BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

394 related articles for article (PubMed ID: 28707655)

  • 1. [The FUS protein: Physiological functions and a role in amyotrophic lateral sclerosis].
    Efimova AD; Ovchinnikov RK; Roman AY; Maltsev AV; Grigoriev VV; Kovrazhkina EA; Skvortsova VI
    Mol Biol (Mosk); 2017; 51(3):387-399. PubMed ID: 28707655
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.
    Naumann M; Pal A; Goswami A; Lojewski X; Japtok J; Vehlow A; Naujock M; Günther R; Jin M; Stanslowsky N; Reinhardt P; Sterneckert J; Frickenhaus M; Pan-Montojo F; Storkebaum E; Poser I; Freischmidt A; Weishaupt JH; Holzmann K; Troost D; Ludolph AC; Boeckers TM; Liebau S; Petri S; Cordes N; Hyman AA; Wegner F; Grill SW; Weis J; Storch A; Hermann A
    Nat Commun; 2018 Jan; 9(1):335. PubMed ID: 29362359
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aggregation of FET Proteins as a Pathological Change in Amyotrophic Lateral Sclerosis.
    Furukawa Y; Tokuda E
    Adv Exp Med Biol; 2017; 925():1-12. PubMed ID: 27311318
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human TDP-43 and FUS selectively affect motor neuron maturation and survival in a murine cell model of ALS by non-cell-autonomous mechanisms.
    Wächter N; Storch A; Hermann A
    Amyotroph Lateral Scler Frontotemporal Degener; 2015; 16(7-8):431-41. PubMed ID: 26174443
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in 'FUSDelta14' knockin mice.
    Devoy A; Kalmar B; Stewart M; Park H; Burke B; Noy SJ; Redhead Y; Humphrey J; Lo K; Jaeger J; Mejia Maza A; Sivakumar P; Bertolin C; Soraru G; Plagnol V; Greensmith L; Acevedo Arozena A; Isaacs AM; Davies B; Fratta P; Fisher EMC
    Brain; 2017 Nov; 140(11):2797-2805. PubMed ID: 29053787
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanisms of FUS mutations in familial amyotrophic lateral sclerosis.
    Shang Y; Huang EJ
    Brain Res; 2016 Sep; 1647():65-78. PubMed ID: 27033831
    [TBL] [Abstract][Full Text] [Related]  

  • 7. TDP-43 and FUS/TLS: sending a complex message about messenger RNA in amyotrophic lateral sclerosis?
    Strong MJ; Volkening K
    FEBS J; 2011 Oct; 278(19):3569-77. PubMed ID: 21810174
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis.
    Kwiatkowski TJ; Bosco DA; Leclerc AL; Tamrazian E; Vanderburg CR; Russ C; Davis A; Gilchrist J; Kasarskis EJ; Munsat T; Valdmanis P; Rouleau GA; Hosler BA; Cortelli P; de Jong PJ; Yoshinaga Y; Haines JL; Pericak-Vance MA; Yan J; Ticozzi N; Siddique T; McKenna-Yasek D; Sapp PC; Horvitz HR; Landers JE; Brown RH
    Science; 2009 Feb; 323(5918):1205-8. PubMed ID: 19251627
    [TBL] [Abstract][Full Text] [Related]  

  • 9. U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish.
    Yu Y; Chi B; Xia W; Gangopadhyay J; Yamazaki T; Winkelbauer-Hurt ME; Yin S; Eliasse Y; Adams E; Shaw CE; Reed R
    Nucleic Acids Res; 2015 Mar; 43(6):3208-18. PubMed ID: 25735748
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amyotrophic Lateral Sclerosis, FUS and Protein Synthesis Defects.
    Assoni AF; Foijer F; Zatz M
    Stem Cell Rev Rep; 2023 Apr; 19(3):625-638. PubMed ID: 36515764
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription.
    Yamaguchi A; Takanashi K
    Sci Rep; 2016 Oct; 6():35195. PubMed ID: 27731383
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways.
    Blokhuis AM; Koppers M; Groen EJN; van den Heuvel DMA; Dini Modigliani S; Anink JJ; Fumoto K; van Diggelen F; Snelting A; Sodaar P; Verheijen BM; Demmers JAA; Veldink JH; Aronica E; Bozzoni I; den Hertog J; van den Berg LH; Pasterkamp RJ
    Acta Neuropathol; 2016 Aug; 132(2):175-196. PubMed ID: 27164932
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.
    Daigle JG; Krishnamurthy K; Ramesh N; Casci I; Monaghan J; McAvoy K; Godfrey EW; Daniel DC; Johnson EM; Monahan Z; Shewmaker F; Pasinelli P; Pandey UB
    Acta Neuropathol; 2016 Apr; 131(4):605-20. PubMed ID: 26728149
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Altered mRNP granule dynamics in FTLD pathogenesis.
    Bowden HA; Dormann D
    J Neurochem; 2016 Aug; 138 Suppl 1():112-33. PubMed ID: 26938019
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis.
    Scekic-Zahirovic J; Oussini HE; Mersmann S; Drenner K; Wagner M; Sun Y; Allmeroth K; Dieterlé S; Sinniger J; Dirrig-Grosch S; René F; Dormann D; Haass C; Ludolph AC; Lagier-Tourenne C; Storkebaum E; Dupuis L
    Acta Neuropathol; 2017 Jun; 133(6):887-906. PubMed ID: 28243725
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6.
    Vance C; Rogelj B; Hortobágyi T; De Vos KJ; Nishimura AL; Sreedharan J; Hu X; Smith B; Ruddy D; Wright P; Ganesalingam J; Williams KL; Tripathi V; Al-Saraj S; Al-Chalabi A; Leigh PN; Blair IP; Nicholson G; de Belleroche J; Gallo JM; Miller CC; Shaw CE
    Science; 2009 Feb; 323(5918):1208-1211. PubMed ID: 19251628
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fused in sarcoma (FUS) protein lacking nuclear localization signal (NLS) and major RNA binding motifs triggers proteinopathy and severe motor phenotype in transgenic mice.
    Shelkovnikova TA; Peters OM; Deykin AV; Connor-Robson N; Robinson H; Ustyugov AA; Bachurin SO; Ermolkevich TG; Goldman IL; Sadchikova ER; Kovrazhkina EA; Skvortsova VI; Ling SC; Da Cruz S; Parone PA; Buchman VL; Ninkina NN
    J Biol Chem; 2013 Aug; 288(35):25266-25274. PubMed ID: 23867462
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pur-alpha functionally interacts with FUS carrying ALS-associated mutations.
    Di Salvio M; Piccinni V; Gerbino V; Mantoni F; Camerini S; Lenzi J; Rosa A; Chellini L; Loreni F; Carrì MT; Bozzoni I; Cozzolino M; Cestra G
    Cell Death Dis; 2015 Oct; 6(10):e1943. PubMed ID: 26492376
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
    Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
    Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.
    Japtok J; Lojewski X; Naumann M; Klingenstein M; Reinhardt P; Sterneckert J; Putz S; Demestre M; Boeckers TM; Ludolph AC; Liebau S; Storch A; Hermann A
    Neurobiol Dis; 2015 Oct; 82():420-429. PubMed ID: 26253605
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.