlow SE
    Oncogene; 2017 Nov; 36(44):6164-6176. PubMed ID: 28692044
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Targeting metabolic reprogramming in KRAS-driven cancers.
    Kawada K; Toda K; Sakai Y
    Int J Clin Oncol; 2017 Aug; 22(4):651-659. PubMed ID: 28647837
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SLC25A22 Promotes Proliferation and Survival of Colorectal Cancer Cells With KRAS Mutations and Xenograft Tumor Progression in Mice via Intracellular Synthesis of Aspartate.
    Wong CC; Qian Y; Li X; Xu J; Kang W; Tong JH; To KF; Jin Y; Li W; Chen H; Go MY; Wu JL; Cheng KW; Ng SS; Sung JJ; Cai Z; Yu J
    Gastroenterology; 2016 Nov; 151(5):945-960.e6. PubMed ID: 27451147
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Survivin knockdown induces senescence in TTF‑1-expressing, KRAS-mutant lung adenocarcinomas.
    Sumi T; Hirai S; Yamaguchi M; Tanaka Y; Tada M; Yamada G; Hasegawa T; Miyagi Y; Niki T; Watanabe A; Takahashi H; Sakuma Y
    Int J Oncol; 2018 Jul; 53(1):33-46. PubMed ID: 29658609
    [TBL] [Abstract][Full Text] [Related]  

  • 5. FOSL1 Promotes Kras-induced Lung Cancer through Amphiregulin and Cell Survival Gene Regulation.
    Elangovan IM; Vaz M; Tamatam CR; Potteti HR; Reddy NM; Reddy SP
    Am J Respir Cell Mol Biol; 2018 May; 58(5):625-635. PubMed ID: 29112457
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Baseline MAPK signaling activity confers intrinsic radioresistance to KRAS-mutant colorectal carcinoma cells by rapid upregulation of heterogeneous nuclear ribonucleoprotein K (hnRNP K).
    Eder S; Arndt A; Lamkowski A; Daskalaki W; Rump A; Priller M; Genze F; Wardelmann E; Port M; Steinestel K
    Cancer Lett; 2017 Jan; 385():160-167. PubMed ID: 27793696
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Co-dependency of PKCδ and K-Ras: inverse association with cytotoxic drug sensitivity in KRAS mutant lung cancer.
    Ohm AM; Tan AC; Heasley LE; Reyland ME
    Oncogene; 2017 Jul; 36(30):4370-4378. PubMed ID: 28368426
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Clinical Role of ASCT2 (SLC1A5) in KRAS-Mutated Colorectal Cancer.
    Toda K; Nishikawa G; Iwamoto M; Itatani Y; Takahashi R; Sakai Y; Kawada K
    Int J Mol Sci; 2017 Jul; 18(8):. PubMed ID: 28749408
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Specific inhibition of p110α subunit of PI3K: putative therapeutic strategy for KRAS mutant colorectal cancers.
    Fernandes MS; Melo S; Velho S; Carneiro P; Carneiro F; Seruca R
    Oncotarget; 2016 Oct; 7(42):68546-68558. PubMed ID: 27602501
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Genome-Wide CRISPR Screen for Essential Cell Growth Mediators in Mutant KRAS Colorectal Cancers.
    Yau EH; Kummetha IR; Lichinchi G; Tang R; Zhang Y; Rana TM
    Cancer Res; 2017 Nov; 77(22):6330-6339. PubMed ID: 28954733
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kras mutations increase telomerase activity and targeting telomerase is a promising therapeutic strategy for Kras-mutant NSCLC.
    Liu W; Yin Y; Wang J; Shi B; Zhang L; Qian D; Li C; Zhang H; Wang S; Zhu J; Gao L; Zhang Q; Jia B; Hao L; Wang C; Zhang B
    Oncotarget; 2017 Jan; 8(1):179-190. PubMed ID: 27329725
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dual blockade of macropinocytosis and asparagine bioavailability shows synergistic anti-tumor effects on KRAS-mutant colorectal cancer.
    Hanada K; Kawada K; Nishikawa G; Toda K; Maekawa H; Nishikawa Y; Masui H; Hirata W; Okamoto M; Kiyasu Y; Honma S; Ogawa R; Mizuno R; Itatani Y; Miyoshi H; Sasazuki T; Shirasawa S; Taketo MM; Obama K; Sakai Y
    Cancer Lett; 2021 Dec; 522():129-141. PubMed ID: 34543685
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Downregulation of miR‑143 modulates KRAS expression in colorectal carcinoma cells.
    Liu H; Liu J; Huo J; Li K; Li K; Guo H; Yang Y
    Oncol Rep; 2019 Dec; 42(6):2759-2767. PubMed ID: 31638218
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
    Najumudeen AK; Ceteci F; Fey SK; Hamm G; Steven RT; Hall H; Nikula CJ; Dexter A; Murta T; Race AM; Sumpton D; Vlahov N; Gay DM; Knight JRP; Jackstadt R; Leach JDG; Ridgway RA; Johnson ER; Nixon C; Hedley A; Gilroy K; Clark W; Malla SB; Dunne PD; Rodriguez-Blanco G; Critchlow SE; Mrowinska A; Malviya G; Solovyev D; Brown G; Lewis DY; Mackay GM; Strathdee D; Tardito S; Gottlieb E; ; Takats Z; Barry ST; Goodwin RJA; Bunch J; Bushell M; Campbell AD; Sansom OJ
    Nat Genet; 2021 Jan; 53(1):16-26. PubMed ID: 33414552
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bilateral blockade of MEK- and PI3K-mediated pathways downstream of mutant KRAS as a treatment approach for peritoneal mucinous malignancies.
    Kuracha MR; Thomas P; Loggie BW; Govindarajan V
    PLoS One; 2017; 12(6):e0179510. PubMed ID: 28640835
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enhanced dependency of KRAS-mutant colorectal cancer cells on RAD51-dependent homologous recombination repair identified from genetic interactions in Saccharomyces cerevisiae.
    Kalimutho M; Bain AL; Mukherjee B; Nag P; Nanayakkara DM; Harten SK; Harris JL; Subramanian GN; Sinha D; Shirasawa S; Srihari S; Burma S; Khanna KK
    Mol Oncol; 2017 May; 11(5):470-490. PubMed ID: 28173629
    [TBL] [Abstract][Full Text] [Related]  

  • 17. KRAS-mutation status dependent effect of zoledronic acid in human non-small cell cancer preclinical models.
    Kenessey I; Kói K; Horváth O; Cserepes M; Molnár D; Izsák V; Dobos J; Hegedűs B; Tóvári J; Tímár J
    Oncotarget; 2016 Nov; 7(48):79503-79514. PubMed ID: 27780929
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Oncogenic KRAS creates an aspartate metabolism signature in colorectal cancer cells.
    Doubleday PF; Fornelli L; Ntai I; Kelleher NL
    FEBS J; 2021 Dec; 288(23):6683-6699. PubMed ID: 34227245
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.
    Toda K; Kawada K; Iwamoto M; Inamoto S; Sasazuki T; Shirasawa S; Hasegawa S; Sakai Y
    Neoplasia; 2016 Nov; 18(11):654-665. PubMed ID: 27764698
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Concomitant mutations and splice variants in KRAS and BRAF demonstrate complex perturbation of the Ras/Raf signalling pathway in advanced colorectal cancer.
    Seth R; Crook S; Ibrahem S; Fadhil W; Jackson D; Ilyas M
    Gut; 2009 Sep; 58(9):1234-41. PubMed ID: 19474002
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.