BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

387 related articles for article (PubMed ID: 28698210)

  • 1. APOBEC3A and APOBEC3B Activities Render Cancer Cells Susceptible to ATR Inhibition.
    Buisson R; Lawrence MS; Benes CH; Zou L
    Cancer Res; 2017 Sep; 77(17):4567-4578. PubMed ID: 28698210
    [TBL] [Abstract][Full Text] [Related]  

  • 2. APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication.
    Hoopes JI; Cortez LM; Mertz TM; Malc EP; Mieczkowski PA; Roberts SA
    Cell Rep; 2016 Feb; 14(6):1273-1282. PubMed ID: 26832400
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression.
    Warren CJ; Westrich JA; Doorslaer KV; Pyeon D
    Viruses; 2017 Aug; 9(8):. PubMed ID: 28825669
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment.
    Vural S; Simon R; Krushkal J
    Hum Genomics; 2018 Apr; 12(1):20. PubMed ID: 29642934
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mesoscale DNA features impact APOBEC3A and APOBEC3B deaminase activity and shape tumor mutational landscapes.
    Sanchez A; Ortega P; Sakhtemani R; Manjunath L; Oh S; Bournique E; Becker A; Kim K; Durfee C; Temiz NA; Chen XS; Harris RS; Lawrence MS; Buisson R
    Nat Commun; 2024 Mar; 15(1):2370. PubMed ID: 38499542
    [TBL] [Abstract][Full Text] [Related]  

  • 6. APOBEC3B coordinates R-loop to promote replication stress and sensitize cancer cells to ATR/Chk1 inhibitors.
    Zong C; Zhang Z; Gao L; He J; Wang Y; Li Q; Liu X; Yang J; Chen D; Huang R; Zheng G; Jin X; Wei W; Jia R; Shen J
    Cell Death Dis; 2023 Jun; 14(6):348. PubMed ID: 37270643
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytosine Deaminase APOBEC3A Sensitizes Leukemia Cells to Inhibition of the DNA Replication Checkpoint.
    Green AM; Budagyan K; Hayer KE; Reed MA; Savani MR; Wertheim GB; Weitzman MD
    Cancer Res; 2017 Sep; 77(17):4579-4588. PubMed ID: 28655787
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA replication stress: a source of APOBEC3B expression in breast cancer.
    Cescon DW; Haibe-Kains B
    Genome Biol; 2016 Sep; 17(1):202. PubMed ID: 27716362
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells.
    Nikkilä J; Kumar R; Campbell J; Brandsma I; Pemberton HN; Wallberg F; Nagy K; Scheer I; Vertessy BG; Serebrenik AA; Monni V; Harris RS; Pettitt SJ; Ashworth A; Lord CJ
    Br J Cancer; 2017 Jun; 117(1):113-123. PubMed ID: 28535155
    [TBL] [Abstract][Full Text] [Related]  

  • 10. APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability.
    Kawale AS; Ran X; Patel PS; Saxena S; Lawrence MS; Zou L
    Sci Adv; 2024 Jan; 10(3):eadk2771. PubMed ID: 38241374
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers.
    Chan K; Roberts SA; Klimczak LJ; Sterling JF; Saini N; Malc EP; Kim J; Kwiatkowski DJ; Fargo DC; Mieczkowski PA; Getz G; Gordenin DA
    Nat Genet; 2015 Sep; 47(9):1067-72. PubMed ID: 26258849
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enzyme cycling contributes to efficient induction of genome mutagenesis by the cytidine deaminase APOBEC3B.
    Adolph MB; Love RP; Feng Y; Chelico L
    Nucleic Acids Res; 2017 Nov; 45(20):11925-11940. PubMed ID: 28981865
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Tumor-Promoting Phorbol Ester Causes a Large Increase in APOBEC3A Expression and a Moderate Increase in APOBEC3B Expression in a Normal Human Keratinocyte Cell Line without Increasing Genomic Uracils.
    Siriwardena SU; Perera MLW; Senevirathne V; Stewart J; Bhagwat AS
    Mol Cell Biol; 2019 Jan; 39(1):. PubMed ID: 30348839
    [TBL] [Abstract][Full Text] [Related]  

  • 14. APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells.
    Bogerd HP; Wiegand HL; Doehle BP; Lueders KK; Cullen BR
    Nucleic Acids Res; 2006; 34(1):89-95. PubMed ID: 16407327
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-Dependent Manner.
    Zhao K; Zhang Q; Flanagan SA; Lang X; Jiang L; Parsels LA; Parsels JD; Zou W; Lawrence TS; Buisson R; Green MD; Morgan MA
    Mol Cancer Res; 2021 Sep; 19(9):1571-1582. PubMed ID: 34045311
    [TBL] [Abstract][Full Text] [Related]  

  • 16. APOBEC3A is a prominent cytidine deaminase in breast cancer.
    Cortez LM; Brown AL; Dennis MA; Collins CD; Brown AJ; Mitchell D; Mertz TM; Roberts SA
    PLoS Genet; 2019 Dec; 15(12):e1008545. PubMed ID: 31841499
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ancestral APOBEC3B Nuclear Localization Is Maintained in Humans and Apes and Altered in Most Other Old World Primate Species.
    Auerbach AA; Becker JT; Moraes SN; Moghadasi SA; Duda JM; Salamango DJ; Harris RS
    mSphere; 2022 Dec; 7(6):e0045122. PubMed ID: 36374108
    [TBL] [Abstract][Full Text] [Related]  

  • 18. APOBEC3B edits HBV DNA and inhibits HBV replication during reverse transcription.
    Chen Y; Hu J; Cai X; Huang Y; Zhou X; Tu Z; Hu J; Tavis JE; Tang N; Huang A; Hu Y
    Antiviral Res; 2018 Jan; 149():16-25. PubMed ID: 29129707
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer.
    Carpenter MA; Temiz NA; Ibrahim MA; Jarvis MC; Brown MR; Argyris PP; Brown WL; Starrett GJ; Yee D; Harris RS
    PLoS Genet; 2023 Nov; 19(11):e1011043. PubMed ID: 38033156
    [TBL] [Abstract][Full Text] [Related]  

  • 20. HMCES Maintains Replication Fork Progression and Prevents Double-Strand Breaks in Response to APOBEC Deamination and Abasic Site Formation.
    Mehta KPM; Lovejoy CA; Zhao R; Heintzman DR; Cortez D
    Cell Rep; 2020 Jun; 31(9):107705. PubMed ID: 32492421
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.