365 related articles for article (PubMed ID: 28694431)
1. Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes.
Wu W; Bush KT; Nigam SK
Sci Rep; 2017 Jul; 7(1):4939. PubMed ID: 28694431
[TBL] [Abstract][Full Text] [Related]
2. Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease.
Bush KT; Singh P; Nigam SK
JCI Insight; 2020 Apr; 5(7):. PubMed ID: 32271169
[TBL] [Abstract][Full Text] [Related]
3. Unique metabolite preferences of the drug transporters OAT1 and OAT3 analyzed by machine learning.
Nigam AK; Li JG; Lall K; Shi D; Bush KT; Bhatnagar V; Abagyan R; Nigam SK
J Biol Chem; 2020 Feb; 295(7):1829-1842. PubMed ID: 31896576
[TBL] [Abstract][Full Text] [Related]
4. The drug transporter OAT3 (SLC22A8) and endogenous metabolite communication via the gut-liver-kidney axis.
Bush KT; Wu W; Lun C; Nigam SK
J Biol Chem; 2017 Sep; 292(38):15789-15803. PubMed ID: 28765282
[TBL] [Abstract][Full Text] [Related]
5. Coordinate regulation of systemic and kidney tryptophan metabolism by the drug transporters OAT1 and OAT3.
Granados JC; Richelle A; Gutierrez JM; Zhang P; Zhang X; Bhatnagar V; Lewis NE; Nigam SK
J Biol Chem; 2021; 296():100575. PubMed ID: 33757768
[TBL] [Abstract][Full Text] [Related]
6. Characterization of uremic toxin transport by organic anion transporters in the kidney.
Deguchi T; Kusuhara H; Takadate A; Endou H; Otagiri M; Sugiyama Y
Kidney Int; 2004 Jan; 65(1):162-74. PubMed ID: 14675047
[TBL] [Abstract][Full Text] [Related]
7. Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters.
Nigam SK; Wu W; Bush KT; Hoenig MP; Blantz RC; Bhatnagar V
Clin J Am Soc Nephrol; 2015 Nov; 10(11):2039-49. PubMed ID: 26490509
[TBL] [Abstract][Full Text] [Related]
8. Identification and Quantitative Assessment of Uremic Solutes as Inhibitors of Renal Organic Anion Transporters, OAT1 and OAT3.
Hsueh CH; Yoshida K; Zhao P; Meyer TW; Zhang L; Huang SM; Giacomini KM
Mol Pharm; 2016 Sep; 13(9):3130-40. PubMed ID: 27467266
[TBL] [Abstract][Full Text] [Related]
9. Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue.
Nagle MA; Wu W; Eraly SA; Nigam SK
Neurosci Lett; 2013 Feb; 534():133-8. PubMed ID: 23196129
[TBL] [Abstract][Full Text] [Related]
10. Untargeted metabolomics identifies enterobiome metabolites and putative uremic toxins as substrates of organic anion transporter 1 (Oat1).
Wikoff WR; Nagle MA; Kouznetsova VL; Tsigelny IF; Nigam SK
J Proteome Res; 2011 Jun; 10(6):2842-51. PubMed ID: 21476605
[TBL] [Abstract][Full Text] [Related]
11. Blockade of Organic Anion Transport in Humans After Treatment With the Drug Probenecid Leads to Major Metabolic Alterations in Plasma and Urine.
Granados JC; Bhatnagar V; Nigam SK
Clin Pharmacol Ther; 2022 Sep; 112(3):653-664. PubMed ID: 35490380
[TBL] [Abstract][Full Text] [Related]
12. Uremic Toxins in Organ Crosstalk.
Lowenstein J; Nigam SK
Front Med (Lausanne); 2021; 8():592602. PubMed ID: 33937275
[TBL] [Abstract][Full Text] [Related]
13. The kidney and uremic toxin removal: glomerulus or tubule?
Masereeuw R; Mutsaers HA; Toyohara T; Abe T; Jhawar S; Sweet DH; Lowenstein J
Semin Nephrol; 2014 Mar; 34(2):191-208. PubMed ID: 24780473
[TBL] [Abstract][Full Text] [Related]
14. Evaluation of the impact of gut microbiota on uremic solute accumulation by a CE-TOFMS-based metabolomics approach.
Mishima E; Fukuda S; Mukawa C; Yuri A; Kanemitsu Y; Matsumoto Y; Akiyama Y; Fukuda NN; Tsukamoto H; Asaji K; Shima H; Kikuchi K; Suzuki C; Suzuki T; Tomioka Y; Soga T; Ito S; Abe T
Kidney Int; 2017 Sep; 92(3):634-645. PubMed ID: 28396122
[TBL] [Abstract][Full Text] [Related]
15. The SLC22 Transporter Family: A Paradigm for the Impact of Drug Transporters on Metabolic Pathways, Signaling, and Disease.
Nigam SK
Annu Rev Pharmacol Toxicol; 2018 Jan; 58():663-687. PubMed ID: 29309257
[TBL] [Abstract][Full Text] [Related]
16. Remote effects of kidney drug transporter OAT1 on gut microbiome composition and urate homeostasis.
Ermakov VS; Granados JC; Nigam SK
JCI Insight; 2023 Nov; 8(21):. PubMed ID: 37937647
[TBL] [Abstract][Full Text] [Related]
17. Drug transporters OAT1 and OAT3 have specific effects on multiple organs and gut microbiome as revealed by contextualized metabolic network reconstructions.
Jamshidi N; Nigam SK
Sci Rep; 2022 Oct; 12(1):18308. PubMed ID: 36316339
[TBL] [Abstract][Full Text] [Related]
18. The kidney drug transporter OAT1 regulates gut microbiome-dependent host metabolism.
Granados JC; Ermakov V; Maity K; Vera DR; Chang G; Nigam SK
JCI Insight; 2023 Jan; 8(2):. PubMed ID: 36692015
[TBL] [Abstract][Full Text] [Related]
19. Altered Renal Expression of Relevant Clinical Drug Transporters in Different Models of Acute Uremia in Rats. Role of Urea Levels.
Brandoni A; Torres AM
Cell Physiol Biochem; 2015; 36(3):907-16. PubMed ID: 26065488
[TBL] [Abstract][Full Text] [Related]
20. Tenofovir alafenamide is not a substrate for renal organic anion transporters (OATs) and does not exhibit OAT-dependent cytotoxicity.
Bam RA; Yant SR; Cihlar T
Antivir Ther; 2014; 19(7):687-92. PubMed ID: 24699134
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
